SOX9 Monoclonal Antibody (GMPR9), eBioscience™ | Invitrogen 14-9765-95 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SOX9 Monoclonal Antibody (GMPR9), eBioscience™

catalog :

14-9765-95

quantity :

10 mg

price :

US 3000.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

GMPR9

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

SOX9 Monoclonal Antibody (GMPR9), eBioscience™

Catalog # :

14-9765-95

Quantity :

10 mg

Price :

US 3000.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

ChIP assay: 2.5 µg/10^6 cells, Immunocytochemistry: 1 µg/mL, Immunofluorescence: 1 µg/mL, Immunohistochemistry (Paraffin): 1 µg/mL, Western Blot: 0.5 µg/mL

Species :

Human, Mouse, Rat

Clone :

GMPR9

Isotype :

IgG1, kappa

Storage :

4° C

Description :

SOX9 has a role in sex determination and differentiation of Sertoli cells. It is involved in chondrogenesis and regulates the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes. Translocation of this gene can cause campomelic dysplasia. SOX9 is involved in the formation of testes from the indifferent fetal gonads. It is a major molecular component of the neuron-glia switch in developing spinal cord. During normal development, SOX9 allows the prostate epithelium to outgrow into the mesenchyme and then provides basal cell support for development and maintenance of the luminal epithelium. These functions of SOX9 are subverted in prostate cancer to support tumor growth and invasion. SOX9 may direct the formation of neural crest precursors and the development of a range of neural crest derivative. It has a transcriptional regulation in melanin production in cells. Northern blot analysis shows its expression on adult testis, adult heart, and fetal brain.

Format :

Liquid

Applications w/Dilutions :

ChIP assay: 2.5 µg/10^6 cells, Immunocytochemistry: 1 µg/mL, Immunofluorescence: 1 µg/mL, Immunohistochemistry (Paraffin): 1 µg/mL, Western Blot: 0.5 µg/mL

Aliases :

2010306G03Rik; AV220920; CMD1; CMPD1; mKIAA4243; SOX 9; Sox9; SOX-9; SRA1; SRXX2; SRXY10; SRY (sex determining region Y)-box 9; SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal); SRY (sex determining region Y)-box9; SRY (sex-determining region Y)-box 9 protein; SRY box 9; SRY-box 9; SRY-Box 9 ; SRY-box containing 9; SRY-box containing gene 9; SRY-box containing protein 9; SRY-related HMG-box, gene 9; Transcription factor SOX-9