This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Angiogenin Monoclonal Antibody (26-2F), eBioscience
catalog :
14-9762-82
quantity :
100 ug
price :
US 399.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
26-2F
reactivity :
human
application :
immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 4
Reference
Liu X, Chai Y, Liu G, Su W, Guo Q, Lv X, et al. Osteoclasts protect bone blood vessels against senescence through the angiogenin/plexin-B2 axis. Nat Commun. 2021;12:1832 pubmed publisher
Wei S, Gao X, Du J, Su J, Xu Z. Angiogenin enhances cell migration by regulating stress fiber assembly and focal adhesion dynamics. PLoS ONE. 2011;6:e28797 pubmed publisher
Li S, Hu G. Emerging role of angiogenin in stress response and cell survival under adverse conditions. J Cell Physiol. 2012;227:2822-6 pubmed publisher
Olson K, French T, Vallee B, Fett J. A monoclonal antibody to human angiogenin suppresses tumor growth in athymic mice. Cancer Res. 1994;54:4576-9 pubmed
product information
Product Type :
Antibody
Product Name :
Angiogenin Monoclonal Antibody (26-2F), eBioscience
Catalog # :
14-9762-82
Quantity :
100 ug
Price :
US 399.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
ELISA: Assay-Dependent, Functional Assay: Assay-Dependent, Immunocytochemistry: Assay-Dependent, Immunohistochemistry (Frozen): 20 ug/mL, Immunohistochemistry (Paraffin): 20 ug/mL, Immunoprecipitation: Assay-Dependent, Neutralization: Assay-Dependent
Species :
Human
Clone :
26-2F
Isotype :
IgG1, kappa
Storage :
4 C
Description :
Angiogenin (ANG or ANG I) is important for the process of neovascularization and formation of new blood vessels. ANG is similar to pancreatic ribonuclease A and functions as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. It interacts with endothelial cell-surface actin and may cause changes in the cell cytoskeleton. ANG is thought to be involved in the development of solid tumors and its antagonists are capable of inhibiting tumor growth. Defects in ANG are the cause of susceptibility to amyotrophic lateral sclerosis type 9 (ALS9). Angiogenin is a genetic link between ALS and PD.
Format :
Liquid
Applications w/Dilutions :
ELISA: Assay-Dependent, Functional Assay: Assay-Dependent, Immunocytochemistry: Assay-Dependent, Immunohistochemistry (Frozen): 20 ug/mL, Immunohistochemistry (Paraffin): 20 ug/mL, Immunoprecipitation: Assay-Dependent, Neutralization: Assay-Dependent
Aliases :
AI385586; ALS9; ANG; Ang1; Angiogenin; angiogenin ribonuclease 1; angiogenin, ribonuclease A family, member 1; angiogenin, ribonuclease, RNase A family, 5; angiogenin-1; epididymis luminal protein 168; HEL168; MGC22466; MGC71966; RAA1; Ribonuclease 5; ribonuclease A A1; ribonuclease A family member 5; RNase 5; RNASE4; RNASE5; Rnase5a
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA