This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
SSEA4 Monoclonal Antibody (eBioMC-813-70 (MC-813-70)), eBioscience
catalog :
14-8843-80
quantity :
25 ug
price :
US 176.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
eBioMC-813-70 (MC-813-70)
application :
immunohistochemistry, immunocytochemistry, flow cytometry
citations: 25
Reference
Sesé B, Íñiguez Muñoz S, Ensenyat Mendez M, Llinàs Arias P, Ramis G, Orozco J, et al. Glioblastoma Embryonic-like Stem Cells Exhibit Immune-Evasive Phenotype. Cancers (Basel). 2022;14: pubmed publisher
Patananan A, Sercel A, Wu T, Ahsan F, Torres A, Kennedy S, et al. Pressure-Driven Mitochondrial Transfer Pipeline Generates Mammalian Cells of Desired Genetic Combinations and Fates. Cell Rep. 2020;33:108562 pubmed publisher
Xu X, Pradhan M, Xu M, Cheng Y, Beers J, Linask K, et al. Four induced pluripotent stem cell lines (TRNDi021-C, TRNDi023-D, TRNDi024-D and TRNDi025-A) generated from fibroblasts of four healthy individuals. Stem Cell Res. 2020;49:102011 pubmed publisher
Vukusic K, Sandstedt M, Jonsson M, Jansson M, Oldfors A, Jeppson A, et al. The atrioventricular junction - a potential niche region for progenitor cells in the adult human heart. Stem Cells Dev. 2019;: pubmed publisher
Hong J, Xu M, Li R, Cheng Y, Kouznetsova J, Beers J, et al. Generation of an induced pluripotent stem cell line (TRNDi008-A) from a Hunter syndrome patient carrying a hemizygous 208insC mutation in the IDS gene. Stem Cell Res. 2019;37:101451 pubmed publisher
Huang W, Xu M, Li R, Baskfield A, Kouznetsova J, Beers J, et al. An induced pluripotent stem cell line (TRNDi006-A) from a MPS IIIB patient carrying homozygous mutation of p.Glu153Lys in the NAGLU gene. Stem Cell Res. 2019;37:101427 pubmed publisher
Fujii S, Yoshida S, Inagaki E, Hatou S, Tsubota K, Takahashi M, et al. Immunological properties of neural crest cells derived from human induced pluripotent stem cells. Stem Cells Dev. 2018;: pubmed publisher
Alari V, Russo S, Rovina D, Gowran A, Garzo M, Crippa M, et al. Generation of the Rubinstein-Taybi syndrome type 2 patient-derived induced pluripotent stem cell line (IAIi001-A) carrying the EP300 exon 23 stop mutation c.3829A > T, p.(Lys1277*). Stem Cell Res. 2018;30:175-179 pubmed publisher
Kondrashov A, Duc Hoang M, Smith J, Bhagwan J, Duncan G, Mosqueira D, et al. Simplified Footprint-Free Cas9/CRISPR Editing of Cardiac-Associated Genes in Human Pluripotent Stem Cells. Stem Cells Dev. 2018;27:391-404 pubmed publisher
Säljö K, Barone A, Vizlin Hodzic D, Johansson B, Breimer M, Funa K, et al. Comparison of the glycosphingolipids of human-induced pluripotent stem cells and human embryonic stem cells. Glycobiology. 2017;27:291-305 pubmed publisher
Johansson M, Dedic B, Lundholm K, Branzell F, Barone A, Benktander J, et al. Characterization of moose intestinal glycosphingolipids. Glycoconj J. 2015;32:393-412 pubmed publisher
Barone A, Säljö K, Benktander J, Blomqvist M, Mansson J, Johansson B, et al. Sialyl-lactotetra, a novel cell surface marker of undifferentiated human pluripotent stem cells. J Biol Chem. 2014;289:18846-59 pubmed publisher
Kazemnejad S, Zarnani A, Khanmohammadi M, Mobini S. Chondrogenic differentiation of menstrual blood-derived stem cells on nanofibrous scaffolds. Methods Mol Biol. 2013;1058:149-69 pubmed publisher
Rosu Myles M, McCully J, Fair J, Mehic J, Menendez P, Rodriguez R, et al. The globoseries glycosphingolipid SSEA-4 is a marker of bone marrow-derived clonal multipotent stromal cells in vitro and in vivo. Stem Cells Dev. 2013;22:1387-97 pubmed publisher
