This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
IL-19 Monoclonal Antibody (RN19), eBioscience
catalog :
14-7191-81
quantity :
50 ug
price :
US 134.00
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
RN19
reactivity :
mouse
citations: 2
Reference
Cooley I, Chauhan V, Donneyz M, Marriott I. Astrocytes produce IL-19 in response to bacterial challenge and are sensitive to the immunosuppressive effects of this IL-10 family member. Glia. 2014;62:818-28 pubmed
Jordan W, Eskdale J, Boniotto M, Lennon G, Peat J, Campbell J, et al. Human IL-19 regulates immunity through auto-induction of IL-19 and production of IL-10. Eur J Immunol. 2005;35:1576-82 pubmed
product information
Product Type :
Antibody
Product Name :
IL-19 Monoclonal Antibody (RN19), eBioscience
Catalog # :
14-7191-81
Quantity :
50 ug
Price :
US 134.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
ELISA: 1-4 ug/mL
Species :
Mouse
Clone :
RN19
Isotype :
IgG1, kappa
Storage :
4 C
Description :
The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described.
Format :
Liquid
Applications w/Dilutions :
ELISA: 1-4 ug/mL
Aliases :
il 19; IL-10C; IL19; IL-19; ILN; Interleukin; interleukin 19; Interleukin19; interleukin-19; MDA1; MDA-1; melanoma differentiation associated protein-like protein; melanoma differentiation-associated protein-like protein; NG.1; ZMDA1
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA