CD257 (BAFF, BLyS) Monoclonal Antibody (1D6), eBioscience™ | Invitrogen 14-9017-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD257 (BAFF, BLyS) Monoclonal Antibody (1D6), eBioscience™

catalog :

14-9017-82

quantity :

100 µg

price :

256 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1D6

reactivity :

human

application :

western blot, immunohistochemistry, flow cytometry

more info or order :

Invitrogen product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; tbl 1	Magri G, Miyajima M, Bascones S, Mortha A, Puga I, Cassis L, et al. Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells. Nat Immunol. 2014;15:354-364 pubmed publisher
	Lowin T, Anssar T, Bäuml M, Classen T, Schneider M, Pongratz G. Positive and negative cooperativity of TNF and Interferon-γ in regulating synovial fibroblast function and B cell survival in fibroblast/B cell co-cultures. Sci Rep. 2020;10:780 pubmed publisher
	Imbrechts M, De Samblancx K, Fierens K, Brisse E, Vandenhaute J, Mitera T, et al. IFN-γ stimulates CpG-induced IL-10 production in B cells via p38 and JNK signalling pathways. Eur J Immunol. 2018;48:1506-1521 pubmed publisher
	Bornacelly A, Mercado D, Acevedo N, Caraballo L. The strength of the antibody response to the nematode Ascaris lumbricoides inversely correlates with levels of B-Cell Activating Factor (BAFF). BMC Immunol. 2014;15:22 pubmed publisher
	Hase H, Kanno Y, Kojima M, Hasegawa K, Sakurai D, Kojima H, et al. BAFF/BLyS can potentiate B-cell selection with the B-cell coreceptor complex. Blood. 2004;103:2257-65 pubmed
	Kayagaki N, Yan M, Seshasayee D, Wang H, Lee W, French D, et al. BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2. Immunity. 2002;17:515-24 pubmed
	Roschke V, Sosnovtseva S, Ward C, Hong J, Smith R, Albert V, et al. BLyS and APRIL form biologically active heterotrimers that are expressed in patients with systemic immune-based rheumatic diseases. J Immunol. 2002;169:4314-21 pubmed
	Hsu B, Harless S, Lindsley R, Hilbert D, Cancro M. Cutting edge: BLyS enables survival of transitional and mature B cells through distinct mediators. J Immunol. 2002;168:5993-6 pubmed
	Yan M, Brady J, Chan B, Lee W, Hsu B, Harless S, et al. Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency. Curr Biol. 2001;11:1547-52 pubmed

product information

Product Type :

Antibody

Product Name :

CD257 (BAFF, BLyS) Monoclonal Antibody (1D6), eBioscience™

Catalog # :

14-9017-82

Quantity :

100 µg

Price :

256 USD

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 1 µg/test, Immunohistochemistry: Assay-Dependent, Western Blot: Assay-Dependent

Species :

Human

Clone :

1D6

Isotype :

IgG1, kappa

Storage :

4° C

Description :

BAFF is a membrane bound cytokine expressed by B cell lineage cells. The soluble form of the cytokine binds to the receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. BAFF is a potent B cell activator, and important for the proliferation and differentiation of B cells. BAFF is also expressed by T lymphocytes and has been shown to promote T cell activation and survival. Isoforms representing alternatively spliced, and glycosylated variants have been identified.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1 µg/test, Immunohistochemistry: Assay-Dependent, Western Blot: Assay-Dependent

Aliases :

ApoL related ligand TALL-1; b cell-activating factor; B lymphocyte stimulator; BAFF; B-cell-activating factor; B-lymphocyte stimulator; BLyS; CD257; D8Ertd387e; delta BAFF; Delta4 BAFF; dendritic cell-derived TNF-like molecule; DTL; RGD1561519; TALL1; TALL-1; THANK; TNF- and APOL-related leukocyte expressed ligand 1; TNF and ApoL-related leukocyte expressed ligand 1; TNF homolog that activates apoptosis; Tnfsf13b; TNFSF20; TNLG7A; tumor necrosis factor (ligand) superfamily member 13b; tumor necrosis factor (ligand) superfamily, member 13b; tumor necrosis factor (ligand) superfamily, member 20; tumor necrosis factor ligand 7A; tumor necrosis factor ligand superfamily member 13B; Tumor necrosis factor ligand superfamily member 13b, membrane form; Tumor necrosis factor ligand superfamily member 13b, soluble form; tumor necrosis factor superfamily member 13b; tumor necrosis factor-like protein ZTNF4; UNQ401/PRO738; ZTNF4

more info or order :

Invitrogen product webpage