TdT Monoclonal Antibody (7UNA8U6), eBioscience | Invitrogen 14-9739-80 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TdT Monoclonal Antibody (7UNA8U6), eBioscience

catalog :

14-9739-80

quantity :

25 ug

price :

US 177.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7UNA8U6

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 5

Reference
Bristol J, Nelson S, Ohashi M, Casco A, Hayes M, Ranheim E, et al. Latent Epstein-Barr virus infection collaborates with Myc over-expression in normal human B cells to induce Burkitt-like Lymphomas in mice. PLoS Pathog. 2024;20:e1012132 pubmed publisher
Komori T, Okada A, Stewart V, Alt F. Lack of N regions in antigen receptor variable region genes of TdT-deficient lymphocytes. Science. 1993;261:1171-5 pubmed
Bollum F, Chang L. Immunological detection of a conserved structure for terminal deoxynucleotidyltransferase. J Biol Chem. 1981;256:8767-70 pubmed
McCaffrey R, Lillquist A, Sallan S, Cohen E, Osband M. Clinical utility of leukemia cell terminal transferase measurements. Cancer Res. 1981;41:4814-20 pubmed
Bogue M, Gilfillan S, Benoist C, Mathis D. Regulation of N-region diversity in antigen receptors through thymocyte differentiation and thymus ontogeny. Proc Natl Acad Sci U S A. 1992;89:11011-5 pubmed

product information

Product Type :

Antibody

Product Name :

TdT Monoclonal Antibody (7UNA8U6), eBioscience

Catalog # :

14-9739-80

Quantity :

25 ug

Price :

US 177.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

Immunohistochemistry (Paraffin): 10 ug/mL, Western Blot: 5 ug/mL

Species :

Human, Mouse, Rat

Clone :

7UNA8U6

Isotype :

IgG1, kappa

Storage :

4 C

Description :

Terminal Deoxynucleotidyl Transferase (TdT) is a DNA polymerase located in the cell nucleus which catalyses the polymerization of deoxynucleotides at the 3' hydroxyl ends of oligo or polydeoxynucleotide initiators and functions without a template. TdT is considered to be a highly specific marker for the diagnosis and classification of acute lymphoblastic lymphoma/leuksemias. The determination of TdT expression is most valuable when it is different to differentiate histologically between lymphoblastic lymphoma and Burkitt's lymphoma.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 10 ug/mL, Western Blot: 5 ug/mL

Aliases :

Deoxynucleotidyltransferase terminal; deoxynucleotidyltransferase, terminal; DNA nucleotidylexotransferase; Dntt; Nucleosidetriphosphate DNA Deoxynucleotidylexotransferase; nucleosidetriphosphate:DNA deoxynucleotidylexotransferase; TDT; Terminal addition enzyme; terminal deoxynucleotidyl transferase; terminal deoxynucleotidyltransferase; terminal deoxyribonucleotidyltransferase; terminal transferase