ZEB1 Monoclonal Antibody (3G6), eBioscience | Invitrogen 14-9741-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ZEB1 Monoclonal Antibody (3G6), eBioscience

catalog :

14-9741-82

quantity :

100 µg

price :

US 420.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3G6

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; mouse; loading ...; fig s4c	Sharon N, Chawla R, Mueller J, Vanderhooft J, Whitehorn L, Rosenthal B, et al. A Peninsular Structure Coordinates Asynchronous Differentiation with Morphogenesis to Generate Pancreatic Islets. Cell. 2019;176:790-804.e13 pubmed publisher
	Zhang S, Huangfu H, Zhao Q, Li Y, Wu L. Downregulation of long noncoding RNA HCP5/miR-216a-5p/ZEB1 axis inhibits the malignant biological function of laryngeal squamous cell carcinoma cells. Front Immunol. 2022;13:1022677 pubmed publisher
	L xf3 pez Moncada F, Torres M, Lavanderos B, Cerda O, Castell xf3 n E, Contreras H. SPARC Induces E-Cadherin Repression and Enhances Cell Migration through Integrin αvβ3 and the Transcription Factor ZEB1 in Prostate Cancer Cells. Int J Mol Sci. 2022;23: pubmed publisher
	Nath A, Ajit S, Sekar A, P R A, Muthusamy S. MicroRNA-200c/429 mediated regulation of Zeb1 augments N-Cadherin in mouse cardiac mesenchymal cells. Cell Biol Int. 2022;46:222-233 pubmed publisher
	López Moncada F, Torres M, Castellon E, Contreras H. Secreted protein acidic and rich in cysteine (SPARC) induces epithelial-mesenchymal transition, enhancing migration and invasion, and is associated with high Gleason score in prostate cancer. Asian J Androl. 2019;21:557-564 pubmed publisher
	Nakshatri H, Kumar B, Burney H, Cox M, Jacobsen M, Sandusky G, et al. Genetic Ancestry-dependent Differences in Breast Cancer-induced Field Defects in the Tumor-adjacent Normal Breast. Clin Cancer Res. 2019;25:2848-2859 pubmed publisher
	Wong T, Gao W, Chan J. Transcription regulation of E-cadherin by zinc finger E-box binding homeobox proteins in solid tumors. Biomed Res Int. 2014;2014:921564 pubmed publisher
	Wang J, Lee S, Teh C, Bunting K, Ma L, Shannon M. The transcription repressor, ZEB1, cooperates with CtBP2 and HDAC1 to suppress IL-2 gene activation in T cells. Int Immunol. 2009;21:227-35 pubmed publisher
	Burk U, Schubert J, Wellner U, Schmalhofer O, Vincan E, Spaderna S, et al. A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells. EMBO Rep. 2008;9:582-9 pubmed publisher

product information

Product Type :

Antibody

Product Name :

ZEB1 Monoclonal Antibody (3G6), eBioscience

Catalog # :

14-9741-82

Quantity :

100 µg

Price :

US 420.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 0.5 µg/mL, Immunohistochemistry (Paraffin): 10 µg/mL, Western Blot: 1 µg/mL

Species :

Human, Mouse, Rat

Clone :

3G6

Isotype :

IgG2a

Storage :

4° C

Description :

ZEB1 (Zinc finger E-box-binding homeobox 1) acts as a transcriptional repressor. It inhibits interleukin-2 (IL-2) gene expression. ZEB1 enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and depending on the cell type. It represses E-cadherin promoters and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. ZEB1 also represses BCL6 transcription in the presence of the corepressor CTBP1. It postively regulates neuronal differentiation and represses RCOR1 transcription activation during neurogenesis. Mutations in the gene can result in corneal dystrophy, posterior polymorphous and corneal dystrophy, Fuchs endothelial 6.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 0.5 µg/mL, Immunohistochemistry (Paraffin): 10 µg/mL, Western Blot: 1 µg/mL

Aliases :

[delta]EF1; 3110032K11Rik; AREB6; BZP; Delta EF1; delta-crystallin enhancer binding factor 1; deltaEF1; DELTA-EF1; FECD6; LOW QUALITY PROTEIN: zinc finger E-box-binding homeobox 1; MEB1; MGC133261; Negative regulator of IL2; Nil2; NIL2A; NIL-2A; NIL-2-A; NIL-2-A zinc finger protein; OTTHUMP00000019405; posterior polymorphous corneal dystrophy 3; PPCD3; RP11-472N13.4; Tcf18; TCF8; TCF-8; Transcription factor 8; transcription factor 8 (represses interleukin 2 expression); Tw; twirler; ZEB; Zeb1; Zfhep; Zfhx1a; Zfx1a; Zfx1ha; zinc finger E-box binding homeobox 1; zinc finger E-box-binding homeobox 1; Zinc finger homeobox protein 1a; zinc finger homeodomain enhancer-binding protein

more info or order :

Invitrogen product webpage