| Published Application/Species/Sample/Dilution | Reference |
|---|
- flow cytometry; mouse; loading ...; fig 1f
| Lewis G, Wehrens E, Labarta Bajo L, Streeck H, Zuniga E. TGF-? receptor maintains CD4 T helper cell identity during chronic viral infections. J Clin Invest. 2016;126:3799-3813 pubmed publisher |
- flow cytometry; human; loading ...; fig 6d
| Nakhlé J, Pierron V, Bauchet A, Plas P, Thiongane A, Meyer Losic F, et al. Tasquinimod modulates tumor-infiltrating myeloid cells and improves the antitumor immune response to PD-L1 blockade in bladder cancer. Oncoimmunology. 2016;5:e1145333 pubmed publisher |
- flow cytometry; mouse; fig 5
| Kim J, Phan T, Nguyen V, Dinh Vu H, Zheng J, Yun M, et al. Salmonella typhimurium Suppresses Tumor Growth via the Pro-Inflammatory Cytokine Interleukin-1β. Theranostics. 2015;5:1328-42 pubmed publisher |
- flow cytometry; mouse; loading ...; fig 2a
| Kurtulus S, Sakuishi K, Ngiow S, Joller N, Tan D, Teng M, et al. TIGIT predominantly regulates the immune response via regulatory T cells. J Clin Invest. 2015;125:4053-62 pubmed publisher |
- flow cytometry; mouse; fig 5
| Pannu J, Belle J, Forster M, Duerr C, Shen S, Kane L, et al. Ubiquitin specific protease 21 is dispensable for normal development, hematopoiesis and lymphocyte differentiation. PLoS ONE. 2015;10:e0117304 pubmed publisher |
- flow cytometry; mouse; fig 2
| Zhang Y, Wu B, Metelli A, Thaxton J, Hong F, Rachidi S, et al. GP96 is a GARP chaperone and controls regulatory T cell functions. J Clin Invest. 2015;125:859-69 pubmed publisher |
- flow cytometry; mouse; fig 5
| Cabrera Perez J, Condotta S, James B, Kashem S, Brincks E, Rai D, et al. Alterations in antigen-specific naive CD4 T cell precursors after sepsis impairs their responsiveness to pathogen challenge. J Immunol. 2015;194:1609-20 pubmed publisher |
- flow cytometry; human; fig 3
| Hannani D, Vétizou M, Enot D, Rusakiewicz S, Chaput N, Klatzmann D, et al. Anticancer immunotherapy by CTLA-4 blockade: obligatory contribution of IL-2 receptors and negative prognostic impact of soluble CD25. Cell Res. 2015;25:208-24 pubmed publisher |
- flow cytometry; mouse; fig 2
| Sullivan B, Teijaro J, de la Torre J, Oldstone M. Early virus-host interactions dictate the course of a persistent infection. PLoS Pathog. 2015;11:e1004588 pubmed publisher |
- flow cytometry; mouse
- immunocytochemistry; mouse
| Hu Z, Molloy M, Usherwood E. CD4(+) T-cell dependence of primary CD8(+) T-cell response against vaccinia virus depends upon route of infection and viral dose. Cell Mol Immunol. 2016;13:82-93 pubmed publisher |
| Yuan X, Dee M, Altman N, Malek T. IL-2Rβ-dependent signaling and CD103 functionally cooperate to maintain tolerance in the gut mucosa. J Immunol. 2015;194:1334-46 pubmed publisher |
- flow cytometry; mouse; fig 1
| Mehta P, Nuotio Antar A, Smith C. γδ T cells promote inflammation and insulin resistance during high fat diet-induced obesity in mice. J Leukoc Biol. 2015;97:121-34 pubmed publisher |
| Wang X, Sumida H, Cyster J. GPR18 is required for a normal CD8αα intestinal intraepithelial lymphocyte compartment. J Exp Med. 2014;211:2351-9 pubmed publisher |
- flow cytometry; mouse; fig 3f
| Backer R, Helbig C, Gentek R, Kent A, Laidlaw B, Dominguez C, et al. A central role for Notch in effector CD8(+) T cell differentiation. Nat Immunol. 2014;15:1143-51 pubmed publisher |
- flow cytometry; mouse; loading ...; fig 4c
| Dai M, Yip Y, Hellstrom I, Hellstrom K. Curing mice with large tumors by locally delivering combinations of immunomodulatory antibodies. Clin Cancer Res. 2015;21:1127-38 pubmed publisher |
- flow cytometry; mouse; fig 4
| Yan J, Villarreal D, Racine T, Chu J, Walters J, Morrow M, et al. Protective immunity to H7N9 influenza viruses elicited by synthetic DNA vaccine. Vaccine. 2014;32:2833-42 pubmed publisher |
| Joedicke J, Dietze K, Zelinskyy G, Dittmer U. The phenotype and activation status of regulatory T cells during Friend retrovirus infection. Virol Sin. 2014;29:48-60 pubmed publisher |
| Chatterjee S, Eby J, Al Khami A, Soloshchenko M, Kang H, Kaur N, et al. A quantitative increase in regulatory T cells controls development of vitiligo. J Invest Dermatol. 2014;134:1285-1294 pubmed publisher |
- flow cytometry; mouse; fig s2
| Lu M, Varley A, Munford R. Persistently active microbial molecules prolong innate immune tolerance in vivo. PLoS Pathog. 2013;9:e1003339 pubmed publisher |
| Powell N, Walker A, Stolarczyk E, Canavan J, Gökmen M, Marks E, et al. The transcription factor T-bet regulates intestinal inflammation mediated by interleukin-7 receptor+ innate lymphoid cells. Immunity. 2012;37:674-84 pubmed publisher |
- flow cytometry; mouse; fig 5c
| Szretter K, Daniels B, Cho H, Gainey M, Yokoyama W, Gale M, et al. 2'-O methylation of the viral mRNA cap by West Nile virus evades ifit1-dependent and -independent mechanisms of host restriction in vivo. PLoS Pathog. 2012;8:e1002698 pubmed publisher |
| Pinto A, Daffis S, Brien J, Gainey M, Yokoyama W, Sheehan K, et al. A temporal role of type I interferon signaling in CD8+ T cell maturation during acute West Nile virus infection. PLoS Pathog. 2011;7:e1002407 pubmed publisher |
- flow cytometry; mouse; fig 6, 7
| Gibbert K, Dietze K, Zelinskyy G, Lang K, Barchet W, Kirschning C, et al. Polyinosinic-polycytidylic acid treatment of Friend retrovirus-infected mice improves functional properties of virus-specific T cells and prevents virus-induced disease. J Immunol. 2010;185:6179-89 pubmed publisher |
- flow cytometry; mouse; fig 1
| Garidou L, Heydari S, Truong P, Brooks D, McGavern D. Therapeutic memory T cells require costimulation for effective clearance of a persistent viral infection. J Virol. 2009;83:8905-15 pubmed publisher |
| Sprengers D, Sillé F, Derkow K, Besra G, Janssen H, Schott E, et al. Critical role for CD1d-restricted invariant NKT cells in stimulating intrahepatic CD8 T-cell responses to liver antigen. Gastroenterology. 2008;134:2132-43 pubmed publisher |
| Sridhar S, Reyes Sandoval A, Draper S, Moore A, Gilbert S, Gao G, et al. Single-dose protection against Plasmodium berghei by a simian adenovirus vector using a human cytomegalovirus promoter containing intron A. J Virol. 2008;82:3822-33 pubmed publisher |
- flow cytometry; mouse; fig 2
| Badovinac V, Harty J. Manipulating the rate of memory CD8+ T cell generation after acute infection. J Immunol. 2007;179:53-63 pubmed |
- flow cytometry; mouse; fig 4A
| Nakae S, Iwakura Y, Suto H, Galli S. Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17. J Leukoc Biol. 2007;81:1258-68 pubmed |
| Yang G, Wang J, Wang S, Zhu Y. Forsythiaside A Improves the Inhibitory Efficiency of Recombinant Protein Vaccines against Bovine Viral Diarrhea Virus Infection. Int J Mol Sci. 2022;23: pubmed publisher |
| Xie F, Zhou X, Su P, Li H, Tu Y, Du J, et al. Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling. Nat Commun. 2022;13:4461 pubmed publisher |
| Luo Y, Guo J, Jia W, Wu M, Yin F, Niu G, et al. TNF-Like Ligand 1 Aberrance Aggravates Nonalcoholic Steatohepatitis via M1 Macrophage Polarization. Oxid Med Cell Longev. 2021;2021:3877617 pubmed publisher |
| Mould R, van Vloten J, AuYeung A, Walsh S, de Jong J, Susta L, et al. Using a Prime-Boost Vaccination Strategy That Proved Effective for High Resolution Epitope Mapping to Characterize the Elusive Immunogenicity of Survivin. Cancers (Basel). 2021;13: pubmed publisher |
| Yu H, Yang W, Huang J, Miao X, Wang B, Ren X, et al. GPR120 induces regulatory dendritic cells by inhibiting HK2-dependent glycolysis to alleviate fulminant hepatic failure. Cell Death Dis. 2021;13:1 pubmed publisher |
| Medina Buelvas D, Rodr xed guez Sosa M, Vega L. Characterisation of Macrophage Polarisation in Mice Infected with Ninoa Strain of Trypanosoma cruzi. Pathogens. 2021;10: pubmed publisher |
| Chun N, ANG R, Chan M, Fairchild R, Baldwin W, Horwitz J, et al. T cell-derived tumor necrosis factor induces cytotoxicity by activating RIPK1-dependent target cell death. JCI Insight. 2021;6: pubmed publisher |
| Liu J, Liu Y, Panda S, Liu A, Lei J, Burd I. Type 1 Cytotoxic T Cells Increase in Placenta after Intrauterine Inflammation. Front Immunol. 2021;12:718563 pubmed publisher |
| Conforti A, Marra E, Palombo F, Roscilli G, Ravà M, Fumagalli V, et al. COVID-eVax, an electroporated DNA vaccine candidate encoding the SARS-CoV-2 RBD, elicits protective responses in animal models. Mol Ther. 2021;: pubmed publisher |
| Yang Z, Xu G, Wang B, Liu Y, Zhang L, Jing T, et al. USP12 downregulation orchestrates a protumourigenic microenvironment and enhances lung tumour resistance to PD-1 blockade. Nat Commun. 2021;12:4852 pubmed publisher |
| AuYeung A, Mould R, Stegelmeier A, van Vloten J, Karimi K, Woods J, et al. Mechanisms that allow vaccination against an oncolytic vesicular stomatitis virus-encoded transgene to enhance safety without abrogating oncolysis. Sci Rep. 2021;11:15290 pubmed publisher |
| Pu J, Xu Z, Nian J, Fang Q, Yang M, Huang Y, et al. M2 macrophage-derived extracellular vesicles facilitate CD8+T cell exhaustion in hepatocellular carcinoma via the miR-21-5p/YOD1/YAP/β-catenin pathway. Cell Death Discov. 2021;7:182 pubmed publisher |
| Liu L, Wu Y, Wang B, Jiang Y, Lin L, Li X, et al. DA-DRD5 signaling controls colitis by regulating colonic M1/M2 macrophage polarization. Cell Death Dis. 2021;12:500 pubmed publisher |
| Zhou J, Kryczek I, Li S, Li X, Aguilar A, Wei S, et al. The ubiquitin ligase MDM2 sustains STAT5 stability to control T cell-mediated antitumor immunity. Nat Immunol. 2021;22:460-470 pubmed publisher |
| Srivastava S, Furlan S, Jaeger Ruckstuhl C, Sarvothama M, Berger C, Smythe K, et al. Immunogenic Chemotherapy Enhances Recruitment of CAR-T Cells to Lung Tumors and Improves Antitumor Efficacy when Combined with Checkpoint Blockade. Cancer Cell. 2021;39:193-208.e10 pubmed publisher |
| Zheng J, Wong L, Li K, Verma A, Ortiz M, Wohlford Lenane C, et al. COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice. Nature. 2021;589:603-607 pubmed publisher |
| Zhao K, Tian Y, Wang J, Chen C, Pan B, Yan Z, et al. Fluvastatin-Pretreated Donor Cells Attenuated Murine aGVHD by Balancing Effector T Cell Distribution and Function under the Regulation of KLF2. Biomed Res Int. 2020;2020:7619849 pubmed publisher |
| Brar G, Farhat N, Sukhina A, Lam A, Kim Y, Hsu T, et al. Deletion of immune evasion genes provides an effective vaccine design for tumor-associated herpesviruses. NPJ Vaccines. 2020;5:102 pubmed publisher |
| Huang T, Fu G, Gao J, Zhang Y, Cai W, Wu S, et al. Fgr contributes to hemorrhage-induced thalamic pain by activating NF-κB/ERK1/2 pathways. JCI Insight. 2020;5: pubmed publisher |
| Lee S, Kim S, Kang H, Lim H, Kwon Y, Jo M, et al. The overexpression of TDP-43 in astrocytes causes neurodegeneration via a PTP1B-mediated inflammatory response. J Neuroinflammation. 2020;17:299 pubmed publisher |
| Ghergurovich J, García Cañaveras J, Wang J, Schmidt E, Zhang Z, Teslaa T, et al. A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway. Nat Chem Biol. 2020;16:731-739 pubmed publisher |
| Jaeger Ruckstuhl C, Hinterbrandner M, H xf6 pner S, Correnti C, L xfc thi U, Friedli O, et al. TNIK signaling imprints CD8+ T cell memory formation early after priming. Nat Commun. 2020;11:1632 pubmed publisher |
| Kim K, Lee J, Ahn S, Won R, Kim S, Jeong S, et al. The methanol extract of Guettarda speciosa Linn. Ameliorates acute lung injury in mice. BMC Complement Med Ther. 2020;20:40 pubmed publisher |
| Reeder S, Reuschel E, Bah M, Yun K, Tursi N, Kim K, et al. Synthetic DNA Vaccines Adjuvanted with pIL-33 Drive Liver-Localized T Cells and Provide Protection from Plasmodium Challenge in a Mouse Model. Vaccines (Basel). 2020;8: pubmed publisher |
| Tian D, Hong H, Shang W, Ho C, Dong J, Tian X. Deletion of Ppard in CD11c+ cells attenuates atherosclerosis in ApoE knockout mice. FASEB J. 2020;34:3367-3378 pubmed publisher |
| Cai D, Li J, Liu D, Hong S, Qiao Q, Sun Q, et al. Tumor-expressed B7-H3 mediates the inhibition of antitumor T-cell functions in ovarian cancer insensitive to PD-1 blockade therapy. Cell Mol Immunol. 2019;: pubmed publisher |
| Xu J, Pei S, Wang Y, Liu J, Qian Y, Huang M, et al. Tpl2 Protects Against Fulminant Hepatitis Through Mobilization of Myeloid-Derived Suppressor Cells. Front Immunol. 2019;10:1980 pubmed publisher |
| Herrmann O, Kuepper M, Bütow M, Costa I, Appelmann I, Beier F, et al. Infliximab therapy together with tyrosine kinase inhibition targets leukemic stem cells in chronic myeloid leukemia. BMC Cancer. 2019;19:658 pubmed publisher |
| Ou P, Wen L, Liu X, HUANG J, Huang X, Su C, et al. Thioesterase PPT1 balances viral resistance and efficient T cell crosspriming in dendritic cells. J Exp Med. 2019;: pubmed publisher |
| Zhou X, Yu J, Cheng X, Zhao B, Manyam G, Zhang L, et al. The deubiquitinase Otub1 controls the activation of CD8+ T cells and NK cells by regulating IL-15-mediated priming. Nat Immunol. 2019;20:879-889 pubmed publisher |
| Mielke L, Liao Y, Clemens E, Firth M, Duckworth B, Huang Q, et al. TCF-1 limits the formation of Tc17 cells via repression of the MAF-RORγt axis. J Exp Med. 2019;: pubmed publisher |
| Wang W, Green M, Choi J, Gijon M, Kennedy P, Johnson J, et al. CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy. Nature. 2019;569:270-274 pubmed publisher |
| Sun R, Hedl M, Abraham C. Twist1 and Twist2 Induce Human Macrophage Memory upon Chronic Innate Receptor Treatment by HDAC-Mediated Deacetylation of Cytokine Promoters. J Immunol. 2019;202:3297-3308 pubmed publisher |
| Zhou L, Chu C, Teng F, Bessman N, Goc J, Santosa E, et al. Innate lymphoid cells support regulatory T cells in the intestine through interleukin-2. Nature. 2019;568:405-409 pubmed publisher |
| Cao Y, Trillo Tinoco J, Sierra R, Anadon C, Dai W, Mohamed E, et al. ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression. Nat Commun. 2019;10:1280 pubmed publisher |
| Cullen J, McQuilten H, Quinn K, Olshansky M, Russ B, Morey A, et al. CD4+ T help promotes influenza virus-specific CD8+ T cell memory by limiting metabolic dysfunction. Proc Natl Acad Sci U S A. 2019;: pubmed publisher |
| Cheng W, Tsui Y, Ragusa S, Koelzer V, Mina M, Franco F, et al. Uncoupling protein 2 reprograms the tumor microenvironment to support the anti-tumor immune cycle. Nat Immunol. 2019;20:206-217 pubmed publisher |
| Miyakoda M, Bayarsaikhan G, Kimura D, Akbari M, Udono H, Yui K. Metformin Promotes the Protection of Mice Infected With Plasmodium yoelii Independently of γδ T Cell Expansion. Front Immunol. 2018;9:2942 pubmed publisher |
| Amir M, Chaudhari S, Wang R, Campbell S, Mosure S, Chopp L, et al. REV-ERBα Regulates TH17 Cell Development and Autoimmunity. Cell Rep. 2018;25:3733-3749.e8 pubmed publisher |
| Gross D, Ghenassia A, Bartolo L, Urbain D, Benkhelifa Ziyyat S, Lorain S, et al. Cross-Presentation of Skin-Targeted Recombinant Adeno-associated Virus 2/1 Transgene Induces Potent Resident Memory CD8+ T Cell Responses. J Virol. 2019;93: pubmed publisher |
| Ekiz H, Lai S, Gundlapalli H, Haroun F, Williams M, Welm A. Inhibition of RON kinase potentiates anti-CTLA-4 immunotherapy to shrink breast tumors and prevent metastatic outgrowth. Oncoimmunology. 2018;7:e1480286 pubmed publisher |
| Hung A, Maxwell R, Theodros D, Belcaid Z, Mathios D, Luksik A, et al. TIGIT and PD-1 dual checkpoint blockade enhances antitumor immunity and survival in GBM. Oncoimmunology. 2018;7:e1466769 pubmed publisher |
| Wasnik S, Rundle C, Baylink D, Yazdi M, Carreon E, Xu Y, et al. 1,25-Dihydroxyvitamin D suppresses M1 macrophages and promotes M2 differentiation at bone injury sites. JCI Insight. 2018;3: pubmed publisher |
| Tilstra J, Avery L, Menk A, Gordon R, Smita S, Kane L, et al. Kidney-infiltrating T cells in murine lupus nephritis are metabolically and functionally exhausted. J Clin Invest. 2018;128:4884-4897 pubmed publisher |
| Tejero J, Armand N, Finn C, Dhume K, Strutt T, Chai K, et al. Cigarette smoke extract acts directly on CD4 T cells to enhance Th1 polarization and reduce memory potential. Cell Immunol. 2018;331:121-129 pubmed publisher |
| Privratsky J, Zhang J, Lu X, Rudemiller N, Wei Q, Yu Y, et al. Interleukin 1 receptor (IL-1R1) activation exacerbates toxin-induced acute kidney injury. Am J Physiol Renal Physiol. 2018;315:F682-F691 pubmed publisher |
| Seydoux E, Liang H, Dubois Cauwelaert N, Archer M, Rintala N, Kramer R, et al. Effective Combination Adjuvants Engage Both TLR and Inflammasome Pathways To Promote Potent Adaptive Immune Responses. J Immunol. 2018;201:98-112 pubmed publisher |
| Ritzel R, Lai Y, Crapser J, Patel A, Schrecengost A, Grenier J, et al. Aging alters the immunological response to ischemic stroke. Acta Neuropathol. 2018;136:89-110 pubmed publisher |
| Elsayed H, Nabi G, McKinstry W, Khoo K, Mak J, Salazar A, et al. Intrastructural Help: Harnessing T Helper Cells Induced by Licensed Vaccines for Improvement of HIV Env Antibody Responses to Virus-Like Particle Vaccines. J Virol. 2018;92: pubmed publisher |
| Theisen E, McDougal C, Nakanishi M, Stevenson D, Amador Noguez D, Rosenberg D, et al. Cyclooxygenase-1 and -2 Play Contrasting Roles in Listeria-Stimulated Immunity. J Immunol. 2018;200:3729-3738 pubmed publisher |
| Lee S, Shi X, Fan A, West B, Zhang J. Targeting macrophage and microglia activation with colony stimulating factor 1 receptor inhibitor is an effective strategy to treat injury-triggered neuropathic pain. Mol Pain. 2018;14:1744806918764979 pubmed publisher |
| Xi J, Huang Q, Wang L, Ma X, Deng Q, Kumar M, et al. miR-21 depletion in macrophages promotes tumoricidal polarization and enhances PD-1 immunotherapy. Oncogene. 2018;37:3151-3165 pubmed publisher |
| Li C, Wang Y, Li Y, Yu Q, Jin X, Wang X, et al. HIF1α-dependent glycolysis promotes macrophage functional activities in protecting against bacterial and fungal infection. Sci Rep. 2018;8:3603 pubmed publisher |
| Hailemichael Y, Woods A, Fu T, He Q, Nielsen M, Hasan F, et al. Cancer vaccine formulation dictates synergy with CTLA-4 and PD-L1 checkpoint blockade therapy. J Clin Invest. 2018;128:1338-1354 pubmed publisher |
| Rodriguez Cetina Biefer H, Heinbokel T, Uehara H, Camacho V, Minami K, Nian Y, et al. Mast cells regulate CD4+ T-cell differentiation in the absence of antigen presentation. J Allergy Clin Immunol. 2018;142:1894-1908.e7 pubmed publisher |
| Yu J, Duong V, Westphal K, Westphal A, Suwandi A, Grassl G, et al. Surface receptor Toso controls B cell-mediated regulation of T cell immunity. J Clin Invest. 2018;128:1820-1836 pubmed publisher |
| Beesetty P, Wieczerzak K, Gibson J, Kaitsuka T, Luu C, Matsushita M, et al. Inactivation of TRPM7 kinase in mice results in enlarged spleens, reduced T-cell proliferation and diminished store-operated calcium entry. Sci Rep. 2018;8:3023 pubmed publisher |
| Bryan M, Giordano D, Draves K, Green R, Gale M, Clark E. Splenic macrophages are required for protective innate immunity against West Nile virus. PLoS ONE. 2018;13:e0191690 pubmed publisher |
| Kim D, Park H, Lim S, Koo J, Lee H, Choi J, et al. Regulation of chitinase-3-like-1 in T cell elicits Th1 and cytotoxic responses to inhibit lung metastasis. Nat Commun. 2018;9:503 pubmed publisher |
| Meier L, Auger J, Engelson B, Cowan H, Breed E, Gonzalez Torres M, et al. CD301b/MGL2+ Mononuclear Phagocytes Orchestrate Autoimmune Cardiac Valve Inflammation and Fibrosis. Circulation. 2018;137:2478-2493 pubmed publisher |
| Kang E, Zhou G, Yousefi M, Cayrol R, Xia J, Gruenheid S. Loss of disease tolerance during Citrobacter rodentium infection is associated with impaired epithelial differentiation and hyperactivation of T cell responses. Sci Rep. 2018;8:847 pubmed publisher |
| Field C, Hunn M, Ferguson P, Ruedl C, Ancelet L, Hermans I. Blocking CTLA-4 while priming with a whole cell vaccine reshapes the oligoclonal T cell infiltrate and eradicates tumors in an orthotopic glioma model. Oncoimmunology. 2017;7:e1376154 pubmed publisher |
| Delpoux A, Michelini R, Verma S, Lai C, Omilusik K, Utzschneider D, et al. Continuous activity of Foxo1 is required to prevent anergy and maintain the memory state of CD8+ T cells. J Exp Med. 2018;215:575-594 pubmed publisher |
| Sutavani R, Phair I, Barker R, McFarlane A, Shpiro N, Lang S, et al. Differential control of Toll-like receptor 4-induced interleukin-10 induction in macrophages and B cells reveals a role for p90 ribosomal S6 kinases. J Biol Chem. 2018;293:2302-2317 pubmed publisher |
| Milner J, Toma C, Yu B, Zhang K, Omilusik K, Phan A, et al. Runx3 programs CD8+ T cell residency in non-lymphoid tissues and tumours. Nature. 2017;552:253-257 pubmed publisher |
| Wang L, Zhu C, Zhang T, Tian Q, Zhang N, Morrison S, et al. Nonpathogenic Colonization with Chlamydia in the Gastrointestinal Tract as Oral Vaccination for Inducing Transmucosal Protection. Infect Immun. 2018;86: pubmed publisher |
| Ishihara J, Fukunaga K, Ishihara A, Larsson H, Potin L, Hosseinchi P, et al. Matrix-binding checkpoint immunotherapies enhance antitumor efficacy and reduce adverse events. Sci Transl Med. 2017;9: pubmed publisher |
| Wang Q, Ning H, Peng H, Wei L, Hou R, Hoft D, et al. Tristetraprolin inhibits macrophage IL-27-induced activation of antitumour cytotoxic T cell responses. Nat Commun. 2017;8:867 pubmed publisher |
| Pyle C, Uwadiae F, Swieboda D, Harker J. Early IL-6 signalling promotes IL-27 dependent maturation of regulatory T cells in the lungs and resolution of viral immunopathology. PLoS Pathog. 2017;13:e1006640 pubmed publisher |
| Ono Y, Pérez Gutiérrez A, Nakao T, Dai H, Camirand G, Yoshida O, et al. Graft-infiltrating PD-L1hi cross-dressed dendritic cells regulate antidonor T cell responses in mouse liver transplant tolerance. Hepatology. 2018;67:1499-1515 pubmed publisher |
| Danahy D, Anthony S, Jensen I, Hartwig S, Shan Q, Xue H, et al. Polymicrobial sepsis impairs bystander recruitment of effector cells to infected skin despite optimal sensing and alarming function of skin resident memory CD8 T cells. PLoS Pathog. 2017;13:e1006569 pubmed publisher |
| Thwe P, Pelgrom L, Cooper R, Beauchamp S, Reisz J, D Alessandro A, et al. Cell-Intrinsic Glycogen Metabolism Supports Early Glycolytic Reprogramming Required for Dendritic Cell Immune Responses. Cell Metab. 2017;26:558-567.e5 pubmed publisher |
| Peterson L, Philip N, DeLaney A, Wynosky Dolfi M, Asklof K, Gray F, et al. RIPK1-dependent apoptosis bypasses pathogen blockade of innate signaling to promote immune defense. J Exp Med. 2017;214:3171-3182 pubmed publisher |
| Taylor N, Vick S, Iglesia M, Brickey W, Midkiff B, McKinnon K, et al. Treg depletion potentiates checkpoint inhibition in claudin-low breast cancer. J Clin Invest. 2017;127:3472-3483 pubmed publisher |
| Li L, Labuda J, Imai D, Griffey S, McSorley S. CCR7 Deficiency Allows Accelerated Clearance of Chlamydia from the Female Reproductive Tract. J Immunol. 2017;199:2547-2554 pubmed publisher |
| Tischner D, Grimm M, Kaur H, Staudenraus D, Carvalho J, Looso M, et al. Single-cell profiling reveals GPCR heterogeneity and functional patterning during neuroinflammation. JCI Insight. 2017;2: pubmed publisher |
| Gullicksrud J, Li F, Xing S, Zeng Z, Peng W, Badovinac V, et al. Differential Requirements for Tcf1 Long Isoforms in CD8+ and CD4+ T Cell Responses to Acute Viral Infection. J Immunol. 2017;199:911-919 pubmed publisher |
| Ritzel R, Patel A, Spychala M, Verma R, Crapser J, Koellhoffer E, et al. Multiparity improves outcomes after cerebral ischemia in female mice despite features of increased metabovascular risk. Proc Natl Acad Sci U S A. 2017;114:E5673-E5682 pubmed publisher |
| Trsan T, Vuković K, Filipović P, Brizić A, Lemmermann N, Schober K, et al. Cytomegalovirus vector expressing RAE-1? induces enhanced anti-tumor capacity of murine CD8+ T cells. Eur J Immunol. 2017;47:1354-1367 pubmed publisher |
| Shan Q, Zeng Z, Xing S, Li F, Hartwig S, Gullicksrud J, et al. The transcription factor Runx3 guards cytotoxic CD8+ effector T cells against deviation towards follicular helper T cell lineage. Nat Immunol. 2017;18:931-939 pubmed publisher |
| Yu Q, Wang X, Fan X. A New Adjuvant MTOM Mediates Mycobacterium tuberculosis Subunit Vaccine to Enhance Th1-Type T Cell Immune Responses and IL-2+ T Cells. Front Immunol. 2017;8:585 pubmed publisher |
| Yin W, Song Y, Liu Q, Wu Y, He R. Topical treatment of all-trans retinoic acid inhibits murine melanoma partly by promoting CD8+ T-cell immunity. Immunology. 2017;152:287-297 pubmed publisher |
| Klann J, Remedios K, Kim S, Metz P, Lopez J, Mack L, et al. Talin Plays a Critical Role in the Maintenance of the Regulatory T Cell Pool. J Immunol. 2017;198:4639-4651 pubmed publisher |
| Miao T, Symonds A, Singh R, Symonds J, Ogbe A, Omodho B, et al. Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiation. J Exp Med. 2017;214:1787-1808 pubmed publisher |
| Olson M, Ulrich B, Hummel S, Khan I, Meuris B, Cherukuri Y, et al. Paracrine IL-2 Is Required for Optimal Type 2 Effector Cytokine Production. J Immunol. 2017;198:4352-4359 pubmed publisher |
| Muraoka D, Seo N, Hayashi T, Hyuga Amaike C, Okamori K, Tawara I, et al. Signal-transducing adaptor protein-2 promotes generation of functional long-term memory CD8+ T cells by preventing terminal effector differentiation. Oncotarget. 2017;8:30766-30780 pubmed publisher |
| Billeskov R, Wang Y, Solaymani Mohammadi S, Frey B, Kulkarni S, Andersen P, et al. Low Antigen Dose in Adjuvant-Based Vaccination Selectively Induces CD4 T Cells with Enhanced Functional Avidity and Protective Efficacy. J Immunol. 2017;198:3494-3506 pubmed publisher |
| González Pérez G, Lamousé Smith E. Gastrointestinal Microbiome Dysbiosis in Infant Mice Alters Peripheral CD8+ T Cell Receptor Signaling. Front Immunol. 2017;8:265 pubmed publisher |
| Ansa Addo E, Zhang Y, Yang Y, Hussey G, Howley B, Salem M, et al. Membrane-organizing protein moesin controls Treg differentiation and antitumor immunity via TGF-β signaling. J Clin Invest. 2017;127:1321-1337 pubmed publisher |
| Lu Y, Liu H, Bi Y, Yang H, Li Y, Wang J, et al. Glucocorticoid receptor promotes the function of myeloid-derived suppressor cells by suppressing HIF1α-dependent glycolysis. Cell Mol Immunol. 2018;15:618-629 pubmed publisher |
| Cho J, Lee H, Ko H, Yoon B, Choe J, Kim K, et al. The TLR7 agonist imiquimod induces anti-cancer effects via autophagic cell death and enhances anti-tumoral and systemic immunity during radiotherapy for melanoma. Oncotarget. 2017;8:24932-24948 pubmed publisher |
| Rogel A, Willoughby J, Buchan S, Leonard H, Thirdborough S, Al Shamkhani A. Akt signaling is critical for memory CD8+ T-cell development and tumor immune surveillance. Proc Natl Acad Sci U S A. 2017;114:E1178-E1187 pubmed publisher |
| Berlato C, Khan M, Schioppa T, Thompson R, Maniati E, Montfort A, et al. A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer. J Clin Invest. 2017;127:801-813 pubmed publisher |
| Zamarron B, Mergian T, Cho K, Martinez Santibañez G, Luan D, Singer K, et al. Macrophage Proliferation Sustains Adipose Tissue Inflammation in Formerly Obese Mice. Diabetes. 2017;66:392-406 pubmed publisher |
| Schock S, Chandra N, Sun Y, Irie T, Kitagawa Y, Gotoh B, et al. Induction of necroptotic cell death by viral activation of the RIG-I or STING pathway. Cell Death Differ. 2017;24:615-625 pubmed publisher |
| Aguilera T, Rafat M, Castellini L, Shehade H, Kariolis M, Hui A, et al. Reprogramming the immunological microenvironment through radiation and targeting Axl. Nat Commun. 2016;7:13898 pubmed publisher |
| Escalante N, Lemire P, Cruz Tleugabulova M, Prescott D, Mortha A, Streutker C, et al. The common mouse protozoa Tritrichomonas muris alters mucosal T cell homeostasis and colitis susceptibility. J Exp Med. 2016;213:2841-2850 pubmed |
| Müller A, Florek M, Kohrt H, Küpper N, Filatenkov A, Linderman J, et al. Blood Stem Cell Activity Is Arrested by Th1-Mediated Injury Preventing Engraftment following Nonmyeloablative Conditioning. J Immunol. 2016;197:4151-4162 pubmed |
| Hu Y, Kim J, He K, Wan Q, Kim J, Flach M, et al. Scramblase TMEM16F terminates T cell receptor signaling to restrict T cell exhaustion. J Exp Med. 2016;213:2759-2772 pubmed |
| Zhou Y, Weng X, Dou R, Tan X, Zhang T, Fang J, et al. Betulin from Hedyotis hedyotidea ameliorates concanavalin A-induced and T cell-mediated autoimmune hepatitis in mice. Acta Pharmacol Sin. 2017;38:201-210 pubmed publisher |
| Finsterbusch M, Hall P, Li A, Devi S, Westhorpe C, Kitching A, et al. Patrolling monocytes promote intravascular neutrophil activation and glomerular injury in the acutely inflamed glomerulus. Proc Natl Acad Sci U S A. 2016;113:E5172-81 pubmed publisher |
| Hwang S, Cobb D, Bhadra R, Youngblood B, Khan I. Blimp-1-mediated CD4 T cell exhaustion causes CD8 T cell dysfunction during chronic toxoplasmosis. J Exp Med. 2016;213:1799-818 pubmed publisher |
| Utzschneider D, Alfei F, Roelli P, Barras D, Chennupati V, Darbre S, et al. High antigen levels induce an exhausted phenotype in a chronic infection without impairing T cell expansion and survival. J Exp Med. 2016;213:1819-34 pubmed publisher |
| Xu X, Meng Q, Erben U, Wang P, Glauben R, Kuhl A, et al. Myeloid-derived suppressor cells promote B-cell production of IgA in a TNFR2-dependent manner. Cell Mol Immunol. 2017;14:597-606 pubmed publisher |
| Clarke D, Letendre C, Lecours M, Lemire P, Galbas T, Thibodeau J, et al. Group B Streptococcus Induces a Robust IFN-? Response by CD4(+) T Cells in an In Vitro and In Vivo Model. J Immunol Res. 2016;2016:5290604 pubmed publisher |
| Martins K, Cooper C, Stronsky S, Norris S, Kwilas S, Steffens J, et al. Adjuvant-enhanced CD4 T Cell Responses are Critical to Durable Vaccine Immunity. EBioMedicine. 2016;3:67-78 pubmed publisher |
| Harmon D, Srikakulapu P, Kaplan J, Oldham S, McSkimming C, Garmey J, et al. Protective Role for B-1b B Cells and IgM in Obesity-Associated Inflammation, Glucose Intolerance, and Insulin Resistance. Arterioscler Thromb Vasc Biol. 2016;36:682-91 pubmed publisher |
| Alam M, Gaida M, Bergmann F, Lasitschka F, Giese T, Giese N, et al. Selective inhibition of the p38 alternative activation pathway in infiltrating T cells inhibits pancreatic cancer progression. Nat Med. 2015;21:1337-43 pubmed publisher |
| Gabbita S, Johnson M, Kobritz N, Eslami P, Poteshkina A, Varadarajan S, et al. Oral TNFα Modulation Alters Neutrophil Infiltration, Improves Cognition and Diminishes Tau and Amyloid Pathology in the 3xTgAD Mouse Model. PLoS ONE. 2015;10:e0137305 pubmed publisher |
| Parnas O, Jovanovic M, Eisenhaure T, Herbst R, Dixit A, Ye C, et al. A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks. Cell. 2015;162:675-86 pubmed publisher |
| Vogel A, Brown D. Single-Dose CpG Immunization Protects Against a Heterosubtypic Challenge and Generates Antigen-Specific Memory T Cells. Front Immunol. 2015;6:327 pubmed publisher |
| Zhang W, Cho S, Xiang G, Min K, Yu Q, Jin J. Ginseng Berry Extract Promotes Maturation of Mouse Dendritic Cells. PLoS ONE. 2015;10:e0130926 pubmed publisher |
| Teng X, Tian M, Li J, Tan S, Yuan X, Yu Q, et al. Immunogenicity and protective efficacy of DMT liposome-adjuvanted tuberculosis subunit CTT3H vaccine. Hum Vaccin Immunother. 2015;11:1456-64 pubmed publisher |
| Watanabe S, Chan K, Wang J, Rivino L, Lok S, Vasudevan S. Dengue Virus Infection with Highly Neutralizing Levels of Cross-Reactive Antibodies Causes Acute Lethal Small Intestinal Pathology without a High Level of Viremia in Mice. J Virol. 2015;89:5847-61 pubmed publisher |
| Bradfute S, Anthony S, Stuthman K, Ayithan N, Tailor P, Shaia C, et al. Mechanisms of immunity in post-exposure vaccination against Ebola virus infection. PLoS ONE. 2015;10:e0118434 pubmed publisher |
| Biswas A, Bruder D, Wolf S, Jeron A, Mack M, Heimesaat M, et al. Ly6C(high) monocytes control cerebral toxoplasmosis. J Immunol. 2015;194:3223-35 pubmed publisher |
| Wang L, Le Mercier I, Putra J, Chen W, Liu J, Schenk A, et al. Disruption of the immune-checkpoint VISTA gene imparts a proinflammatory phenotype with predisposition to the development of autoimmunity. Proc Natl Acad Sci U S A. 2014;111:14846-51 pubmed publisher |
| Guéry L, Dubrot J, Lippens C, Brighouse D, Malinge P, Irla M, et al. Ag-presenting CpG-activated pDCs prime Th17 cells that induce tumor regression. Cancer Res. 2014;74:6430-40 pubmed publisher |
| Berkley A, Fink P. Cutting edge: CD8+ recent thymic emigrants exhibit increased responses to low-affinity ligands and improved access to peripheral sites of inflammation. J Immunol. 2014;193:3262-6 pubmed publisher |
| Vaitaitis G, Olmstead M, Waid D, Carter J, Wagner D. A CD40-targeted peptide controls and reverses type 1 diabetes in NOD mice. Diabetologia. 2014;57:2366-73 pubmed publisher |
| Bhadra R, Moretto M, Castillo J, Petrovas C, Ferrando Martinez S, Shokal U, et al. Intrinsic TGF-? signaling promotes age-dependent CD8+ T cell polyfunctionality attrition. J Clin Invest. 2014;124:2441-55 pubmed publisher |
| Nakashima C, Otsuka A, Kitoh A, Honda T, Egawa G, Nakajima S, et al. Basophils regulate the recruitment of eosinophils in a murine model of irritant contact dermatitis. J Allergy Clin Immunol. 2014;134:100-7 pubmed publisher |
| Berod L, Stüve P, Swallow M, Arnold Schrauf C, Kruse F, Gentilini M, et al. MyD88 signalling in myeloid cells is sufficient to prevent chronic mycobacterial infection. Eur J Immunol. 2014;44:1399-409 pubmed publisher |
| Orr M, Beebe E, Hudson T, Moon J, Fox C, Reed S, et al. A dual TLR agonist adjuvant enhances the immunogenicity and protective efficacy of the tuberculosis vaccine antigen ID93. PLoS ONE. 2014;9:e83884 pubmed publisher |
| Sun B, Hu X, Liu G, Ma B, Xu Y, Yang T, et al. Phosphatase Wip1 negatively regulates neutrophil migration and inflammation. J Immunol. 2014;192:1184-95 pubmed publisher |
| Bodhankar S, Chen Y, Vandenbark A, Murphy S, Offner H. Treatment of experimental stroke with IL-10-producing B-cells reduces infarct size and peripheral and CNS inflammation in wild-type B-cell-sufficient mice. Metab Brain Dis. 2014;29:59-73 pubmed publisher |
| Brinkhoff B, Ostroumov D, Heemcke J, Woller N, Gürlevik E, Manns M, et al. Microsphere priming facilitates induction of potent therapeutic T-cell immune responses against autochthonous liver cancers. Eur J Immunol. 2014;44:1213-24 pubmed publisher |
| Gower R, Boehler R, Azarin S, Ricci C, Leonard J, Shea L. Modulation of leukocyte infiltration and phenotype in microporous tissue engineering scaffolds via vector induced IL-10 expression. Biomaterials. 2014;35:2024-31 pubmed publisher |
| Wang S, Wu B, Xue J, Wang M, Chen R, Wang B. Nizatidine, a small molecular compound, enhances killed H5N1 vaccine cell-mediated responses and protects mice from lethal viral challenge. Hum Vaccin Immunother. 2014;10:461-8 pubmed publisher |
| Mollo S, Ingram J, Kress R, Zajac A, Harrington L. Virus-specific CD4 and CD8 T cell responses in the absence of Th1-associated transcription factors. J Leukoc Biol. 2014;95:705-713 pubmed |
| Richert L, Rynda Apple A, Harmsen A, Han S, Wiley J, Douglas T, et al. CD11c? cells primed with unrelated antigens facilitate an accelerated immune response to influenza virus in mice. Eur J Immunol. 2014;44:397-408 pubmed publisher |
| Mollo S, Zajac A, Harrington L. Temporal requirements for B cells in the establishment of CD4 T cell memory. J Immunol. 2013;191:6052-9 pubmed publisher |
| Jeong Y, Jeon B, Gu S, Cho S, Shin S, Chang J, et al. Differentiation of antigen-specific T cells with limited functional capacity during Mycobacterium tuberculosis infection. Infect Immun. 2014;82:132-9 pubmed publisher |
| Steinbach K, Piedavent M, Bauer S, Neumann J, Friese M. Neutrophils amplify autoimmune central nervous system infiltrates by maturing local APCs. J Immunol. 2013;191:4531-9 pubmed publisher |
| Fulton R, Weiss K, Pewe L, Harty J, Varga S. Aged mice exhibit a severely diminished CD8 T cell response following respiratory syncytial virus infection. J Virol. 2013;87:12694-700 pubmed publisher |
| Bodhankar S, Chen Y, Vandenbark A, Murphy S, Offner H. PD-L1 enhances CNS inflammation and infarct volume following experimental stroke in mice in opposition to PD-1. J Neuroinflammation. 2013;10:111 pubmed publisher |
| Kawashima H, Takatori H, Suzuki K, Iwata A, Yokota M, Suto A, et al. Tumor suppressor p53 inhibits systemic autoimmune diseases by inducing regulatory T cells. J Immunol. 2013;191:3614-23 pubmed publisher |
| Rowe A, Murray S, Raué H, Koguchi Y, Slifka M, Parker D. A cell-intrinsic requirement for NF-?B-inducing kinase in CD4 and CD8 T cell memory. J Immunol. 2013;191:3663-72 pubmed publisher |
| Zhao J, Fett C, Pewe L, Zhao J, Perlman S. Development of transgenic mice expressing a coronavirus-specific public CD4 T cell receptor. J Immunol Methods. 2013;396:56-64 pubmed publisher |
| Fujii W, Ashihara E, Hirai H, Nagahara H, Kajitani N, Fujioka K, et al. Myeloid-derived suppressor cells play crucial roles in the regulation of mouse collagen-induced arthritis. J Immunol. 2013;191:1073-81 pubmed publisher |
| Hu Z, Zhang W, Usherwood E. Regulatory CD8+ T cells associated with erosion of immune surveillance in persistent virus infection suppress in vitro and have a reversible proliferative defect. J Immunol. 2013;191:312-22 pubmed publisher |
| Hafalla J, Bauza K, Friesen J, Gonzalez Aseguinolaza G, Hill A, Matuschewski K. Identification of targets of CD8⺠T cell responses to malaria liver stages by genome-wide epitope profiling. PLoS Pathog. 2013;9:e1003303 pubmed publisher |
| Gelderblom M, Neumann M, Ludewig P, Bernreuther C, Krasemann S, Arunachalam P, et al. Deficiency in serine protease inhibitor neuroserpin exacerbates ischemic brain injury by increased postischemic inflammation. PLoS ONE. 2013;8:e63118 pubmed publisher |
| Lee S, Kim Y, Hwang S, Kim Y, Han I, Vinay D, et al. 4-1BB signal stimulates the activation, expansion, and effector functions of ?? T cells in mice and humans. Eur J Immunol. 2013;43:1839-48 pubmed publisher |
| Bodhankar S, Chen Y, Vandenbark A, Murphy S, Offner H. IL-10-producing B-cells limit CNS inflammation and infarct volume in experimental stroke. Metab Brain Dis. 2013;28:375-86 pubmed publisher |
| Torrado E, Fountain J, Robinson R, Martino C, Pearl J, Rangel Moreno J, et al. Differential and site specific impact of B cells in the protective immune response to Mycobacterium tuberculosis in the mouse. PLoS ONE. 2013;8:e61681 pubmed publisher |
| Gracias D, Stelekati E, Hope J, Boesteanu A, Doering T, Norton J, et al. The microRNA miR-155 controls CD8(+) T cell responses by regulating interferon signaling. Nat Immunol. 2013;14:593-602 pubmed publisher |
| Villegas Mendez A, de Souza J, Lavelle S, Gwyer Findlay E, Shaw T, Van Rooijen N, et al. IL-27 receptor signalling restricts the formation of pathogenic, terminally differentiated Th1 cells during malaria infection by repressing IL-12 dependent signals. PLoS Pathog. 2013;9:e1003293 pubmed publisher |
| Kidani Y, Elsaesser H, Hock M, Vergnes L, Williams K, Argus J, et al. Sterol regulatory element-binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity. Nat Immunol. 2013;14:489-99 pubmed publisher |
| Jayaraman P, Sada Ovalle I, Nishimura T, Anderson A, Kuchroo V, Remold H, et al. IL-1? promotes antimicrobial immunity in macrophages by regulating TNFR signaling and caspase-3 activation. J Immunol. 2013;190:4196-204 pubmed publisher |
| Liu B, Wang M, Wang X, Zhao D, Liu D, Liu J, et al. Liver sinusoidal endothelial cell lectin inhibits CTL-dependent virus clearance in mouse models of viral hepatitis. J Immunol. 2013;190:4185-95 pubmed publisher |
| Gahring L, Enioutina E, Myers E, Spangrude G, Efimova O, Kelley T, et al. Nicotinic receptor alpha7 expression identifies a novel hematopoietic progenitor lineage. PLoS ONE. 2013;8:e57481 pubmed publisher |
| Zeng J, See A, Phallen J, Jackson C, Belcaid Z, Ruzevick J, et al. Anti-PD-1 blockade and stereotactic radiation produce long-term survival in mice with intracranial gliomas. Int J Radiat Oncol Biol Phys. 2013;86:343-9 pubmed publisher |
| Le Huu D, Matsushita T, Jin G, Hamaguchi Y, Hasegawa M, Takehara K, et al. Donor-derived regulatory B cells are important for suppression of murine sclerodermatous chronic graft-versus-host disease. Blood. 2013;121:3274-83 pubmed publisher |
| Kwon H, Kim G, Kim Y, Hwang W, Jash A, Sahoo A, et al. Amelioration of experimental autoimmune encephalomyelitis by probiotic mixture is mediated by a shift in T helper cell immune response. Clin Immunol. 2013;146:217-27 pubmed publisher |
| Jessen B, Bode S, Ammann S, Chakravorty S, Davies G, Diestelhorst J, et al. The risk of hemophagocytic lymphohistiocytosis in Hermansky-Pudlak syndrome type 2. Blood. 2013;121:2943-51 pubmed publisher |
| Condotta S, Rai D, James B, Griffith T, Badovinac V. Sustained and incomplete recovery of naive CD8+ T cell precursors after sepsis contributes to impaired CD8+ T cell responses to infection. J Immunol. 2013;190:1991-2000 pubmed publisher |
| Yee N, Hamerman J. ?(2) integrins inhibit TLR responses by regulating NF-?B pathway and p38 MAPK activation. Eur J Immunol. 2013;43:779-92 pubmed publisher |
| Ma D, Suthar M, Kasahara S, Gale M, Clark E. CD22 is required for protection against West Nile virus Infection. J Virol. 2013;87:3361-75 pubmed publisher |
| Horikawa M, Weimer E, DiLillo D, Venturi G, Spolski R, Leonard W, et al. Regulatory B cell (B10 Cell) expansion during Listeria infection governs innate and cellular immune responses in mice. J Immunol. 2013;190:1158-68 pubmed publisher |
| Trujillo J, Fleming E, Perlman S. Transgenic CCL2 expression in the central nervous system results in a dysregulated immune response and enhanced lethality after coronavirus infection. J Virol. 2013;87:2376-89 pubmed publisher |
| Papadopoulos G, Weinberg E, Massari P, Gibson F, Wetzler L, Morgan E, et al. Macrophage-specific TLR2 signaling mediates pathogen-induced TNF-dependent inflammatory oral bone loss. J Immunol. 2013;190:1148-57 pubmed publisher |
| Beverley P, Ronan E, Lee L, Arnold I, Bolinger B, Powrie F, et al. Environmental effects on protection against Mycobacterium tuberculosis after immunization with Ad85A. Vaccine. 2013;31:1086-93 pubmed publisher |
| Visekruna A, Ritter J, Scholz T, Campos L, Guralnik A, Poncette L, et al. Tc9 cells, a new subset of CD8(+) T cells, support Th2-mediated airway inflammation. Eur J Immunol. 2013;43:606-18 pubmed publisher |
| Piao X, Komazawa Sakon S, Nishina T, Koike M, Piao J, Ehlken H, et al. c-FLIP maintains tissue homeostasis by preventing apoptosis and programmed necrosis. Sci Signal. 2012;5:ra93 pubmed publisher |
| Hoge J, Yan I, Jänner N, Schumacher V, Chalaris A, Steinmetz O, et al. IL-6 controls the innate immune response against Listeria monocytogenes via classical IL-6 signaling. J Immunol. 2013;190:703-11 pubmed publisher |
| Smithey M, Li G, Venturi V, Davenport M, Nikolich Zugich J. Lifelong persistent viral infection alters the naive T cell pool, impairing CD8 T cell immunity in late life. J Immunol. 2012;189:5356-66 pubmed publisher |
| Tosello Trampont A, Landes S, Nguyen V, Novobrantseva T, Hahn Y. Kuppfer cells trigger nonalcoholic steatohepatitis development in diet-induced mouse model through tumor necrosis factor-? production. J Biol Chem. 2012;287:40161-72 pubmed publisher |
| Walker J, Raué H, Slifka M. Characterization of CD8+ T cell function and immunodominance generated with an H2O2-inactivated whole-virus vaccine. J Virol. 2012;86:13735-44 pubmed publisher |
| Tewalt E, Cohen J, Rouhani S, Guidi C, Qiao H, Fahl S, et al. Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells. Blood. 2012;120:4772-82 pubmed publisher |
| Dahlin J, Feinstein R, Cui Y, Heyman B, Hallgren J. CD11c+ cells are required for antigen-induced increase of mast cells in the lung. J Immunol. 2012;189:3869-77 pubmed publisher |
| Koltsova E, Kim G, Lloyd K, Saris C, von Vietinghoff S, Kronenberg M, et al. Interleukin-27 receptor limits atherosclerosis in Ldlr-/- mice. Circ Res. 2012;111:1274-85 pubmed publisher |
| Moreau A, Noble A, Ratnasothy K, Chai J, Deltour L, Cuturi M, et al. Absence of Galectin-1 accelerates CD8⁺ T cell-mediated graft rejection. Eur J Immunol. 2012;42:2881-8 pubmed publisher |
| Kosinska A, Johrden L, Zhang E, Fiedler M, Mayer A, Wildner O, et al. DNA prime-adenovirus boost immunization induces a vigorous and multifunctional T-cell response against hepadnaviral proteins in the mouse and woodchuck model. J Virol. 2012;86:9297-310 pubmed publisher |
| Jung K, Kang M, Park C, Hyun Choi Y, Jeon Y, Park S, et al. Protective role of V-set and immunoglobulin domain-containing 4 expressed on kupffer cells during immune-mediated liver injury by inducing tolerance of liver T- and natural killer T-cells. Hepatology. 2012;56:1838-48 pubmed publisher |
| Movita D, Kreefft K, Biesta P, van Oudenaren A, Leenen P, Janssen H, et al. Kupffer cells express a unique combination of phenotypic and functional characteristics compared with splenic and peritoneal macrophages. J Leukoc Biol. 2012;92:723-33 pubmed publisher |
| Pham N, Badovinac V, Harty J. Epitope specificity of memory CD8+ T cells dictates vaccination-induced mortality in LCMV-infected perforin-deficient mice. Eur J Immunol. 2012;42:1488-99 pubmed publisher |
| Garidou L, Heydari S, Gossa S, McGavern D. Therapeutic blockade of transforming growth factor beta fails to promote clearance of a persistent viral infection. J Virol. 2012;86:7060-71 pubmed publisher |
| Wingender G, Stepniak D, Krebs P, Lin L, McBride S, Wei B, et al. Intestinal microbes affect phenotypes and functions of invariant natural killer T cells in mice. Gastroenterology. 2012;143:418-28 pubmed publisher |
| Iwata Y, Boström E, Menke J, Rabacal W, Morel L, Wada T, et al. Aberrant macrophages mediate defective kidney repair that triggers nephritis in lupus-susceptible mice. J Immunol. 2012;188:4568-80 pubmed publisher |
| Jiang X, Clark R, Liu L, Wagers A, Fuhlbrigge R, Kupper T. Skin infection generates non-migratory memory CD8+ T(RM) cells providing global skin immunity. Nature. 2012;483:227-31 pubmed publisher |
| Sodenkamp J, Waetzig G, Scheller J, Seegert D, Grötzinger J, Rose John S, et al. Therapeutic targeting of interleukin-6 trans-signaling does not affect the outcome of experimental tuberculosis. Immunobiology. 2012;217:996-1004 pubmed publisher |
| Cornish G, Tung S, Marshall D, Ley S, Seddon B. Tissue specific deletion of inhibitor of kappa B kinase 2 with OX40-Cre reveals the unanticipated expression from the OX40 locus in skin epidermis. PLoS ONE. 2012;7:e32193 pubmed publisher |
| Obata Y, Takahashi D, Ebisawa M, Kakiguchi K, Yonemura S, Jinnohara T, et al. Epithelial cell-intrinsic Notch signaling plays an essential role in the maintenance of gut immune homeostasis. J Immunol. 2012;188:2427-36 pubmed publisher |
| Rintoul J, Lemay C, Tai L, Stanford M, Falls T, de Souza C, et al. ORFV: a novel oncolytic and immune stimulating parapoxvirus therapeutic. Mol Ther. 2012;20:1148-57 pubmed publisher |
| Goicochea M, Zapata J, Bryant J, Davis H, Salvato M, Lukashevich I. Evaluation of Lassa virus vaccine immunogenicity in a CBA/J-ML29 mouse model. Vaccine. 2012;30:1445-52 pubmed publisher |
| Leepiyasakulchai C, Ignatowicz L, Pawlowski A, Kallenius G, Sköld M. Failure to recruit anti-inflammatory CD103+ dendritic cells and a diminished CD4+ Foxp3+ regulatory T cell pool in mice that display excessive lung inflammation and increased susceptibility to Mycobacterium tuberculosis. Infect Immun. 2012;80:1128-39 pubmed publisher |
| Takahara K, Tokieda S, Nagaoka K, Inaba K. Efficient capture of Candida albicans and zymosan by SIGNR1 augments TLR2-dependent TNF-? production. Int Immunol. 2012;24:89-96 pubmed publisher |
| Roffê E, Rothfuchs A, Santiago H, Marino A, Ribeiro Gomes F, Eckhaus M, et al. IL-10 limits parasite burden and protects against fatal myocarditis in a mouse model of Trypanosoma cruzi infection. J Immunol. 2012;188:649-60 pubmed publisher |
| Li Z, Zhang C, Zhou Z, Zhang J, Zhang J, Tian Z. Small intestinal intraepithelial lymphocytes expressing CD8 and T cell receptor ?? are involved in bacterial clearance during Salmonella enterica serovar Typhimurium infection. Infect Immun. 2012;80:565-74 pubmed publisher |
| Martinez R, Zhang N, Thomas S, Nandiwada S, Jenkins M, Binstadt B, et al. Arthritogenic self-reactive CD4+ T cells acquire an FR4hiCD73hi anergic state in the presence of Foxp3+ regulatory T cells. J Immunol. 2012;188:170-81 pubmed publisher |
| Fischer M, Davies M, Reider I, Heipertz E, Epler M, Sei J, et al. CD11b?, Ly6G? cells produce type I interferon and exhibit tissue protective properties following peripheral virus infection. PLoS Pathog. 2011;7:e1002374 pubmed publisher |
| Cheung R, Shen F, Phillips J, McGeachy M, Cua D, Heyworth P, et al. Activation of MDL-1 (CLEC5A) on immature myeloid cells triggers lethal shock in mice. J Clin Invest. 2011;121:4446-61 pubmed publisher |
| Yeh W, McWilliams I, Harrington L. Autoreactive Tbet-positive CD4 T cells develop independent of classic Th1 cytokine signaling during experimental autoimmune encephalomyelitis. J Immunol. 2011;187:4998-5006 pubmed publisher |
| Otsuka A, Kubo M, Honda T, Egawa G, Nakajima S, Tanizaki H, et al. Requirement of interaction between mast cells and skin dendritic cells to establish contact hypersensitivity. PLoS ONE. 2011;6:e25538 pubmed publisher |
| Voss E, Skuljec J, Gudi V, Skripuletz T, Pul R, Trebst C, et al. Characterisation of microglia during de- and remyelination: can they create a repair promoting environment?. Neurobiol Dis. 2012;45:519-28 pubmed publisher |
| Brincks E, Gurung P, Langlois R, Hemann E, Legge K, Griffith T. The magnitude of the T cell response to a clinically significant dose of influenza virus is regulated by TRAIL. J Immunol. 2011;187:4581-8 pubmed publisher |
| Massilamany C, Gangaplara A, Steffen D, Reddy J. Identification of novel mimicry epitopes for cardiac myosin heavy chain-? that induce autoimmune myocarditis in A/J mice. Cell Immunol. 2011;271:438-49 pubmed publisher |
| Elliott E, Van Ziffle J, Scapini P, Sullivan B, Locksley R, Lowell C. Deletion of Syk in neutrophils prevents immune complex arthritis. J Immunol. 2011;187:4319-30 pubmed publisher |
| Yu Y, Wang D, Liu C, Kaosaard K, Semple K, Anasetti C, et al. Prevention of GVHD while sparing GVL effect by targeting Th1 and Th17 transcription factor T-bet and ROR?t in mice. Blood. 2011;118:5011-20 pubmed publisher |
| Kastenmuller W, Gasteiger G, Subramanian N, Sparwasser T, Busch D, Belkaid Y, et al. Regulatory T cells selectively control CD8+ T cell effector pool size via IL-2 restriction. J Immunol. 2011;187:3186-97 pubmed publisher |
| Weiss K, Christiaansen A, Fulton R, Meyerholz D, Varga S. Multiple CD4+ T cell subsets produce immunomodulatory IL-10 during respiratory syncytial virus infection. J Immunol. 2011;187:3145-54 pubmed publisher |
| Feau S, Arens R, Togher S, Schoenberger S. Autocrine IL-2 is required for secondary population expansion of CD8(+) memory T cells. Nat Immunol. 2011;12:908-13 pubmed publisher |
| Chen Y, Wu S, Guo G, Fei L, Guo S, Yang C, et al. Programmed death (PD)-1-deficient mice are extremely sensitive to murine hepatitis virus strain-3 (MHV-3) infection. PLoS Pathog. 2011;7:e1001347 pubmed publisher |
| Ren X, Akiyoshi K, Vandenbark A, Hurn P, Offner H. Programmed death-1 pathway limits central nervous system inflammation and neurologic deficits in murine experimental stroke. Stroke. 2011;42:2578-83 pubmed publisher |
| Killebrew J, Perdue N, Kwan A, Thornton A, Shevach E, Campbell D. A self-reactive TCR drives the development of Foxp3+ regulatory T cells that prevent autoimmune disease. J Immunol. 2011;187:861-9 pubmed publisher |
| Milpied P, Massot B, Renand A, Diem S, Herbelin A, Leite de Moraes M, et al. IL-17-producing invariant NKT cells in lymphoid organs are recent thymic emigrants identified by neuropilin-1 expression. Blood. 2011;118:2993-3002 pubmed publisher |
| Ren X, Akiyoshi K, Dziennis S, Vandenbark A, Herson P, Hurn P, et al. Regulatory B cells limit CNS inflammation and neurologic deficits in murine experimental stroke. J Neurosci. 2011;31:8556-63 pubmed publisher |
| Skripuletz T, Miller E, Grote L, Gudi V, Pul R, Voss E, et al. Lipopolysaccharide delays demyelination and promotes oligodendrocyte precursor proliferation in the central nervous system. Brain Behav Immun. 2011;25:1592-606 pubmed publisher |
| Wojno E, Hosken N, Stumhofer J, O Hara A, Mauldin E, Fang Q, et al. A role for IL-27 in limiting T regulatory cell populations. J Immunol. 2011;187:266-73 pubmed publisher |
| Weinger J, Brosnan C, Loudig O, Goldberg M, Macian F, Arnett H, et al. Loss of the receptor tyrosine kinase Axl leads to enhanced inflammation in the CNS and delayed removal of myelin debris during experimental autoimmune encephalomyelitis. J Neuroinflammation. 2011;8:49 pubmed publisher |
| Massilamany C, Gangaplara A, Gardner D, Musser J, Steffen D, Somerville G, et al. TCA cycle inactivation in Staphylococcus aureus alters nitric oxide production in RAW 264.7 cells. Mol Cell Biochem. 2011;355:75-82 pubmed publisher |
| Prajeeth C, Haeberlein S, Sebald H, Schleicher U, Bogdan C. Leishmania-infected macrophages are targets of NK cell-derived cytokines but not of NK cell cytotoxicity. Infect Immun. 2011;79:2699-708 pubmed publisher |
| Stadnisky M, Xie X, Coats E, BULLOCK T, Brown M. Self MHC class I-licensed NK cells enhance adaptive CD8 T-cell viral immunity. Blood. 2011;117:5133-41 pubmed publisher |
| Diao J, Zhao J, Winter E, Cattral M. Tumors suppress in situ proliferation of cytotoxic T cells by promoting differentiation of Gr-1(+) conventional dendritic cells through IL-6. J Immunol. 2011;186:5058-67 pubmed publisher |
| Helmersson S, Stenstrom M, Leanderson T, Ivars F. Specific effect of immunomodulatory quinoline-3-carboxamide ABR-215757 in GM-CSF stimulated bone marrow cell cultures: block of initiation of proliferation of Gr-1+ cells. Int Immunopharmacol. 2011;11:1045-51 pubmed publisher |
| Zhang N, Bevan M. Dicer controls CD8+ T-cell activation, migration, and survival. Proc Natl Acad Sci U S A. 2010;107:21629-34 pubmed publisher |
| Chu Y, Vahl J, Kumar D, Heger K, Bertossi A, Wójtowicz E, et al. B cells lacking the tumor suppressor TNFAIP3/A20 display impaired differentiation and hyperactivation and cause inflammation and autoimmunity in aged mice. Blood. 2011;117:2227-36 pubmed publisher |
| Kim S, Steelman A, Koito H, Li J. Astrocytes promote TNF-mediated toxicity to oligodendrocyte precursors. J Neurochem. 2011;116:53-66 pubmed publisher |
| Fan J, Edsen Moore M, Turner L, Cook R, Legge K, Waldschmidt T, et al. Mechanisms by which chronic ethanol feeding limits the ability of dendritic cells to stimulate T-cell proliferation. Alcohol Clin Exp Res. 2011;35:47-59 pubmed publisher |
| Lee L, Baban D, Ronan E, Ragoussis J, Beverley P, Tchilian E. Chemokine gene expression in lung CD8 T cells correlates with protective immunity in mice immunized intra-nasally with Adenovirus-85A. BMC Med Genomics. 2010;3:46 pubmed publisher |
| Ito H, Hoshi M, Ohtaki H, Taguchi A, Ando K, Ishikawa T, et al. Ability of IDO to attenuate liver injury in alpha-galactosylceramide-induced hepatitis model. J Immunol. 2010;185:4554-60 pubmed publisher |
| Wu X, Gowda N, Gowda D. Plasmodium falciparum: differential merozoite dose requirements for maximal production of various inflammatory cytokines. Exp Parasitol. 2011;127:202-7 pubmed publisher |
| Fulton R, Meyerholz D, Varga S. Foxp3+ CD4 regulatory T cells limit pulmonary immunopathology by modulating the CD8 T cell response during respiratory syncytial virus infection. J Immunol. 2010;185:2382-92 pubmed publisher |
| Findlay E, Greig R, Stumhofer J, Hafalla J, de Souza J, Saris C, et al. Essential role for IL-27 receptor signaling in prevention of Th1-mediated immunopathology during malaria infection. J Immunol. 2010;185:2482-92 pubmed publisher |
| Matsushita T, Horikawa M, Iwata Y, Tedder T. Regulatory B cells (B10 cells) and regulatory T cells have independent roles in controlling experimental autoimmune encephalomyelitis initiation and late-phase immunopathogenesis. J Immunol. 2010;185:2240-52 pubmed publisher |
| Zhao J, Zhao J, Perlman S. T cell responses are required for protection from clinical disease and for virus clearance in severe acute respiratory syndrome coronavirus-infected mice. J Virol. 2010;84:9318-25 pubmed publisher |
| Marshall H, Prince A, Berg L, Welsh R. IFN-alpha beta and self-MHC divert CD8 T cells into a distinct differentiation pathway characterized by rapid acquisition of effector functions. J Immunol. 2010;185:1419-28 pubmed publisher |
| Shimada M, Yoshizaki S, Jounai N, Kondo A, Ichino M, Ryo A, et al. DNA vaccine expressing HIV-1 gp120/immunoglobulin fusion protein enhances cellular immunity. Vaccine. 2010;28:4920-7 pubmed publisher |
| Darrah P, Hegde S, Patel D, Lindsay R, Chen L, Roederer M, et al. IL-10 production differentially influences the magnitude, quality, and protective capacity of Th1 responses depending on the vaccine platform. J Exp Med. 2010;207:1421-33 pubmed publisher |
| Vega Ramos J, Alari Pahissa E, Valle J, Carrasco Marin E, Esplugues E, Borras M, et al. CD69 limits early inflammatory diseases associated with immune response to Listeria monocytogenes infection. Immunol Cell Biol. 2010;88:707-15 pubmed publisher |
| Gardner T, Chen Q, Jin Y, Ajuebor M. Toll-like receptor 3 ligand dampens liver inflammation by stimulating Valpha 14 invariant natural killer T cells to negatively regulate gammadeltaT cells. Am J Pathol. 2010;176:1779-89 pubmed publisher |
| Zellweger R, Prestwood T, Shresta S. Enhanced infection of liver sinusoidal endothelial cells in a mouse model of antibody-induced severe dengue disease. Cell Host Microbe. 2010;7:128-39 pubmed publisher |
| Tan A, Lam K. Pharmacologic inhibition of MEK-ERK signaling enhances Th17 differentiation. J Immunol. 2010;184:1849-57 pubmed publisher |
| Gulani J, Norbury C, Bonneau R, Beckwith C. The effect of Helicobacter hepaticus infection on immune responses specific to herpes simplex virus type 1 and characteristics of dendritic cells. Comp Med. 2009;59:534-44 pubmed |
| Fauriat C, Long E, Ljunggren H, Bryceson Y. Regulation of human NK-cell cytokine and chemokine production by target cell recognition. Blood. 2010;115:2167-76 pubmed publisher |
| Zou Y, Chen T, Han M, Wang H, Yan W, Song G, et al. Increased killing of liver NK cells by Fas/Fas ligand and NKG2D/NKG2D ligand contributes to hepatocyte necrosis in virus-induced liver failure. J Immunol. 2010;184:466-75 pubmed publisher |
| Kemball C, Harkins S, Whitmire J, Flynn C, Feuer R, Whitton J. Coxsackievirus B3 inhibits antigen presentation in vivo, exerting a profound and selective effect on the MHC class I pathway. PLoS Pathog. 2009;5:e1000618 pubmed publisher |
| Nijnik A, Pistolic J, Wyatt A, Tam S, Hancock R. Human cathelicidin peptide LL-37 modulates the effects of IFN-gamma on APCs. J Immunol. 2009;183:5788-98 pubmed publisher |
| Mildner A, Mack M, Schmidt H, Bruck W, Djukic M, Zabel M, et al. CCR2+Ly-6Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system. Brain. 2009;132:2487-500 pubmed publisher |
| Guarda G, Dostert C, Staehli F, Cabalzar K, Castillo R, Tardivel A, et al. T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes. Nature. 2009;460:269-73 pubmed publisher |
| Lindenstrøm T, Agger E, Korsholm K, Darrah P, Aagaard C, Seder R, et al. Tuberculosis subunit vaccination provides long-term protective immunity characterized by multifunctional CD4 memory T cells. J Immunol. 2009;182:8047-55 pubmed publisher |
| Li D, Molldrem J, Ma Q. LFA-1 regulates CD8+ T cell activation via T cell receptor-mediated and LFA-1-mediated Erk1/2 signal pathways. J Biol Chem. 2009;284:21001-10 pubmed publisher |
| Lee S, Salek Ardakani S, Mittler R, Croft M. Hypercostimulation through 4-1BB distorts homeostasis of immune cells. J Immunol. 2009;182:6753-62 pubmed publisher |
| Wu C, Rauch U, Korpos E, Song J, Loser K, Crocker P, et al. Sialoadhesin-positive macrophages bind regulatory T cells, negatively controlling their expansion and autoimmune disease progression. J Immunol. 2009;182:6508-16 pubmed publisher |
| Aldridge J, Moseley C, Boltz D, Negovetich N, Reynolds C, Franks J, et al. TNF/iNOS-producing dendritic cells are the necessary evil of lethal influenza virus infection. Proc Natl Acad Sci U S A. 2009;106:5306-11 pubmed publisher |
| Hamada H, Garcia Hernandez M, Reome J, Misra S, Strutt T, McKinstry K, et al. Tc17, a unique subset of CD8 T cells that can protect against lethal influenza challenge. J Immunol. 2009;182:3469-81 pubmed publisher |
| Reynoso E, Elpek K, Francisco L, Bronson R, Bellemare Pelletier A, Sharpe A, et al. Intestinal tolerance is converted to autoimmune enteritis upon PD-1 ligand blockade. J Immunol. 2009;182:2102-12 pubmed publisher |
| Jin N, Roark C, Miyahara N, Taube C, Aydintug M, Wands J, et al. Allergic airway hyperresponsiveness-enhancing gammadelta T cells develop in normal untreated mice and fail to produce IL-4/13, unlike Th2 and NKT cells. J Immunol. 2009;182:2002-10 pubmed publisher |
| Ito H, Ando K, Ishikawa T, Saito K, Takemura M, Imawari M, et al. Role of TNF-alpha produced by nonantigen-specific cells in a fulminant hepatitis mouse model. J Immunol. 2009;182:391-7 pubmed |
| Tsukimoto M, Nakatsukasa H, Sugawara K, Yamashita K, Kojima S. Repeated 0.5-Gy gamma irradiation attenuates experimental autoimmune encephalomyelitis with up-regulation of regulatory T cells and suppression of IL17 production. Radiat Res. 2008;170:429-36 pubmed |
| Salek Ardakani S, Moutaftsi M, Crotty S, Sette A, Croft M. OX40 drives protective vaccinia virus-specific CD8 T cells. J Immunol. 2008;181:7969-76 pubmed |
| Kraus Z, Haring J, Bishop G. TNF receptor-associated factor 5 is required for optimal T cell expansion and survival in response to infection. J Immunol. 2008;181:7800-9 pubmed |
| Liston A, Lu L, O Carroll D, Tarakhovsky A, Rudensky A. Dicer-dependent microRNA pathway safeguards regulatory T cell function. J Exp Med. 2008;205:1993-2004 pubmed publisher |
| Strick Marchand H, Masse G, Weiss M, Di Santo J. Lymphocytes support oval cell-dependent liver regeneration. J Immunol. 2008;181:2764-71 pubmed |
| Smith S, Ludwig M, Wohler J, Bullard D, Szalai A, Barnum S. Deletion of both ICAM-1 and C3 enhances severity of experimental autoimmune encephalomyelitis compared to C3-deficient mice. Neurosci Lett. 2008;442:158-60 pubmed publisher |
| Lauer P, Hanson B, Lemmens E, Liu W, Luckett W, Leong M, et al. Constitutive Activation of the PrfA regulon enhances the potency of vaccines based on live-attenuated and killed but metabolically active Listeria monocytogenes strains. Infect Immun. 2008;76:3742-53 pubmed publisher |
| Fulton R, Olson M, Varga S. Regulation of cytokine production by virus-specific CD8 T cells in the lungs. J Virol. 2008;82:7799-811 pubmed publisher |
| Cross J, Kott K, Miletic T, Johnson P. CD45 regulates TLR-induced proinflammatory cytokine and IFN-beta secretion in dendritic cells. J Immunol. 2008;180:8020-9 pubmed |
| Ito H, Ando K, Ishikawa T, Nakayama T, Taniguchi M, Saito K, et al. Role of Valpha14+ NKT cells in the development of Hepatitis B virus-specific CTL: activation of Valpha14+ NKT cells promotes the breakage of CTL tolerance. Int Immunol. 2008;20:869-79 pubmed publisher |
| Arens R, Wang P, Sidney J, Loewendorf A, Sette A, Schoenberger S, et al. Cutting edge: murine cytomegalovirus induces a polyfunctional CD4 T cell response. J Immunol. 2008;180:6472-6 pubmed |
| Whitmire J, Eam B, Whitton J. Tentative T cells: memory cells are quick to respond, but slow to divide. PLoS Pathog. 2008;4:e1000041 pubmed publisher |
| Lukens J, Cruise M, Lassen M, Hahn Y. Blockade of PD-1/B7-H1 interaction restores effector CD8+ T cell responses in a hepatitis C virus core murine model. J Immunol. 2008;180:4875-84 pubmed |
| Beaumier C, Mathew A, Bashyam H, Rothman A. Cross-reactive memory CD8(+) T cells alter the immune response to heterologous secondary dengue virus infections in mice in a sequence-specific manner. J Infect Dis. 2008;197:608-17 pubmed publisher |
| Li Z, Zhang M, Zhou C, Zhao X, Iijima N, Frankel F. Novel vaccination protocol with two live mucosal vectors elicits strong cell-mediated immunity in the vagina and protects against vaginal virus challenge. J Immunol. 2008;180:2504-13 pubmed |
| Rankin A, Reed A, Oh S, Cozzo Picca C, Guay H, Larkin J, et al. CD4+ T cells recognizing a single self-peptide expressed by APCs induce spontaneous autoimmune arthritis. J Immunol. 2008;180:833-41 pubmed |
| Barber A, Zhang T, Sentman C. Immunotherapy with chimeric NKG2D receptors leads to long-term tumor-free survival and development of host antitumor immunity in murine ovarian cancer. J Immunol. 2008;180:72-8 pubmed |
| Castilow E, Olson M, Meyerholz D, Varga S. Differential role of gamma interferon in inhibiting pulmonary eosinophilia and exacerbating systemic disease in fusion protein-immunized mice undergoing challenge infection with respiratory syncytial virus. J Virol. 2008;82:2196-207 pubmed |
| Menke J, Lucas J, Zeller G, Keir M, Huang X, Tsuboi N, et al. Programmed death 1 ligand (PD-L) 1 and PD-L2 limit autoimmune kidney disease: distinct roles. J Immunol. 2007;179:7466-77 pubmed |
| Tritt M, Sgouroudis E, d Hennezel E, Albanese A, Piccirillo C. Functional waning of naturally occurring CD4+ regulatory T-cells contributes to the onset of autoimmune diabetes. Diabetes. 2008;57:113-23 pubmed |
| Elftman M, Norbury C, Bonneau R, Truckenmiller M. Corticosterone impairs dendritic cell maturation and function. Immunology. 2007;122:279-90 pubmed |
| Priatel J, Chen X, Zenewicz L, Shen H, Harder K, Horwitz M, et al. Chronic immunodeficiency in mice lacking RasGRP1 results in CD4 T cell immune activation and exhaustion. J Immunol. 2007;179:2143-52 pubmed |
| Kapp J, Honjo K, Kapp L, Goldsmith K, Bucy R. Antigen, in the presence of TGF-beta, induces up-regulation of FoxP3gfp+ in CD4+ TCR transgenic T cells that mediate linked suppression of CD8+ T cell responses. J Immunol. 2007;179:2105-14 pubmed |
| Whitmire J, Eam B, Benning N, Whitton J. Direct interferon-gamma signaling dramatically enhances CD4+ and CD8+ T cell memory. J Immunol. 2007;179:1190-7 pubmed |
| Hernandez M, Shen L, Rock K. CD40-CD40 ligand interaction between dendritic cells and CD8+ T cells is needed to stimulate maximal T cell responses in the absence of CD4+ T cell help. J Immunol. 2007;178:2844-52 pubmed |
| Adams J, Webb M, Hu X, Staunton D, Barnum S. Disruption of the beta2-integrin CD11d (alphaDbeta2) gene fails to protect against experimental autoimmune encephalomyelitis. J Neuroimmunol. 2007;184:180-7 pubmed |
| Marie J, Liggitt D, Rudensky A. Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor. Immunity. 2006;25:441-54 pubmed |
| Zhao X, Zhang M, Li Z, Frankel F. Vaginal protection and immunity after oral immunization of mice with a novel vaccine strain of Listeria monocytogenes expressing human immunodeficiency virus type 1 gag. J Virol. 2006;80:8880-90 pubmed |
| Badovinac V, Messingham K, Griffith T, Harty J. TRAIL deficiency delays, but does not prevent, erosion in the quality of "helpless" memory CD8 T cells. J Immunol. 2006;177:999-1006 pubmed |
| Dhanji S, Chow M, Teh H. Self-antigen maintains the innate antibacterial function of self-specific CD8 T cells in vivo. J Immunol. 2006;177:138-46 pubmed |
| Nagai Y, Garrett K, Ohta S, Bahrun U, Kouro T, Akira S, et al. Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment. Immunity. 2006;24:801-12 pubmed |
| Chinen T, Kobayashi T, Ogata H, Takaesu G, Takaki H, Hashimoto M, et al. Suppressor of cytokine signaling-1 regulates inflammatory bowel disease in which both IFNgamma and IL-4 are involved. Gastroenterology. 2006;130:373-88 pubmed |
| Buhtoiarov I, Lum H, Berke G, Sondel P, Rakhmilevich A. Synergistic activation of macrophages via CD40 and TLR9 results in T cell independent antitumor effects. J Immunol. 2006;176:309-18 pubmed |
| Marquez M, Ellmeier W, Sanchez Guajardo V, Freitas A, Acuto O, Di Bartolo V. CD8 T cell sensory adaptation dependent on TCR avidity for self-antigens. J Immunol. 2005;175:7388-97 pubmed |
| Claassen E, Van der Kant P, Rychnavska Z, van Bleek G, Easton A, van der Most R. Activation and inactivation of antiviral CD8 T cell responses during murine pneumovirus infection. J Immunol. 2005;175:6597-604 pubmed |
| Yoo J, Omori M, Gyarmati D, Zhou B, Aye T, Brewer A, et al. Spontaneous atopic dermatitis in mice expressing an inducible thymic stromal lymphopoietin transgene specifically in the skin. J Exp Med. 2005;202:541-9 pubmed |
| Bennouna S, Denkers E. Microbial antigen triggers rapid mobilization of TNF-alpha to the surface of mouse neutrophils transforming them into inducers of high-level dendritic cell TNF-alpha production. J Immunol. 2005;174:4845-51 pubmed |
| Chackerian B, Lowy D, Schiller J. Conjugation of a self-antigen to papillomavirus-like particles allows for efficient induction of protective autoantibodies. J Clin Invest. 2001;108:415-23 pubmed |
| Price G, Ou R, Jiang H, Huang L, Moskophidis D. Viral escape by selection of cytotoxic T cell-resistant variants in influenza A virus pneumonia. J Exp Med. 2000;191:1853-67 pubmed |
| Williams R, Mauri C, Mason L, Marinova Mutafchieva L, Ross S, Feldmann M, et al. Therapeutic actions of cyclosporine and anti-tumor necrosis factor alpha in collagen-induced arthritis and the effect of combination therapy. Arthritis Rheum. 1998;41:1806-12 pubmed |
| Hunter C, Litton M, Remington J, Abrams J. Immunocytochemical detection of cytokines in the lymph nodes and brains of mice resistant or susceptible to toxoplasmic encephalitis. J Infect Dis. 1994;170:939-45 pubmed |
| Litton M, Sander B, Murphy E, O GARRA A, Abrams J. Early expression of cytokines in lymph nodes after treatment in vivo with Staphylococcus enterotoxin B. J Immunol Methods. 1994;175:47-58 pubmed |
| Abrams J, Roncarolo M, Yssel H, Andersson U, Gleich G, Silver J. Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples. Immunol Rev. 1992;127:5-24 pubmed |
