NFkB p50/p105 Polyclonal Antibody, eBioscience | Invitrogen 14-6732-81 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

NFkB p50/p105 Polyclonal Antibody, eBioscience

catalog :

14-6732-81

quantity :

50 ug

price :

US 166.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunoprecipitation

citations: 7

Reference
Hamdalla H, Ahmed R, Galaly S, Naguib I, Alghamdi B, Ahmed O, et al. Ameliorative Effect of Curcumin Nanoparticles against Monosodium Iodoacetate-Induced Knee Osteoarthritis in Rats. Mediators Inflamm. 2022;2022:8353472 pubmed publisher
Stratos I, Behrendt A, Anselm C, Gonzalez A, Mittlmeier T, Vollmar B. Inhibition of TNF-α Restores Muscle Force, Inhibits Inflammation, and Reduces Apoptosis of Traumatized Skeletal Muscles. Cells. 2022;11: pubmed publisher
Lianto P, Ogutu F, Zhang Y, He F, Che H. Inhibitory effects of quail egg on mast cells degranulation by suppressing PAR2-mediated MAPK and NF-kB activation. Food Nutr Res. 2018;62: pubmed publisher
Miyazaki Anzai S, Masuda M, Kohno S, Levi M, Shiozaki Y, Keenan A, et al. Simultaneous inhibition of FXR and TGR5 exacerbates atherosclerotic formation. J Lipid Res. 2018;59:1709-1713 pubmed publisher
Lu Y, Wang Q, Xue G, Bi E, Ma X, Wang A, et al. Th9 Cells Represent a Unique Subset of CD4+ T Cells Endowed with the Ability to Eradicate Advanced Tumors. Cancer Cell. 2018;33:1048-1060.e7 pubmed publisher
Yeo S, French R, Spada F, Clarkson R. Opposing roles of Nfkb2 gene products p100 and p52 in the regulation of breast cancer stem cells. Breast Cancer Res Treat. 2017;162:465-477 pubmed publisher
Liu Q, Zhu Y, Yong W, Sze N, Tan N, Ding J. Cutting Edge: Synchronization of IRF1, JunB, and C/EBPÎ² Activities during TLR3-TLR7 Cross-Talk Orchestrates Timely Cytokine Synergy in the Proinflammatory Response. J Immunol. 2015;195:801-5 pubmed publisher

product information

Product Type :

Antibody

Product Name :

NFkB p50/p105 Polyclonal Antibody, eBioscience

Catalog # :

14-6732-81

Quantity :

50 ug

Price :

US 166.00

Clonality :

Polyclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunohistochemistry: Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: 1:400

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

4 C

Description :

NF-kB is a nuclear transcription factor activated by various extra and intracellular stimuli such as cytokines, UV radiation, stress, in injury, and by bacterial and viral products. It is involved in regulation of various cellular events including cell growth, differentiation, proliferation, apoptosis and inflammation. NFKB1 (p50), a 50KDa functional sub-unit of NF-kB, is a member of Rel protein family. It is synthesized as a p105 precursor protein and consists of an N-terminal conserved RHD-region containing nuclear localization signal, DNA-binding and dimerization domains. NFKB1 (p50) forms homodimers or heterodimerizes with p65, forming the functional NF-kB factor. NFKB1 (p50) directs the nuclear translocation of NF-kB and is instrumental in its DNA-bidning. Pathological role of NF-kB has been suggested in AIDS, hematogenic cancer cell metastasis and rheumatoid arthritis.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry: Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: 1:400

Aliases :

CVID12; DKFZp686C01211; DNA-binding factor KBF1; EBP-1; KBF1; MGC54151; NF kappaB1; NF KB; NFkappaB; NF-kappaB; NF-kappa-B; NF-kappaB p50; NF-kappaB1; NF-kappa-B1 p84/NF-kappa-B1 p98; NF-kappabeta; NF-kB; NF-kB p50/p105; NFKB1; NF-KB1; NFKB-p105; NFKB-p50; nuclear factor; nuclear factor kappa b; nuclear factor kappa B subunit 1; nuclear factor kappa-B DNA binding subunit; nuclear factor kappaB p50; nuclear factor NF-kappa-B p105 subunit; Nuclear factor NF-kappa-B p50 subunit; nuclear factor of kappa light chain gene enhancer in B-cells 1, p105; nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105; nuclear factor-kappaB p50; p105; p50; p50 subunit of NF kappaB; p50 subunit of NF-kappaB; p50/p105