CX3CL1 (Fractalkine) Polyclonal Antibody, eBioscience | Invitrogen 14-7986-81 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CX3CL1 (Fractalkine) Polyclonal Antibody, eBioscience

catalog :

14-7986-81

quantity :

50 ug

price :

US 124.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - frozen section

citations: 4

Reference
Gomyo Furuya N, Kamio N, Watanabe T, Hayama T, Fukai J, Kuramochi K, et al. Fractalkine's dual role in inflammation and hard tissue formation in cultured human dental pulp cells. Biomed Res. 2023;44:257-264 pubmed publisher
Yan H, Wu J, Yan H. iRHOM2 regulates inflammation and endothelial barrier permeability via CX3CL1. Exp Ther Med. 2023;26:319 pubmed publisher
Zhang M, Liu H, Huang K, Peng Y, Tao Y, Zhao C, et al. Fuzheng Huayu Recipe Prevented and Treated CCl4-Induced Mice Liver Fibrosis through Regulating Polarization and Chemotaxis of Intrahepatic Macrophages via CCL2 and CX3CL1. Evid Based Complement Alternat Med. 2020;2020:8591892 pubmed publisher
O Sullivan S, Gasparini F, Mir A, Dev K. Fractalkine shedding is mediated by p38 and the ADAM10 protease under pro-inflammatory conditions in human astrocytes. J Neuroinflammation. 2016;13:189 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CX3CL1 (Fractalkine) Polyclonal Antibody, eBioscience

Catalog # :

14-7986-81

Quantity :

50 ug

Price :

US 124.00

Clonality :

Polyclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunohistochemistry (Frozen): 1:100-1:500, Immunoprecipitation: 1:300-1:800, Western Blot: 1:1,000-1:5,000

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

4 C

Description :

Chemokines are a family of proteins associated with the trafficking of leukocytes in immune surveillance and inflammatory cell recruitment. They are classified based on the positions of key cysteine residues. CX3CL1 is a CX3C chemokine known to induce adhesion and migration of leukocytes mediated by a membrane-bound and soluble form respectively. Recent experiments have shown that CX3CL1 can suppress the production of nitrous oxide, interleukin-6, and TNF-a in activated microglia and neuronal cells, suggesting that it may act as an intrinsic inhibitor against neurotoxicity by activated microglia. Its receptor, CX3CR1, also functions as a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by CX3CL1.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Frozen): 1:100-1:500, Immunoprecipitation: 1:300-1:800, Western Blot: 1:1,000-1:5,000

Aliases :

A-152E5.2; AB030188; ABCD-3; Acc1; AI848747; C3Xkine; chemokine (C-X3-C motif) ligand 1; CX3C; CX3C membrane-anchored chemokine; C-X3-C motif chemokine 1; C-X3-C motif chemokine ligand 1; Cx3cl1; CXC3; CXC3C; D8Bwg0439e; Fkn; Fractalkine; neurotactin; NTN; NTT; Processed fractalkine; SCYD1; small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin); small inducible cytokine subfamily D (Cys-X3-Cys), member-1; small inducible cytokine subfamily D, 1; small-inducible cytokine D1