CD200 Monoclonal Antibody (OX104), eBioscience™ | Invitrogen 14-9200-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD200 Monoclonal Antibody (OX104), eBioscience™

catalog :

14-9200-82

quantity :

100 µg

price :

120 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

OX104

reactivity :

African green monkey, human

application :

immunohistochemistry, flow cytometry, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; fig 8	Jourdan M, Cren M, Schafer P, Robert N, Duperray C, Vincent L, et al. Differential effects of lenalidomide during plasma cell differentiation. Oncotarget. 2016;7:28096-111 pubmed publisher
flow cytometry; African green monkey; loading ...; fig s1c	Hong J, Amancha P, Rogers K, Courtney C, Havenar Daughton C, Crotty S, et al. Early lymphoid responses and germinal center formation correlate with lower viral load set points and better prognosis of simian immunodeficiency virus infection. J Immunol. 2014;193:797-806 pubmed publisher
	Liu J, Talebian F, Wu L, Liu Z, Li M, Wu L, et al. A Critical Role for CD200R Signaling in Limiting the Growth and Metastasis of CD200+ Melanoma. J Immunol. 2016;197:1489-97 pubmed publisher
	Turaç G, Hindley C, Thomas R, Davis J, Deleidi M, Gasser T, et al. Combined flow cytometric analysis of surface and intracellular antigens reveals surface molecule markers of human neuropoiesis. PLoS ONE. 2013;8:e68519 pubmed publisher
	Caraux A, Vincent L, Bouhya S, Quittet P, Moreaux J, Requirand G, et al. Residual malignant and normal plasma cells shortly after high dose melphalan and stem cell transplantation. Highlight of a putative therapeutic window in Multiple Myeloma?. Oncotarget. 2012;3:1335-47 pubmed
	Li Y, Zhao L, Tong L, Qian S, Ren Y, Zhang L, et al. Aberrant CD200/CD200R1 expression and function in systemic lupus erythematosus contributes to abnormal T-cell responsiveness and dendritic cell activity. Arthritis Res Ther. 2012;14:R123 pubmed publisher
	van Dongen J, Lhermitte L, Bottcher S, Almeida J, van der Velden V, Flores Montero J, et al. EuroFlow antibody panels for standardized n-dimensional flow cytometric immunophenotyping of normal, reactive and malignant leukocytes. Leukemia. 2012;26:1908-75 pubmed publisher
	Schoenhals M, Frecha C, Bruyer A, Caraux A, Veyrune J, Jourdan M, et al. Efficient transduction of healthy and malignant plasma cells by lentiviral vectors pseudotyped with measles virus glycoproteins. Leukemia. 2012;26:1663-70 pubmed publisher
	Letarte M, Voulgaraki D, Hatherley D, Foster Cuevas M, Saunders N, Barclay A. Analysis of leukocyte membrane protein interactions using protein microarrays. BMC Biochem. 2005;6:2 pubmed
	Foster Cuevas M, Wright G, Puklavec M, Brown M, Barclay A. Human herpesvirus 8 K14 protein mimics CD200 in down-regulating macrophage activation through CD200 receptor. J Virol. 2004;78:7667-76 pubmed
	Wright G, Cherwinski H, Foster Cuevas M, Brooke G, Puklavec M, Bigler M, et al. Characterization of the CD200 receptor family in mice and humans and their interactions with CD200. J Immunol. 2003;171:3034-46 pubmed

product information

Product Type :

Antibody

Product Name :

CD200 Monoclonal Antibody (OX104), eBioscience™

Catalog # :

14-9200-82

Quantity :

100 µg

Price :

120 USD

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 0.25 µg/test, Immunohistochemistry (Frozen): Assay-Dependent

Species :

Human

Clone :

OX104

Isotype :

IgG1, kappa

Storage :

4° C

Description :

CD200 is a type-1 membrane glycoprotein that contains two immunoglobulin domains, and belongs to the immunoglobulin superfamily. CD200 is a broadly distributed cell surface glycoprotein that interacts with a receptor on myeloid cells (CD200R) and is implicated in locally preventing macrophage activation. Distant, but recognizable, homologues of CD200 have been identified in many herpesviruses and poxviruses. Studies of the related genes in mouse and rat suggest that CD200 may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms of CD200 have been found. Diseases associated with CD200 dysfunction include Mantle Cell Lymphoma and Primary Hypertrophic Osteoarthropathy.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.25 µg/test, Immunohistochemistry (Frozen): Assay-Dependent

Aliases :

antigen identified by monoclonal antibody MRC OX-2; CD200; CD200 antigen; CD200 molecule; cell surface protein (thymocyte antigen identified by monoclonal antibody MRC-OX2); Cspmo2; MOX1; MOX2; MRC; MRC OX-2 antigen; MRCOX2; My033; OX2; OX-2; OX-2 membrane glycoprotein

more info or order :

Invitrogen product webpage