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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
ALDH1L1 Monoclonal Antibody (7G8), eBioscience
catalog :
14-9595-82
quantity :
100 ug
price :
US 403.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
7G8
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 6
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; 1:100; fig 4
Chen A, Akinyemi R, Hase Y, Firbank M, Ndung u M, Foster V, et al. Frontal white matter hyperintensities, clasmatodendrosis and gliovascular abnormalities in ageing and post-stroke dementia. Brain. 2016;139:242-58 pubmed publisher
Hase Y, Chen A, Bates L, Craggs L, Yamamoto Y, Gemmell E, et al. Severe white matter astrocytopathy in CADASIL. Brain Pathol. 2018;28:832-843 pubmed publisher
Barreto G, Sun X, Xu L, Giffard R. Astrocyte proliferation following stroke in the mouse depends on distance from the infarct. PLoS ONE. 2011;6:e27881 pubmed publisher
Oleinik N, Krupenko N, Krupenko S. Epigenetic Silencing of ALDH1L1, a Metabolic Regulator of Cellular Proliferation, in Cancers. Genes Cancer. 2011;2:130-9 pubmed publisher
Cahoy J, Emery B, Kaushal A, Foo L, Zamanian J, Christopherson K, et al. A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function. J Neurosci. 2008;28:264-78 pubmed publisher
Neymeyer V, Tephly T, Miller M. Folate and 10-formyltetrahydrofolate dehydrogenase (FDH) expression in the central nervous system of the mature rat. Brain Res. 1997;766:195-204 pubmed
product information
Product Type :
Antibody
Product Name :
ALDH1L1 Monoclonal Antibody (7G8), eBioscience
Catalog # :
14-9595-82
Quantity :
100 ug
Price :
US 403.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: Assay-Dependent, Immunocytochemistry: Assay-Dependent, Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: Assay-Dependent
Species :
Human
Clone :
7G8
Isotype :
IgG2b, kappa
Storage :
4 C
Description :
ALDH1L1 catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family and is responsible for formate oxidation in vivo. Deficiencies in this gene can result in an accumulation of formate and subsequent methanol poisoning.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: Assay-Dependent, Immunocytochemistry: Assay-Dependent, Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: Assay-Dependent
Aliases :
10-formyltetrahydrofolate dehydrogenase; 10fTHF; 10-fTHF; 10FTHFDH; 10-FTHFDH; 1810048F20Rik; aldehyde dehydrogenase 1 family member L1; aldehyde dehydrogenase 1 family, member L1; aldehyde dehydrogenase family 1 member L1; Aldh1l1; Cytosolic 10-formyltetrahydrofolate dehydrogenase; DKFZp781N0997; FBP-CI; FDH; formyltetrahydrofolate dehydrogenase; Fthfd; LOC100855730; MER57B-ALDH1L1; Neut2
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA