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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD215 (IL-15Ra) Monoclonal Antibody (eBioJM7A4), eBioscience™
catalog :
14-7159-82
quantity :
100µg
price :
US 161
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
eBioJM7A4
reactivity :
human
application :
western blot, immunoprecipitation, flow cytometry
more info or order :
Invitrogen product webpage
citations: 7
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human
Alnabhan R, Madrigal A, Saudemont A. Differential activation of cord blood and peripheral blood natural killer cells by cytokines. Cytotherapy. 2015;17:73-85 pubmed publisher
Burns J, Song Y, Bujold M, Shimizu C, Kanegaye J, Tremoulet A, et al. Immune-monitoring in Kawasaki disease patients treated with infliximab and intravenous immunoglobulin. Clin Exp Immunol. 2013;174:337-44 pubmed publisher
Qin H, Lee I, Panagiotopoulos C, Wang X, Chu A, Utz P, et al. Natural killer cells from children with type 1 diabetes have defects in NKG2D-dependent function and signaling. Diabetes. 2011;60:857-66 pubmed publisher
Vámosi G, Bodnar A, Vereb G, Jenei A, Goldman C, Langowski J, et al. IL-2 and IL-15 receptor alpha-subunits are coexpressed in a supramolecular receptor cluster in lipid rafts of T cells. Proc Natl Acad Sci U S A. 2004;101:11082-7 pubmed
Dubois S, Mariner J, Waldmann T, Tagaya Y. IL-15Ralpha recycles and presents IL-15 In trans to neighboring cells. Immunity. 2002;17:537-47 pubmed
Anderson D, Kumaki S, Ahdieh M, Bertles J, Tometsko M, Loomis A, et al. Functional characterization of the human interleukin-15 receptor alpha chain and close linkage of IL15RA and IL2RA genes. J Biol Chem. 1995;270:29862-9 pubmed
Giri J, Kumaki S, Ahdieh M, Friend D, Loomis A, Shanebeck K, et al. Identification and cloning of a novel IL-15 binding protein that is structurally related to the alpha chain of the IL-2 receptor. EMBO J. 1995;14:3654-63 pubmed
product information
Product Type :
Antibody
Product Name :
CD215 (IL-15Ra) Monoclonal Antibody (eBioJM7A4), eBioscience™
Catalog # :
14-7159-82
Quantity :
100µg
Price :
US 161
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 0.5 µg/test, Immunoprecipitation: Assay-Dependent, Western Blot: Assay-Dependent
Species :
Human
Clone :
eBioJM7A4
Isotype :
IgG2b
Storage :
4° C
Description :
Interleukin 15 (IL-15RA) is a cytokine receptor that specifically binds IL-15 with high affinity. IL-15 regulates T and natural killer cell activation and proliferation. The IL-15 and IL-2 receptors share two subunits, IL-2R beta and IL-2R gamma, and IL-15RA is structurally related to IL-2RA, an additional IL-2-specific alpha subunit necessary for high affinity IL-2 binding. Unlike IL-2RA, IL-15RA is capable of binding IL-15 with high affinity independent of the other subunits. IL-15RA is thought to enhance cell proliferation and expression of apoptosis inhibitor Bcl-xL and Bcl-2.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.5 µg/test, Immunoprecipitation: Assay-Dependent, Western Blot: Assay-Dependent
Aliases :
AA690181; CD215; IL 15 receptor; IL 15 receptor subunit a; IL 15R; IL 15R alpha; IL 15R a; IL15 receptor; IL15 receptor subunit alpha; IL-15 receptor subunit alpha; IL15 receptor subunit a; IL15R; IL15R alpha; IL15R a; IL15RA; IL-15RA; IL-15R-alpha; Interleukin 15 receptor; interleukin 15 receptor alpha isoform EM2; interleukin 15 receptor alpha isoform IC2; interleukin 15 receptor alpha isoform IC3; interleukin 15 receptor alpha isoform IC4; interleukin 15 receptor alpha isoform IC5; interleukin 15 receptor alpha isoform IC6; interleukin 15 receptor alpha isoform IC7; interleukin 15 receptor alpha isoform IC8; interleukin 15 receptor subunit alpha; Interleukin 15 receptor subunit a; interleukin 15 receptor, alpha; interleukin 15 receptor, alpha chain; Interleukin-15 receptor subunit alpha; sIL 15R; sIL-15 receptor subunit alpha; sIL15R; sIL-15RA; sIL-15R-alpha; soluble IL 15R; soluble IL15R; Soluble interleukin-15 receptor subunit alpha
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA