This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
PAR2 Monoclonal Antibody (SAM11), eBioscience
catalog :
14-9699-82
quantity :
100 ug
price :
US 376.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
SAM11

The same clone is also sold as:
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
citations: 7
Reference
Sitaras N, Rivera J, Noueihed B, Bien Aimé M, Zaniolo K, Omri S, et al. Retinal neurons curb inflammation and enhance revascularization in ischemic retinopathies via proteinase-activated receptor-2. Am J Pathol. 2015;185:581-95 pubmed publisher
Adams M, Pagel C, Mackie E, Hooper J. Evaluation of antibodies directed against human protease-activated receptor-2. Naunyn Schmiedebergs Arch Pharmacol. 2012;385:861-73 pubmed publisher
Arizmendi N, Abel M, Puttagunta L, Asaduzzaman M, Davidson C, Karimi K, et al. Mucosal exposure to cockroach extract induces allergic sensitization and allergic airway inflammation. Allergy Asthma Clin Immunol. 2011;7:22 pubmed publisher
Frateschi S, Camerer E, Crisante G, Rieser S, Membrez M, Charles R, et al. PAR2 absence completely rescues inflammation and ichthyosis caused by altered CAP1/Prss8 expression in mouse skin. Nat Commun. 2011;2:161 pubmed
Kaufmann R, Oettel C, Horn A, Halbhuber K, Eitner A, Krieg R, et al. Met receptor tyrosine kinase transactivation is involved in proteinase-activated receptor-2-mediated hepatocellular carcinoma cell invasion. Carcinogenesis. 2009;30:1487-96 pubmed publisher
Bocheva G, Rattenholl A, Kempkes C, Goerge T, Lin C, D Andrea M, et al. Role of matriptase and proteinase-activated receptor-2 in nonmelanoma skin cancer. J Invest Dermatol. 2009;129:1816-23 pubmed publisher
Buddenkotte J, Stroh C, Engels I, Moormann C, Shpacovitch V, Seeliger S, et al. Agonists of proteinase-activated receptor-2 stimulate upregulation of intercellular cell adhesion molecule-1 in primary human keratinocytes via activation of NF-kappa B. J Invest Dermatol. 2005;124:38-45 pubmed
product information
Product Type :
Antibody
Product Name :
PAR2 Monoclonal Antibody (SAM11), eBioscience
Catalog # :
14-9699-82
Quantity :
100 ug
Price :
US 376.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
ELISA: Assay-Dependent, Functional Assay: Assay-Dependent, Immunocytochemistry: 10 ug/mL, Immunohistochemistry (Paraffin): 10 ug/mL, Western Blot: 1:250
Species :
Human
Clone :
SAM11
Isotype :
IgG2a, kappa
Storage :
4 C
Description :
Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83% identical to the mouse receptor sequence.
Format :
Liquid
Applications w/Dilutions :
ELISA: Assay-Dependent, Functional Assay: Assay-Dependent, Immunocytochemistry: 10 ug/mL, Immunohistochemistry (Paraffin): 10 ug/mL, Western Blot: 1:250
Aliases :
coagulation factor II (thrombin) receptor-like 1; coagulation factor II receptor-like 1; F2R like trypsin receptor 1; F2RL1; Gpcr11; Gpr11; G-protein coupled receptor 11; PAR2; PAR-2; protease-activated receptor 2; Protease-activated receptor-2; proteinase-activated receptor 2; Proteinase-activated receptor 2, alternate cleaved 1; Proteinase-activated receptor 2, alternate cleaved 2; proteinase-activated receptor-2; Proteinase-activated receptor-2 G protein-coupled receptor 11; Proteinase-activated receptor-2, G protein-coupled receptor 11; thrombin receptor-like 1
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA