CD321 (F11R) Monoclonal Antibody (WK9), eBioscience | Invitrogen 14-9321-82 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD321 (F11R) Monoclonal Antibody (WK9), eBioscience

catalog :

14-9321-82

quantity :

100 ug

price :

US 265.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

WK9

reactivity :

human

application :

western blot, immunocytochemistry, immunoprecipitation, flow cytometry

citations: 3

Reference
Naik M, Mousa S, Parkos C, Naik U. Signaling through JAM-1 and alphavbeta3 is required for the angiogenic action of bFGF: dissociation of the JAM-1 and alphavbeta3 complex. Blood. 2003;102:2108-14 pubmed
Ostermann G, Weber K, Zernecke A, Schröder A, Weber C. JAM-1 is a ligand of the beta(2) integrin LFA-1 involved in transendothelial migration of leukocytes. Nat Immunol. 2002;3:151-8 pubmed
Sobocka M, Sobocki T, Banerjee P, Weiss C, Rushbrook J, Norin A, et al. Cloning of the human platelet F11 receptor: a cell adhesion molecule member of the immunoglobulin superfamily involved in platelet aggregation. Blood. 2000;95:2600-9 pubmed

product information

Product Type :

Antibody

Product Name :

CD321 (F11R) Monoclonal Antibody (WK9), eBioscience

Catalog # :

14-9321-82

Quantity :

100 ug

Price :

US 265.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 0.25 ug/test, Immunocytochemistry: 5 ug/ml, Immunoprecipitation: Assay-Dependent, Western Blot: 1 ug/ml

Species :

Human

Clone :

WK9

Isotype :

IgG1, kappa

Storage :

4 C

Description :

CD321 (F11R, JAM-1, JAM-A) is a cell-surface adhesion molecule belonging to the Ig superfamily of receptors. CD321 is a 32-41 kD glycoprotein, possessing two extracellular Ig-like domains, a transmembrane region, and a short cytosolic tail. The protein assembles at the membrane as a homodimer, and can associate laterally with other membrane proteins including integrins. CD321 is expressed on a variety of cell types, including leukocytes, platelets, erythrocytes, stem cells, epithelial and endothelial cells, and plays a role in mediating cell-cell contact. CD321 can be found in close proximity to several components of epithelial tight junctions, including ZO-1 and occludin. CD321 is involved in the maintenance of epithelial and endothelial barriers, hematopoiesis, angiogenesis, and tumor proliferation, invasion, and metastasis.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.25 ug/test, Immunocytochemistry: 5 ug/ml, Immunoprecipitation: Assay-Dependent, Western Blot: 1 ug/ml

Aliases :

9130004G24; AA638916; BV11 antigen; CD321; ESTM33; F11 R; F11 receptor; F11 receptor/F11R; F11R; JAM; JAM1; JAM-1; JAMA; JAM-A; Jcam; Jcam1; junction cell adhesion molecule A; junction cell adhesion molecule1; junctional adhesion molecule 1; Junctional adhesion molecule A; KAT; Ly106; PAM-1; Platelet adhesion molecule 1; platelet F11 receptor; UNQ264/PRO301