Vickers D, Kulik M, Hincapie M, Hancock W, Dalton S, Murthy S. Lectin-functionalized microchannels for characterizing pluripotent cells and early differentiation. Biomicrofluidics. 2012;6:24122-2412210 pubmed publisher
Cheng C, Lian W, Hsiao F, Liu I, Lin S, Lee Y, et al. Isolation and characterization of novel murine epiphysis derived mesenchymal stem cells. PLoS ONE. 2012;7:e36085 pubmed publisher
Silk K, Leishman A, Nishimoto K, Reddy A, Fairchild P. Rapamycin conditioning of dendritic cells differentiated from human ES cells promotes a tolerogenic phenotype. J Biomed Biotechnol. 2012;2012:172420 pubmed publisher
Marlicz W, Zuba Surma E, Kucia M, Blogowski W, Starzynska T, Ratajczak M. Various types of stem cells, including a population of very small embryonic-like stem cells, are mobilized into peripheral blood in patients with Crohn's disease. Inflamm Bowel Dis. 2012;18:1711-22 pubmed publisher
Prabakar K, Dominguez Bendala J, Molano R, Pileggi A, Villate S, Ricordi C, et al. Generation of glucose-responsive, insulin-producing cells from human umbilical cord blood-derived mesenchymal stem cells. Cell Transplant. 2012;21:1321-39 pubmed publisher
Williams S, Stanley P. Complex N-glycans or core 1-derived O-glycans are not required for the expression of stage-specific antigens SSEA-1, SSEA-3, SSEA-4, or Le(Y) in the preimplantation mouse embryo. Glycoconj J. 2009;26:335-47 pubmed publisher
Muller T, Eildermann K, Dhir R, Schlatt S, Behr R. Glycan stem-cell markers are specifically expressed by spermatogonia in the adult non-human primate testis. Hum Reprod. 2008;23:2292-8 pubmed publisher
Shiue Y, Tailiu J, Liou J, Lu H, Tai C, Shiau J, et al. Establishment of the long-term in vitro culture system for chicken primordial germ cells. Reprod Domest Anim. 2009;44:55-61 pubmed publisher
Gang E, Bosnakovski D, Figueiredo C, Visser J, Perlingeiro R. SSEA-4 identifies mesenchymal stem cells from bone marrow. Blood. 2007;109:1743-51 pubmed
Krupnick J, Damjanov I, Damjanov A, Zhu Z, Fenderson B. Globo-series carbohydrate antigens are expressed in different forms on human and murine teratocarcinoma-derived cells. Int J Cancer. 1994;59:692-8 pubmed
Kannagi R, Cochran N, Ishigami F, Hakomori S, Andrews P, Knowles B, et al. Stage-specific embryonic antigens (SSEA-3 and -4) are epitopes of a unique globo-series ganglioside isolated from human teratocarcinoma cells. EMBO J. 1983;2:2355-61 pubmed
product information
Product Type :
Antibody
Product Name :
SSEA4 Monoclonal Antibody (eBioMC-813-70 (MC-813-70)), eBioscience
Catalog # :
14-8843-80
Quantity :
25 ug
Price :
US 176.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Canine, Chicken, Human, Mouse, Non-human primate, Rabbit
Applications :
Flow Cytometry: 1 ug/test, Immunocytochemistry: Assay-Dependent, Immunohistochemistry: Assay-Dependent
Species :
Canine, Chicken, Human, Mouse, Non-human primate, Rabbit
Clone :
eBioMC-813-70 (MC-813-70)
Isotype :
IgG3
Storage :
4 C
Description :
SSEA-4 (Stage-specific embryonic antigen 4) is a cell surface antigen, expressed along with SSEA-3, TRA-1-60 and TRA-1-81 in embryonic stem cells, embryonal carcinoma cells and induced pluripotent stem cells (iPS). In human cells, these surface markers are down-regulated during the differentiation process, while SSEA-1 is absent in undifferentiated human stem cells and upregulated on the cell surface after retinoic acid mediated differentiation. Conversely, in mouse stem cells, SSEA-1 expression decreases with differentiation while SSEA-3 and SSEA-4 expression increase.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1 ug/test, Immunocytochemistry: Assay-Dependent, Immunohistochemistry: Assay-Dependent
Aliases :
SSEA-4; stage-specific embryonic antigen 4
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA