This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
IL-6 Monoclonal Antibody (MQ2-39C3), eBioscience
catalog :
14-7068-81
quantity :
50 ug
price :
US 124.00
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
MQ2-39C3

The same clone is also sold as:
reactivity :
human
citations: 14
Reference
Alford M, Choi K, Trimble M, Masoudi H, Kalsi P, Pletzer D, et al. Murine Model of Sinusitis Infection for Screening Antimicrobial and Immunomodulatory Therapies. Front Cell Infect Microbiol. 2021;11:621081 pubmed publisher
Pringle E, Robinson C, McCormick C. Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication Interferes with mTORC1 Regulation of Autophagy and Viral Protein Synthesis. J Virol. 2019;93: pubmed publisher
Volpetti F, Garcia Cordero J, Maerkl S. A microfluidic platform for high-throughput multiplexed protein quantitation. PLoS ONE. 2015;10:e0117744 pubmed publisher
Lavoy E, Bosch J, Lowder T, Simpson R. Acute aerobic exercise in humans increases cytokine expression in CD27(-) but not CD27(+) CD8(+) T-cells. Brain Behav Immun. 2013;27:54-62 pubmed publisher
Gellatly S, Needham B, Madera L, Trent M, Hancock R. The Pseudomonas aeruginosa PhoP-PhoQ two-component regulatory system is induced upon interaction with epithelial cells and controls cytotoxicity and inflammation. Infect Immun. 2012;80:3122-31 pubmed publisher
Vohra P, Poxton I. Induction of cytokines in a macrophage cell line by proteins of Clostridium difficile. FEMS Immunol Med Microbiol. 2012;65:96-104 pubmed publisher
Fogal B, Yi T, Wang C, Rao D, Lebastchi A, Kulkarni S, et al. Neutralizing IL-6 reduces human arterial allograft rejection by allowing emergence of CD161+ CD4+ regulatory T cells. J Immunol. 2011;187:6268-80 pubmed publisher
Sauer U, Domnanich P, Preininger C. Protein chip for the parallel quantification of high and low abundant biomarkers for sepsis. Anal Biochem. 2011;419:46-52 pubmed publisher
Domnanich P, Peña D, Preininger C. Xanthan/chitosan gold chip for metal enhanced protein biomarker detection. Biosens Bioelectron. 2011;26:2559-65 pubmed publisher
Veltkamp M, van Moorsel C, Rijkers G, Ruven H, van den Bosch J, Grutters J. Toll-like receptor (TLR)-9 genetics and function in sarcoidosis. Clin Exp Immunol. 2010;162:68-74 pubmed publisher
Nijnik A, Pistolic J, Wyatt A, Tam S, Hancock R. Human cathelicidin peptide LL-37 modulates the effects of IFN-gamma on APCs. J Immunol. 2009;183:5788-98 pubmed publisher
Floriano P, Christodoulides N, Miller C, Ebersole J, Spertus J, Rose B, et al. Use of saliva-based nano-biochip tests for acute myocardial infarction at the point of care: a feasibility study. Clin Chem. 2009;55:1530-8 pubmed publisher
Gaines Das R, Poole S. The international standard for interleukin-6. Evaluation in an international collaborative study. J Immunol Methods. 1993;160:147-53 pubmed
Andersson J, Abrams J, Bjork L, Funa K, Litton M, Agren K, et al. Concomitant in vivo production of 19 different cytokines in human tonsils. Immunology. 1994;83:16-24 pubmed
product information
Product Type :
Antibody
Product Name :
IL-6 Monoclonal Antibody (MQ2-39C3), eBioscience
Catalog # :
14-7068-81
Quantity :
50 ug
Price :
US 124.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Human
Applications :
ELISA: 1 ug/mL
Species :
Human
Clone :
MQ2-39C3
Isotype :
IgG2a, kappa
Storage :
4 C
Description :
IL-6 is a gene that encodes a cytokine that plays a role in inflammation and the maturation of B cells. The protein produced by this gene is an endogenous pyrogen that can induce fever in people with autoimmune diseases or infections. The gene is primarily expressed at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2). Diseases associated with IL6 include Kaposi Sarcoma and Rheumatoid Arthritis, Systemic Juvenile.
Format :
Liquid
Applications w/Dilutions :
ELISA: 1 ug/mL
Aliases :
B-cell differentiation factor; B-cell hybridoma growth factor; B-cell stimulatory factor 2; BSF2; BSF-2; CDF; CHIL-6; CTL differentiation factor; cytokine; HGF; H-IL-6; HSF; hybridoma growth factor; Ifnb2; IFN-beta-2; Il6; IL-6; ILg6; ILN; interferon beta-2; Interleukin; interleukin 6; Interleukin 6 (interferon, beta 2); interleukin 6 precursor; interleukin BSF-2; interleukin HP-1; Interleukin6; Interleukin-6; interleukin-6 precursor; interleukin-6 protein; M-IL-6; prointerleukin 6; R-IL-6
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA