This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
NFkB p65 Polyclonal Antibody, eBioscience
catalog :
14-6731-81
quantity :
50 ug
price :
US 187.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 15
Reference
Anand A, Chandana M, Ghosh S, Das R, Singh N, Vaishalli P, et al. Significance of Plasmodium berghei Amino Acid Transporter 1 in Food Vacuole Functionality and Its Association with Cerebral Pathogenesis. Microbiol Spectr. 2023;11:e0494322 pubmed publisher
Chang J, Zhang W. Remifentanil modulates the TLR4‑mediated MMP‑9/TIMP1 balance and NF‑κB/STAT3 signaling in LPS‑induced A549 cells. Exp Ther Med. 2023;25:79 pubmed publisher
Hamdalla H, Ahmed R, Galaly S, Naguib I, Alghamdi B, Ahmed O, et al. Ameliorative Effect of Curcumin Nanoparticles against Monosodium Iodoacetate-Induced Knee Osteoarthritis in Rats. Mediators Inflamm. 2022;2022:8353472 pubmed publisher
Chandana M, Anand A, Ghosh S, Das R, Beura S, Jena S, et al. Malaria parasite heme biosynthesis promotes and griseofulvin protects against cerebral malaria in mice. Nat Commun. 2022;13:4028 pubmed publisher
Huang Y, Li S, Chen H, Feng L, Yuan W, Han T. Butorphanol reduces the neuronal inflammatory response and apoptosis via inhibition of p38/JNK/ATF2/p53 signaling. Exp Ther Med. 2022;23:229 pubmed publisher
Tang S, Fang C, Liu Y, Tang L, Xu Y. Anti-obesity and Anti-diabetic Effect of Ursolic Acid against Streptozotocin/High Fat Induced Obese in Diabetic Rats. J Oleo Sci. 2022;71:289-300 pubmed publisher
Sun X, Xiao L, Chen J, Chen X, Chen X, Yao S, et al. DNA methylation is involved in the pathogenesis of osteoarthritis by regulating CtBP expression and CtBP-mediated signaling. Int J Biol Sci. 2020;16:994-1009 pubmed publisher
Riffo Vasquez Y, Kanabar V, Keir S, E Lacerda R, Man F, Jackson D, et al. Modulation of allergic inflammation in the lung by a peptide derived from Mycobacteria tuberculosis chaperonin 60.1. Clin Exp Allergy. 2020;50:508-519 pubmed publisher
Akieda Asai S, Ma H, Date Y. Palmitic acid induces guanylin gene expression through the Toll-like receptor 4/nuclear factor-κB pathway in rat macrophages. Am J Physiol Cell Physiol. 2019;317:C1239-C1246 pubmed publisher
Lianto P, Ogutu F, Zhang Y, He F, Che H. Inhibitory effects of quail egg on mast cells degranulation by suppressing PAR2-mediated MAPK and NF-kB activation. Food Nutr Res. 2018;62: pubmed publisher
Lee D, Lee C, Park S, Yim M, Lee J, Choi G, et al. Anti-inhibitory potential of an ethanolic extract of Distromium decumbens on pro-inflammatory cytokine production in Pseudomonas aeruginosa lipopolysaccharide-stimulated nasal polyp-derived fibroblasts. Int J Mol Med. 2017;40:1950-1956 pubmed publisher
Ma J, Jiang D, Gong X, Shao W, Zhu Z, Xu W, et al. Free immunoglobulin light chain (FLC) promotes murine colitis and colitis-associated colon carcinogenesis by activating the inflammasome. Sci Rep. 2017;7:5165 pubmed publisher
Das D, Sengupta I, Sarkar N, Pal A, Saha D, Bandopadhyay M, et al. Anti-hepatitis B virus (HBV) response of imiquimod based toll like receptor 7 ligand in hbv-positive human hepatocelluar carcinoma cell line. BMC Infect Dis. 2017;17:76 pubmed publisher
Mieczkowski J, Kocyk M, Nauman P, Gabrusiewicz K, Sielska M, Przanowski P, et al. Down-regulation of IKKβ expression in glioma-infiltrating microglia/macrophages is associated with defective inflammatory/immune gene responses in glioblastoma. Oncotarget. 2015;6:33077-90 pubmed publisher
Park H, Lee D, Yim M, Choi Y, Park S, Seo S, et al. 3,3'-Diindolylmethane inhibits VEGF expression through the HIF-1α and NF-κB pathways in human retinal pigment epithelial cells under chemical hypoxic conditions. Int J Mol Med. 2015;36:301-8 pubmed publisher
product information
Product Type :
Antibody
Product Name :
NFkB p65 Polyclonal Antibody, eBioscience
Catalog # :
14-6731-81
Quantity :
50 ug
Price :
US 187.00
Clonality :
Polyclonal
Purity :
Affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
ChIP Assay: 2.5 ug/10^6 cells, Immunocytochemistry: 1:100, Immunohistochemistry: 1:1,000, Immunoprecipitation: Assay-Dependent, Western Blot: 1:1,000-1:2,000
Species :
Human, Mouse, Rat
Isotype :
IgG
Storage :
4 C
Description :
Nuclear factor kB p65 (NF-kB p65) is encoded by the RELA gene and is present on chromosome 11 in humans. NF-kB P65 is also known as RelA (v-rel avian reticuloendotheliosis viral oncogene homolog A) and belongs to the Rel family of proteins. It is one of the two subunits of NF-kB (Nuclear factor kappa-light-chain-enhancer of activated B cells) that heterodimerizes with the other subunits p50 or p52. However, binding of TNF alpha to its cognate receptor phosphorylates IKK which in turn phosphorylates I kB allowing proteasomal degradation of I kB. It specifically plays a key role in transcription of immunoglobulin k (kappa) gene in mature B-lymphoid cells.
Format :
Liquid
Applications w/Dilutions :
ChIP Assay: 2.5 ug/10^6 cells, Immunocytochemistry: 1:100, Immunohistochemistry: 1:1,000, Immunoprecipitation: Assay-Dependent, Western Blot: 1:1,000-1:2,000
Aliases :
avian reticuloendotheliosis viral (v-rel) oncogene homolog A; EBP-1; I79_021812; MGC131774; NF KB; NFkappaB p65; nf-kappa-b p65; NF-kappa-B p65delta3; NF-kappa-B transcription factor p65; NF-kappaB transcription factor p65 subunit; NFkB; NF-kB p65; NF-kB p65 subunit; nfkb rela; NFKB1; nfkb3; NFkB-p50; nuclear factor; nuclear factor kappa b; nuclear factor kappa B subunit p65; nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; p65; p65 NF kappaB; p65 NF-kappa B; p65 NFkB; P65 transcription factor; putative transcription factor p65 homolog; REL A; rel1; rela; RELA proto-oncogene, NF-kB subunit; rela.L; rela-a; Transcription factor p65; v-rel avian reticuloendotheliosis viral oncogene homolog A; v-rel avian reticuloendotheliosis viral oncogene homolog A L homeolog; v-rel reticuloendotheliosis viral oncogene homolog A; v-rel reticuloendotheliosis viral oncogene homolog A (avian); v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65; XELAEV_18022301mg; Xrel1; xrela
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA