product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
S100A8 Monoclonal Antibody (CF-145), eBioscience
catalog :
14-9745-82
quantity :
100 µg
price :
US 380.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
CF-145
reactivity :
human
application :
western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 9
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 2a
Kim J, Jeong J, Jung J, Jeon H, Lee S, Lim J, et al. Immunological characteristics and possible pathogenic role of urinary CD11c+ macrophages in lupus nephritis. Rheumatology (Oxford). 2020;: pubmed publisher
  • flow cytometry; human; fig 2a
Jeong J, Hong S, Kwon O, Ghang B, Hwang I, Kim Y, et al. CD14+ Cells with the Phenotype of Infiltrated Monocytes Consist of Distinct Populations Characterized by Anti-inflammatory as well as Pro-inflammatory Activity in Gouty Arthritis. Front Immunol. 2017;8:1260 pubmed publisher
Wu L, Xu Y, Zhao H, Zhou Y, Chen Y, Yang S, et al. FcγRIIB potentiates differentiation of myeloid-derived suppressor cells to mediate tumor immunoescape. Theranostics. 2022;12:842-858 pubmed publisher
Kiuru M, Kriner M, Wong S, Zhu G, Terrell J, Li Q, et al. High-Plex Spatial RNA Profiling Reveals Cell Type‒Specific Biomarker Expression during Melanoma Development. J Invest Dermatol. 2022;142:1401-1412.e20 pubmed publisher
Xu Z, Cheng C, Kong R, Liu Y, Wang S, Ma Y, et al. S100A8 and S100A9, both transcriptionally regulated by PU.1, promote epithelial-mesenchymal transformation (EMT) and invasive growth of dermal keratinocytes during scar formation post burn. Aging (Albany NY). 2021;13:15523-15537 pubmed publisher
Nadkarni S, Smith J, Sferruzzi Perri A, Ledwozyw A, Kishore M, Haas R, et al. Neutrophils induce proangiogenic T cells with a regulatory phenotype in pregnancy. Proc Natl Acad Sci U S A. 2016;113:E8415-E8424 pubmed publisher
Srikrishna G. S100A8 and S100A9: new insights into their roles in malignancy. J Innate Immun. 2012;4:31-40 pubmed publisher
Ehrchen J, Sunderkotter C, Foell D, Vogl T, Roth J. The endogenous Toll-like receptor 4 agonist S100A8/S100A9 (calprotectin) as innate amplifier of infection, autoimmunity, and cancer. J Leukoc Biol. 2009;86:557-66 pubmed publisher
Passey R, Xu K, Hume D, Geczy C. S100A8: emerging functions and regulation. J Leukoc Biol. 1999;66:549-56 pubmed
product information
Product Type :
Antibody
Product Name :
S100A8 Monoclonal Antibody (CF-145), eBioscience
Catalog # :
14-9745-82
Quantity :
100 µg
Price :
US 380.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Immunohistochemistry (Paraffin): 1 µg/mL, Western Blot: 5 µg/mL
Species :
Human
Clone :
CF-145
Isotype :
IgG2b, kappa
Storage :
4° C
Description :
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis.
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 1 µg/mL, Western Blot: 5 µg/mL
Aliases :
60B8AG; AI323541; B8Ag; CAGA; CAGB; calgranulin A; calgranulin B; calgranulin-A; Calgranulin-B; calprotectin L1H subunit; Calprotectin L1L subunit; CFAg; CGLA; CGLB; chemotactic cytokine CP-10; chemotactic S100 protein; CP-10; Cystic fibrosis antigen; L1Ag; leukocyte L1 complex heavy chain; Leukocyte L1 complex light chain; LIAG; MA387; MAC387; MIF; Migration inhibitory factor-related protein 14; migration inhibitory factor-related protein 8; MRP14; MRP-14; MRP8; MRP-8; NIF; P14; p8; Pro-inflammatory S100 cytokine; protein S100-A8; Protein S100-A9; S100 A8; S100 calcium binding protein A8; S100 calcium binding protein A8 (calgranulin A); S100 calcium binding protein A9; S100 calcium-binding protein A8; S100 calcium-binding protein A8 (calgranulin A); S100 calcium-binding protein A9; S100 calcium-binding protein A9 (calgranulin B); S100A8; S100A9; Urinary stone protein band A
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA