CD289 (TLR9) Monoclonal Antibody (M9.D6), eBioscience | Invitrogen 14-9093-95 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD289 (TLR9) Monoclonal Antibody (M9.D6), eBioscience

catalog :

14-9093-95

quantity :

10 mg

price :

US 3685.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

M9.D6

reactivity :

mouse

application :

western blot, flow cytometry

citations: 7

Reference
Derkow K, KrÃ¼ger C, Dembny P, Lehnardt S. Microglia Induce Neurotoxic IL-17+ Î³Î´ T Cells Dependent on TLR2, TLR4, and TLR9 Activation. PLoS ONE. 2015;10:e0135898 pubmed publisher
Vogel A, Brown D. Single-Dose CpG Immunization Protects Against a Heterosubtypic Challenge and Generates Antigen-Specific Memory T Cells. Front Immunol. 2015;6:327 pubmed publisher
Dey M, Chang A, Miska J, Wainwright D, Ahmed A, Balyasnikova I, et al. Dendritic Cell-Based Vaccines that Utilize Myeloid Rather than Plasmacytoid Cells Offer a Superior Survival Advantage in Malignant Glioma. J Immunol. 2015;195:367-76 pubmed publisher
Huang H, Chen H, Evankovich J, Yan W, Rosborough B, Nace G, et al. Histones activate the NLRP3 inflammasome in Kupffer cells during sterile inflammatory liver injury. J Immunol. 2013;191:2665-79 pubmed publisher
Fu Y, Ding Y, Zhou T, Fu X, Xu W. Plasmodium yoelii blood-stage primes macrophage-mediated innate immune response through modulation of toll-like receptor signalling. Malar J. 2012;11:104 pubmed publisher
Kurotaki D, Kon S, Bae K, Ito K, Matsui Y, Nakayama Y, et al. CSF-1-dependent red pulp macrophages regulate CD4 T cell responses. J Immunol. 2011;186:2229-37 pubmed publisher
Fukata M, Breglio K, Chen A, Vamadevan A, Goo T, Hsu D, et al. The myeloid differentiation factor 88 (MyD88) is required for CD4+ T cell effector function in a murine model of inflammatory bowel disease. J Immunol. 2008;180:1886-94 pubmed

product information

Product Type :

Antibody

Product Name :

CD289 (TLR9) Monoclonal Antibody (M9.D6), eBioscience

Catalog # :

14-9093-95

Quantity :

10 mg

Price :

US 3685.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 1 ug/test, Western Blot: Assay-Dependent

Species :

Mouse

Clone :

M9.D6

Isotype :

IgG2a, kappa

Storage :

4 C

Description :

The protein encoded by this gene is a member of the Toll-like receptor family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1 ug/test, Western Blot: Assay-Dependent

Aliases :

CD289; Tlr9; toll like receptor 9; toll-like receptor 9; UNQ5798/PRO19605