This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Fc Receptor Binding Inhibitor Polyclonal Antibody, eBioscience
catalog :
14-9161-71
quantity :
25 Tests
price :
US 110.00
clonality :
polyclonal
conjugate :
nonconjugated
reactivity :
human
application :
flow cytometry
citations: 62
Reference
Hoving D, Marques A, Huisman W, Nosoh B, de Kroon A, van Hengel O, et al. Combinatorial multimer staining and spectral flow cytometry facilitate quantification and characterization of polysaccharide-specific B cell immunity. Commun Biol. 2023;6:1095 pubmed publisher
Fitzsimons S, Mu xf1 oz San Mart xed n M, Nally F, Dillon E, Fashina I, Strowitzki M, et al. Inhibition of pro-inflammatory signaling in human primary macrophages by enhancing arginase-2 via target site blockers. Mol Ther Nucleic Acids. 2023;33:941-959 pubmed publisher
Ruder A, Temmerman L, van Dommelen J, Nagenborg J, Lu C, Sluimer J, et al. Culture density influences the functional phenotype of human macrophages. Front Immunol. 2023;14:1078591 pubmed publisher
Adzika G, Mprah R, Rizvi R, Adekunle A, Ndzie Noah M, Wowui P, et al. Occlusion preconditioned mice are resilient to hypobaric hypoxia-induced myocarditis and arrhythmias due to enhanced immunomodulation, metabolic homeostasis, and antioxidants defense. Front Immunol. 2023;14:1124649 pubmed publisher
Yang H, Gao Y, Xu D, Xu K, Liang S, Yang Z, et al. MEK1 drives oncogenic signaling and interacts with PARP1 for genomic and metabolic homeostasis in malignant pleural mesothelioma. Cell Death Discov. 2023;9:55 pubmed publisher
Ismailova A, Salehi Tabar R, Dimitrov V, Memari B, Barbier C, White J. Identification of a forkhead box protein transcriptional network induced in human neutrophils in response to inflammatory stimuli. Front Immunol. 2023;14:1123344 pubmed publisher
Wu B, Qi L, Chiang H, Pan H, Zhang X, Greenbaum A, et al. BRCA1 deficiency in mature CD8+ T lymphocytes impairs antitumor immunity. J Immunother Cancer. 2023;11: pubmed publisher
Sanson R, Lazzara S, Cune D, Pitasi C, Trentesaux C, Fraudeau M, et al. Axin1 Protects Colon Carcinogenesis by an Immune-Mediated Effect. Cell Mol Gastroenterol Hepatol. 2023;15:689-715 pubmed publisher
Fatehi Hassanabad A, Schoettler F, Kent W, Adams C, Holloway D, Ali I, et al. Comprehensive characterization of the postoperative pericardial inflammatory response: Potential implications for clinical outcomes. JTCVS Open. 2022;12:118-136 pubmed publisher
Pushparaj P, Nicoletto A, Sheward D, Das H, Castro Dopico X, Perez Vidakovics L, et al. Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies. Immunity. 2022;: pubmed publisher
Morrow R, Allam A, Konecnik J, Baloyan D, Dijkstra C, Eissmann M, et al. Tumor Growth Remains Refractory to Myc Ablation in Host Macrophages. Cells. 2022;11: pubmed publisher
Miatello J, Lukaszewicz A, Carter M, Faivre V, Hua S, Martinet K, et al. CIITA promoter polymorphism impairs monocytes HLA-DR expression in patients with septic shock. iScience. 2022;25:105291 pubmed publisher
Petrie Hanson L, Peterman A. Trained Immunity Provides Long-Term Protection against Bacterial Infections in Channel Catfish. Pathogens. 2022;11: pubmed publisher
Dossybayeva K, Bexeitov Y, Mukusheva Z, Almukhamedova Z, Assylbekova M, Abdukhakimova D, et al. Analysis of Peripheral Blood Basophils in Pediatric Systemic Lupus Erythematosus. Diagnostics (Basel). 2022;12: pubmed publisher
Tomasek K, Leithner A, Glatzova I, Lukesch M, Guet C, Sixt M. Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to CD14. elife. 2022;11: pubmed publisher
Poh A, Love C, Chisanga D, Steer J, Baloyan D, Chopin M, et al. Therapeutic inhibition of the SRC-kinase HCK facilitates T cell tumor infiltration and improves response to immunotherapy. Sci Adv. 2022;8:eabl7882 pubmed publisher
Wilkes M, Scanlon V, Shibuya A, Cepika A, Eskin A, Chen Z, et al. Downregulation of SATB1 by miRNAs reduces megakaryocyte/erythroid progenitor expansion in preclinical models of Diamond-Blackfan anemia. Exp Hematol. 2022;111:66-78 pubmed publisher
Nemeth D, Liu X, McKim D, DiSabato D, Oliver B, Herd A, et al. Dynamic Interleukin-1 Receptor Type 1 Signaling Mediates Microglia-Vasculature Interactions Following Repeated Systemic LPS. J Inflamm Res. 2022;15:1575-1590 pubmed publisher
Essien E, Hofer T, Atkinson M, Anastasov N. Combining HDAC and MEK Inhibitors with Radiation against Glioblastoma-Derived Spheres. Cells. 2022;11: pubmed publisher
Vorkas C, Krishna C, Li K, AUBE J, Fitzgerald D, Mazutis L, et al. Single-Cell Transcriptional Profiling Reveals Signatures of Helper, Effector, and Regulatory MAIT Cells during Homeostasis and Activation. J Immunol. 2022;208:1042-1056 pubmed publisher
Li B, Maslan A, Kitayama S, Pierce C, Streets A, Sohn L. Mechanical phenotyping reveals unique biomechanical responses in retinoic acid-resistant acute promyelocytic leukemia. iScience. 2022;25:103772 pubmed publisher
Yin H, Karayel Ö, Chao Y, Seeholzer T, Hamp I, Plettenburg O, et al. A20 and ABIN-1 cooperate in balancing CBM complex-triggered NF-κB signaling in activated T cells. Cell Mol Life Sci. 2022;79:112 pubmed publisher
Miedema A, Gerrits E, Brouwer N, Jiang Q, Kracht L, Meijer M, et al. Brain macrophages acquire distinct transcriptomes in multiple sclerosis lesions and normal appearing white matter. Acta Neuropathol Commun. 2022;10:8 pubmed publisher
Lu D, Wei J, Chen J, Zhao J, Wang J, Gong Y, et al. Apelin Alleviates Meniscus Endothelial Cell Apoptosis in Osteoarthritis. Dis Markers. 2022;2022:3556372 pubmed publisher
Rujas E, Cui H, Burnie J, Aschner C, Zhao T, Insausti S, et al. Engineering pan-HIV-1 neutralization potency through multispecific antibody avidity. Proc Natl Acad Sci U S A. 2022;119: pubmed publisher
Lee H, Sun R, Niehrs C. Uncoupling the BMP receptor antagonist function from the WNT agonist function of R-spondin 2 using the inhibitory peptide dendrimer RWd. J Biol Chem. 2022;298:101586 pubmed publisher
Timmerman R, Zuiderwijk Sick E, Oosterhof N, t Jong A, Veth J, Burm S, et al. Transcriptome analysis reveals the contribution of oligodendrocyte and radial glia-derived cues for maintenance of microglia identity. Glia. 2022;70:728-747 pubmed publisher
Huang Q, Lam A, Boardman D, Dawson N, Levings M. Suppression of Human Dendritic Cells by Regulatory T Cells. Bio Protoc. 2021;11:e4217 pubmed publisher
Chang P, Wang H, Kuo Y, Lee L, Liao C, Kuo H, et al. Circulating p16-Positive and p16-Negative Tumor Cells Serve as Independent Prognostic Indicators of Survival in Patients with Head and Neck Squamous Cell Carcinomas. J Pers Med. 2021;11: pubmed publisher
Ummarino S, Hausman C, Gaggi G, Rinaldi L, Bassal M, Zhang Y, et al. NAD Modulates DNA Methylation and Cell Differentiation. Cells. 2021;10: pubmed publisher
Yang F, Zhao J, Luo X, Li T, Wang Z, Wei Q, et al. Transcriptome Profiling Reveals B-Lineage Cells Contribute to the Poor Prognosis and Metastasis of Clear Cell Renal Cell Carcinoma. Front Oncol. 2021;11:731896 pubmed publisher
Sun R, He L, Lee H, Glinka A, Andresen C, Hübschmann D, et al. RSPO2 inhibits BMP signaling to promote self-renewal in acute myeloid leukemia. Cell Rep. 2021;36:109559 pubmed publisher
Wilkes M, Jung K, Lee B, Saxena M, Sathianathen R, Mercado J, et al. The active component of ginseng, ginsenoside Rb1, improves erythropoiesis in models of Diamond-Blackfan anemia by targeting Nemo-like kinase. J Biol Chem. 2021;297:100988 pubmed publisher
Mogilenko D, Caiazzo R, L homme L, Pineau L, Raverdy V, Noulette J, et al. IFNγ-producing NK cells in adipose tissue are associated with hyperglycemia and insulin resistance in obese women. Int J Obes (Lond). 2021;45:1607-1617 pubmed publisher
Li Y, Sun Y, Kulke M, Hechler T, Van der Jeught K, Dong T, et al. Targeted immunotherapy for HER2-low breast cancer with 17p loss. Sci Transl Med. 2021;13: pubmed publisher
Webb L, Fra Bido S, Innocentin S, Matheson L, Attaf N, Bignon A, et al. Ageing promotes early T follicular helper cell differentiation by modulating expression of RBPJ. Aging Cell. 2021;20:e13295 pubmed publisher
Goldenson B, Zhu H, Wang Y, Heragu N, Bernareggi D, Ruiz Cisneros A, et al. Umbilical Cord Blood and iPSC-Derived Natural Killer Cells Demonstrate Key Differences in Cytotoxic Activity and KIR Profiles. Front Immunol. 2020;11:561553 pubmed publisher
Liu S, Grantham A, Landry C, Granda B, Chopra R, Chakravarthy S, et al. A CRISPR Screen Reveals Resistance Mechanisms to CD3-Bispecific Antibody Therapy. Cancer Immunol Res. 2021;9:34-49 pubmed publisher
Osinski C, Le Gl xe9 au L, Poitou C, de Toro Martín J, Genser L, Fradet M, et al. Type 2 diabetes is associated with impaired jejunal enteroendocrine GLP-1 cell lineage in human obesity. Int J Obes (Lond). 2021;45:170-183 pubmed publisher
Wilkes M, Siva K, Chen J, Varetti G, Youn M, Chae H, et al. Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase. Nat Commun. 2020;11:3344 pubmed publisher
Wang S, Mustafa M, Yuede C, SALAZAR S, Kong P, Long H, et al. Anti-human TREM2 induces microglia proliferation and reduces pathology in an Alzheimer's disease model. J Exp Med. 2020;217: pubmed publisher
Zhu H, Blum R, Bernareggi D, Ask E, Wu Z, Hoel H, et al. Metabolic Reprograming via Deletion of CISH in Human iPSC-Derived NK Cells Promotes In Vivo Persistence and Enhances Anti-tumor Activity. Cell Stem Cell. 2020;27:224-237.e6 pubmed publisher
Davenne T, Klintman J, Sharma S, Rigby R, Blest H, Cursi C, et al. SAMHD1 Limits the Efficacy of Forodesine in Leukemia by Protecting Cells against the Cytotoxicity of dGTP. Cell Rep. 2020;31:107640 pubmed publisher
Samarani S, Sagala P, Jantchou P, Grimard G, Faure C, Deslandres C, et al. Phenotypic and Functional Changes in Peripheral Blood Natural Killer Cells in Crohn Disease Patients. Mediators Inflamm. 2020;2020:6401969 pubmed publisher
Langenberg M, Hoogerwerf M, Koopman J, Janse J, Kos van Oosterhoud J, Feijt C, et al. A controlled human Schistosoma mansoni infection model to advance novel drugs, vaccines and diagnostics. Nat Med. 2020;26:326-332 pubmed publisher
Pedicone C, Fernandes S, Dungan O, Dormann S, Viernes D, Adhikari A, et al. Pan-SHIP1/2 inhibitors promote microglia effector functions essential for CNS homeostasis. J Cell Sci. 2020;133: pubmed publisher
Bagwell C, Inokuma M, Hunsberger B, Herbert D, Bray C, Hill B, et al. Automated Data Cleanup for Mass Cytometry. Cytometry A. 2020;97:184-198 pubmed publisher
Deniset J, Belke D, Lee W, Jorch S, Deppermann C, Hassanabad A, et al. Gata6+ Pericardial Cavity Macrophages Relocate to the Injured Heart and Prevent Cardiac Fibrosis. Immunity. 2019;51:131-140.e5 pubmed publisher
Sorensen J, Kaluhiokalani J, Hafen P, Deyhle M, Parcell A, Hyldahl R. An altered response in macrophage phenotype following damage in aged human skeletal muscle: implications for skeletal muscle repair. FASEB J. 2019;33:10353-10368 pubmed publisher
Rosen D, Seki S, Fernandez Castaneda A, Beiter R, Eccles J, Woodfolk J, et al. Modulation of the sigma-1 receptor-IRE1 pathway is beneficial in preclinical models of inflammation and sepsis. Sci Transl Med. 2019;11: pubmed publisher
Triplett K, Pokhrel S, Castleman M, Daly S, Elmore B, Joyner J, et al. GPER activation protects against epithelial barrier disruption by Staphylococcus aureus α-toxin. Sci Rep. 2019;9:1343 pubmed publisher
Boyd A, Aslostovar L, Reid J, Ye W, Tanasijevic B, Porras D, et al. Identification of Chemotherapy-Induced Leukemic-Regenerating Cells Reveals a Transient Vulnerability of Human AML Recurrence. Cancer Cell. 2018;34:483-498.e5 pubmed publisher
Sponaas A, Yang R, Rustad E, Standal T, Thoresen A, Dao Vo C, et al. PD1 is expressed on exhausted T cells as well as virus specific memory CD8+ T cells in the bone marrow of myeloma patients. Oncotarget. 2018;9:32024-32035 pubmed publisher
Zhu B, Tang L, Chen S, Yin C, Peng S, Li X, et al. Targeting the upstream transcriptional activator of PD-L1 as an alternative strategy in melanoma therapy. Oncogene. 2018;37:4941-4954 pubmed publisher
Habib S, El Andaloussi A, Elmasry K, Handoussa A, Azab M, Elsawey A, et al. PDL-1 Blockade Prevents T Cell Exhaustion, Inhibits Autophagy, and Promotes Clearance of Leishmania donovani. Infect Immun. 2018;86: pubmed publisher
Grasse M, Rosenkrands I, Olsen A, Follmann F, Dietrich J. A flow cytometry-based assay to determine the phagocytic activity of both clinical and nonclinical antibody samples against Chlamydia trachomatis. Cytometry A. 2018;93:525-532 pubmed publisher
Miao X, Xu R, Fan B, Chen J, Li X, Mao W, et al. PD-L1 reverses depigmentation in Pmel-1 vitiligo mice by increasing the abundance of Tregs in the skin. Sci Rep. 2018;8:1605 pubmed publisher
Liu W, Li T, Wang P, Liu W, Liu F, Mo X, et al. LRRC25 plays a key role in all-trans retinoic acid-induced granulocytic differentiation as a novel potential leukocyte differentiation antigen. Protein Cell. 2018;9:785-798 pubmed publisher
Montler R, Bell R, Thalhofer C, Leidner R, Feng Z, Fox B, et al. OX40, PD-1 and CTLA-4 are selectively expressed on tumor-infiltrating T cells in head and neck cancer. Clin Transl Immunology. 2016;5:e70 pubmed publisher
Hollmen M, Karaman S, Schwager S, Lisibach A, Christiansen A, Maksimow M, et al. G-CSF regulates macrophage phenotype and associates with poor overall survival in human triple-negative breast cancer. Oncoimmunology. 2016;5:e1115177 pubmed
Lindsay S, Johnstone S, McGrath M, Mallinson D, Barnett S. Comparative miRNA-Based Fingerprinting Reveals Biological Differences in Human Olfactory Mucosa- and Bone-Marrow-Derived Mesenchymal Stromal Cells. Stem Cell Reports. 2016;6:729-742 pubmed publisher
Han L, Qiu P, Zeng Z, Jorgensen J, Mak D, Burks J, et al. Single-cell mass cytometry reveals intracellular survival/proliferative signaling in FLT3-ITD-mutated AML stem/progenitor cells. Cytometry A. 2015;87:346-56 pubmed publisher
product information
Product Type :
Antibody
Product Name :
Fc Receptor Binding Inhibitor Polyclonal Antibody, eBioscience
Catalog # :
14-9161-71
Quantity :
25 Tests
Price :
US 110.00
Clonality :
Polyclonal
Purity :
Affinity chromatography
Reactivity :
Human
Applications :
Flow Cytometry: 20 uL/test
Species :
Human
Storage :
4 C
Description :
Four different classes of Fcy receptors have been identified: FcyRI (CD64), FcyRII (CD32), and FcyRIII (CD16), and they are expressed at varying levels in multiple cell lineages including high expression in myeloid, granulocyte and B cells. The biological function of the FcyR, including initiation of endocytosis, phagocytosis and antigen presentation, is elicited upon binding of host-immunoglobulin. The extent to which mouse monoclonal antibodies will bind to human FcyR varies depending on the isotype of the monoclonal antibody. Furthermore, different monoclonal antibodies of the same isotype will display different binding to human FcyRs.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 20 uL/test
Aliases :
Fc blocking; FcR BI; FcR Inhibitor
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA