RAB5A Monoclonal Antibody (2E8B11), eBioscience | Invitrogen 14-9711-82 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

RAB5A Monoclonal Antibody (2E8B11), eBioscience

catalog :

14-9711-82

quantity :

100 ug

price :

US 471.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2E8B11

reactivity :

human

application :

western blot, immunocytochemistry, immunoprecipitation

product information

Product Type :

Antibody

Product Name :

RAB5A Monoclonal Antibody (2E8B11), eBioscience

Catalog # :

14-9711-82

Quantity :

100 ug

Price :

US 471.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Immunocytochemistry: 1:100, Immunoprecipitation: Assay-dependent, Western Blot: 1:1,000

Species :

Human

Clone :

2E8B11

Isotype :

IgG1, kappa

Storage :

4 C

Description :

RAB5 are among the small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulation of filopodia extension. Required for the exosomal release of SDCBP, CD63, PDCD6IP and syndecan. Regulates maturation of apoptotic cell-containing phagosomes, probably downstream of DYN2 and PIK3C3.

Immunogen :

Purified recombinant fragment of human Rab5a (AA: 1-215) expressed in E. Coli.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100, Immunoprecipitation: Assay-dependent, Western Blot: 1:1,000

Aliases :

2410015H04Rik; AI663973; AU021172; nnyRab5a; Rab 5; Rab 5A; RAB5; RAB5A; RAB5A, member RAS oncogene family; Ras related protein; RAS-associated protein RAB5A; ras-related protein Rab-5A; Small GTP-binding protein rab5