HSP27 Monoclonal Antibody (STRSN), eBioscience | Invitrogen 14-9112-80 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

HSP27 Monoclonal Antibody (STRSN), eBioscience

catalog :

14-9112-80

quantity :

25 ug

price :

US 156.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

STRSN

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 4

Reference
Straume O, Shimamura T, Lampa M, Carretero J, yan A, Jia D, et al. Suppression of heat shock protein 27 induces long-term dormancy in human breast cancer. Proc Natl Acad Sci U S A. 2012;109:8699-704 pubmed publisher
Wood K, Voss O, Huang Q, Parihar A, Mehta N, Batra S, et al. The small heat shock protein 27 is a key regulator of CD8+ CD57+ lymphocyte survival. J Immunol. 2010;184:5582-8 pubmed publisher
Srivastava P. Roles of heat-shock proteins in innate and adaptive immunity. Nat Rev Immunol. 2002;2:185-94 pubmed
Landry J, Lambert H, Zhou M, Lavoie J, Hickey E, Weber L, et al. Human HSP27 is phosphorylated at serines 78 and 82 by heat shock and mitogen-activated kinases that recognize the same amino acid motif as S6 kinase II. J Biol Chem. 1992;267:794-803 pubmed

product information

Product Type :

Antibody

Product Name :

HSP27 Monoclonal Antibody (STRSN), eBioscience

Catalog # :

14-9112-80

Quantity :

25 ug

Price :

US 156.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: Assay-Dependent, Immunocytochemistry: 1-2.5 ug/mL, Immunohistochemistry (Paraffin): 1 ug/mL, Western Blot: 1 ug/mL

Species :

Human

Clone :

STRSN

Isotype :

IgG1, kappa

Storage :

4 C

Description :

In response to adverse changes in their environment, cells from many organisms increase the expression of a class of proteins referred to as heat shock or stress proteins. HSPB1 (heat shock protein beta-1 or HSP27) is a small heat shock protein which functions as a molecular chaperone that maintains denatured proteins in a folding-competent state. It plays a role in stress resistance and actin organization. Through its molecular chaperone activity, HSP27 regulates numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins. Mutations in the gene can result in Charcot-Marie-Tooth disease 2F and Neuronopathy distal hereditary motor 2B.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-Dependent, Immunocytochemistry: 1-2.5 ug/mL, Immunohistochemistry (Paraffin): 1 ug/mL, Western Blot: 1 ug/mL

Aliases :

27kDa; 28 kDa heat shock protein; CMT2F; DKFZp586P1322; epididymis secretory protein Li 102; estrogen-regulated 24 kDa protein; Growth-related 25 kDa protein; heat shock 25 kDa protein; Heat shock 27 kDa protein; heat shock 27kD protein 1; heat shock 27kDa protein 1; Heat shock protein; heat shock protein 1; heat shock protein 27 kDa beta-1; heat shock protein B1; heat shock protein beta-1; heat shock protein family B (small) member 1; heat shock protein, 25 kDa; heat-shock protein; HEL-S-102; HMN2B; HS; HS.76067; HSP; HSP 25; HSP 27; Hsp25; HSP27; HSP28; HSPB1; p25; Phospho-HSP 27; SRP27; Stress-responsive protein 27; truncated hsp25