This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
STRO-1 Monoclonal Antibody (STRO-1), eBioscience
catalog :
14-6688-80
quantity :
25 ug
price :
US 162.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
STRO-1
application :
immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section
citations: 47
Reference
Fahim I, Ishaque A, Ramzan F, Shamsuddin S, Ali A, Salim A, et al. Overexpression of OLIG2 and MYT1L Transcription Factors Enhance the Differentiation Potential of Human Mesenchymal Stem Cells into Oligodendrocytes. Curr Issues Mol Biol. 2023;45:4100-4123 pubmed publisher
Bai J, Ge G, Wang Q, Li W, Zheng K, Xu Y, et al. Engineering Stem Cell Recruitment and Osteoinduction via Bioadhesive Molecular Mimics to Improve Osteoporotic Bone-Implant Integration. Research (Wash D C). 2022;2022:9823784 pubmed publisher
Fan J, Li S, Wang D. MicroRNA-149 suppresses osteogenic differentiation of mesenchymal stem cells via inhibition of AKT1-dependent Twist1 phosphorylation. Cell Death Discov. 2022;8:2 pubmed publisher
Yamada S, Yassin M, Schwarz T, Hansmann J, Mustafa K. Induction of osteogenic differentiation of bone marrow stromal cells on 3D polyester-based scaffolds solely by subphysiological fluidic stimulation in a laminar flow bioreactor. J Tissue Eng. 2021;12:20417314211019375 pubmed publisher
Yan M, Nada O, Smeets R, Gosau M, Friedrich R, Kluwe L. Compare features of human dental pulp cells cultured from pulp tissues with and without cryopreservation. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2021;165:445-451 pubmed publisher
Chang H, Chen I, Wang Y, Chang M, Tsai Y, Lan W, et al. Regulation of the regenerative activity of dental pulp stem cells from exfoliated deciduous teeth (SHED) of children by TGF-β1 is associated with ALK5/Smad2, TAK1, p38 and MEK/ERK signaling. Aging (Albany NY). 2020;12:21253-21272 pubmed publisher
Yan M, Nada O, Kluwe L, Gosau M, Smeets R, Friedrich R. Expansion of Human Dental Pulp Cells In Vitro Under Different Cryopreservation Conditions. In Vivo. 2020;34:2363-2370 pubmed publisher
Zhu S, Liu Z, Yuan C, Lin Y, Yang Y, Wang H, et al. Bidirectional ephrinB2‑EphB4 signaling regulates the osteogenic differentiation of canine periodontal ligament stem cells. Int J Mol Med. 2020;45:897-909 pubmed publisher
Fu X, Feng Y, Shao B, Zhang Y. Activation of the ERK/Creb/Bcl‑2 pathway protects periodontal ligament stem cells against hydrogen peroxide‑induced oxidative stress. Mol Med Rep. 2019;19:3649-3657 pubmed publisher
Zhao X, Zhu B, Duan Y, Wang X, Li D. The Effect of Smoking Behavior on Alveolar Bone Marrow Mesenchymal Stem Cells of Clinical Implant Patient. Biomed Res Int. 2018;2018:7672695 pubmed publisher
Yan B, Zhang H, Dai T, Gu Y, Qiu X, Hu C, et al. Necrostatin-1 promotes ectopic periodontal tissue like structure regeneration in LPS-treated PDLSCs. PLoS ONE. 2018;13:e0207760 pubmed publisher
Xiao L, Xu S, Wang X, Jin Z, Wang J, Yang B, et al. Isolation and characterization of stem cells from differentially degenerated human lumbar zygapophyseal articular cartilage. Mol Med Rep. 2018;18:5751-5759 pubmed publisher
Pei D, Sun J, Zhu C, Tian F, Jiao K, Anderson M, et al. Contribution of Mitophagy to Cell-Mediated Mineralization: Revisiting a 50-Year-Old Conundrum. Adv Sci (Weinh). 2018;5:1800873 pubmed publisher
Kato M, Placencio Hickok V, Madhav A, Haldar S, Tripathi M, Billet S, et al. Heterogeneous cancer-associated fibroblast population potentiates neuroendocrine differentiation and castrate resistance in a CD105-dependent manner. Oncogene. 2019;38:716-730 pubmed publisher
Baharaghdam S, Yousefi M, Movasaghpour A, Solali S, Talebi M, Ahani Nahayati M, et al. Effects of Hypoxia on Biology of Human Leukemia T-cell Line (MOLT-4 cells) Co-cultured with Bone Marrow Mesenchymal Stem Cells. Avicenna J Med Biotechnol. 2018;10:62-68 pubmed
Prusinski Fernung L, Yang Q, Sakamuro D, Kumari A, Mas A, Al Hendy A. Endocrine disruptor exposure during development increases incidence of uterine fibroids by altering DNA repair in myometrial stem cells. Biol Reprod. 2018;99:735-748 pubmed publisher
Ventura Ferreira M, Bienert M, Muller K, Rath B, Goecke T, Opländer C, et al. Comprehensive characterization of chorionic villi-derived mesenchymal stromal cells from human placenta. Stem Cell Res Ther. 2018;9:28 pubmed publisher
Mas A, Prusinski L, Yang Q, Díaz Gimeno P, Stone L, Diamond M, et al. Role of Stro1+/CD44+ stem cells in myometrial physiology and uterine remodeling during pregnancy. Biol Reprod. 2017;96:70-80 pubmed publisher
Vega S, Liu E, Arvind V, Bushman J, Sung H, Becker M, et al. High-content image informatics of the structural nuclear protein NuMA parses trajectories for stem/progenitor cell lineages and oncogenic transformation. Exp Cell Res. 2017;351:11-23 pubmed publisher
Gong M, Antony S, Sakurai R, Liu J, Iacovino M, Rehan V. Bone marrow mesenchymal stem cells of the intrauterine growth-restricted rat offspring exhibit enhanced adipogenic phenotype. Int J Obes (Lond). 2016;40:1768-1775 pubmed publisher
Chen Y, Yao C, Huang C, Chang H, Young T. Hexosamine-Induced TGF-β Signaling and Osteogenic Differentiation of Dental Pulp Stem Cells Are Dependent on N-Acetylglucosaminyltransferase V. Biomed Res Int. 2015;2015:924397 pubmed publisher
Romagnoli C, Zonefrati R, Galli G, Puppi D, Pirosa A, Chiellini F, et al. In Vitro Behavior of Human Adipose Tissue-Derived Stem Cells on Poly(ε-caprolactone) Film for Bone Tissue Engineering Applications. Biomed Res Int. 2015;2015:323571 pubmed publisher
Zhou Z, Li B, Dong Z, Liu F, Zhang Y, Yu Y, et al. Nicotine deteriorates the osteogenic differentiation of periodontal ligament stem cells through ?7 nicotinic acetylcholine receptor regulating Wnt pathway. PLoS ONE. 2013;8:e83102 pubmed publisher
Fawzy El Sayed K, Dörfer C, Ungefroren H, Kassem N, Wiltfang J, Paris S. Effect of Emdogain enamel matrix derivative and BMP-2 on the gene expression and mineralized nodule formation of alveolar bone proper-derived stem/progenitor cells. J Craniomaxillofac Surg. 2014;42:568-76 pubmed publisher
Yang W, Wang J, Moore D, Liang H, Dooner M, Wu Q, et al. Ptpn11 deletion in a novel progenitor causes metachondromatosis by inducing hedgehog signalling. Nature. 2013;499:491-5 pubmed publisher
Kazemnejad S, Zarnani A, Khanmohammadi M, Mobini S. Chondrogenic differentiation of menstrual blood-derived stem cells on nanofibrous scaffolds. Methods Mol Biol. 2013;1058:149-69 pubmed publisher
Liu Y, Goldberg A, Dennis J, Gronowicz G, Kuhn L. One-step derivation of mesenchymal stem cell (MSC)-like cells from human pluripotent stem cells on a fibrillar collagen coating. PLoS ONE. 2012;7:e33225 pubmed publisher
Fawzy El Sayed K, Paris S, Becker S, Kassem N, Ungefroren H, Fandrich F, et al. Isolation and characterization of multipotent postnatal stem/progenitor cells from human alveolar bone proper. J Craniomaxillofac Surg. 2012;40:735-42 pubmed publisher
Helledie T, Dombrowski C, Rai B, Lim Z, Hin I, Rider D, et al. Heparan sulfate enhances the self-renewal and therapeutic potential of mesenchymal stem cells from human adult bone marrow. Stem Cells Dev. 2012;21:1897-910 pubmed publisher
Sun H, Zhang X, Chen X, Zhang C, Gao L, Feng Y, et al. Human umbilical cord blood-derived stromal cells are superior to human umbilical cord blood-derived mesenchymal stem cells in inducing myeloid lineage differentiation in vitro. Stem Cells Dev. 2012;21:1429-40 pubmed publisher
Guo W, Chen L, Gong K, Ding B, Duan Y, Jin Y. Heterogeneous dental follicle cells and the regeneration of complex periodontal tissues. Tissue Eng Part A. 2012;18:459-70 pubmed publisher
Hu G, Liu P, Feng J, Jin Y. Transplantation with bone marrow stromal cells promotes wound healing under chemotherapy through altering phenotypes. Int J Biol Sci. 2011;7:912-26 pubmed
Liao J, Al Shahrani M, Al Habib M, Tanaka T, Huang G. Cells isolated from inflamed periapical tissue express mesenchymal stem cell markers and are highly osteogenic. J Endod. 2011;37:1217-24 pubmed publisher
Lu W, Yu J, Zhang Y, Ji K, Zhou Y, Li Y, et al. Mixture of fibroblasts and adipose tissue-derived stem cells can improve epidermal morphogenesis of tissue-engineered skin. Cells Tissues Organs. 2012;195:197-206 pubmed publisher
Wang F, Yu M, Yan X, Wen Y, Zeng Q, Yue W, et al. Gingiva-derived mesenchymal stem cell-mediated therapeutic approach for bone tissue regeneration. Stem Cells Dev. 2011;20:2093-102 pubmed publisher
Wang L, Shen H, Zheng W, Tang L, Yang Z, Gao Y, et al. Characterization of stem cells from alveolar periodontal ligament. Tissue Eng Part A. 2011;17:1015-26 pubmed publisher
Arpornmaeklong P, Wang Z, Pressler M, Brown S, Krebsbach P. Expansion and characterization of human embryonic stem cell-derived osteoblast-like cells. Cell Reprogram. 2010;12:377-89 pubmed publisher
Rada T, Reis R, Gomes M. Distinct stem cells subpopulations isolated from human adipose tissue exhibit different chondrogenic and osteogenic differentiation potential. Stem Cell Rev. 2011;7:64-76 pubmed publisher
Arpornmaeklong P, Brown S, Wang Z, Krebsbach P. Phenotypic characterization, osteoblastic differentiation, and bone regeneration capacity of human embryonic stem cell-derived mesenchymal stem cells. Stem Cells Dev. 2009;18:955-68 pubmed publisher
Chiba H, Ishii G, Ito T, Aoyagi K, Sasaki H, Nagai K, et al. CD105-positive cells in pulmonary arterial blood of adult human lung cancer patients include mesenchymal progenitors. Stem Cells. 2008;26:2523-30 pubmed publisher
Nagase T, Muneta T, Ju Y, Hara K, Morito T, Koga H, et al. Analysis of the chondrogenic potential of human synovial stem cells according to harvest site and culture parameters in knees with medial compartment osteoarthritis. Arthritis Rheum. 2008;58:1389-98 pubmed publisher
Zhang S, Muneta T, Morito T, Mochizuki T, Sekiya I. Autologous synovial fluid enhances migration of mesenchymal stem cells from synovium of osteoarthritis patients in tissue culture system. J Orthop Res. 2008;26:1413-8 pubmed publisher
Nimura A, Muneta T, Koga H, Mochizuki T, Suzuki K, Makino H, et al. Increased proliferation of human synovial mesenchymal stem cells with autologous human serum: comparisons with bone marrow mesenchymal stem cells and with fetal bovine serum. Arthritis Rheum. 2008;58:501-10 pubmed publisher
Mochizuki T, Muneta T, Sakaguchi Y, Nimura A, Yokoyama A, Koga H, et al. Higher chondrogenic potential of fibrous synovium- and adipose synovium-derived cells compared with subcutaneous fat-derived cells: distinguishing properties of mesenchymal stem cells in humans. Arthritis Rheum. 2006;54:843-53 pubmed
Sakaguchi Y, Sekiya I, Yagishita K, Muneta T. Comparison of human stem cells derived from various mesenchymal tissues: superiority of synovium as a cell source. Arthritis Rheum. 2005;52:2521-9 pubmed
Alliot Licht B, Bluteau G, Magne D, Lopez Cazaux S, Lieubeau B, Daculsi G, et al. Dexamethasone stimulates differentiation of odontoblast-like cells in human dental pulp cultures. Cell Tissue Res. 2005;321:391-400 pubmed
Simmons P, Torok Storb B. Identification of stromal cell precursors in human bone marrow by a novel monoclonal antibody, STRO-1. Blood. 1991;78:55-62 pubmed
product information
Product Type :
Antibody
Product Name :
STRO-1 Monoclonal Antibody (STRO-1), eBioscience
Catalog # :
14-6688-80
Quantity :
25 ug
Price :
US 162.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Bovine, Human, Rat
Applications :
Flow Cytometry: 0.5 ug/test, Immunocytochemistry: 20 ug/mL, Immunohistochemistry (Frozen): Assay-Dependent
Species :
Bovine, Human, Rat
Clone :
STRO-1
Isotype :
IgM, lambda
Storage :
4 C
Description :
STRO-1 is a cell surface antigen expressed by stromal elements in human bone marrow. STRO-1 binds to approximately 10% of bone marrow mononuclear cells, greater than 95% of which are nucleated erythroid precursors, but does not react with committed progenitor cells (colony-forming unit granulocyte-macrophage (CFU-GM), erythroid bursts (BFU-E), and mixed colonies (CFU-Mix). From bone marrow cells, the frequency of fibroblast colony forming cells (CFU-F) is enriched approximately 100-fold in the STRO-1-positive/Glycophorin A-negative population than in the STRO-1-positive/Glycophorin A-positive population. When plated under long-term BM culture conditions, STRO-1-positive cells generate adherent cell layers containing multiple stromal cell types, including adipocytes, smooth muscle cells, and fibroblastic elements. A STRO-1-positive enriched subset of marrow cells is capable of differentiating into multiple mesenchymal lineages including hematopoiesis-supportive stromal cells with a vascular smooth muscle-like phenotype, adipocytes, osteoblasts and chondrocytes. STRO-1 is a valuable antibody for the identification, isolation and functional characterization of human bone marrow stromal cell precursors.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.5 ug/test, Immunocytochemistry: 20 ug/mL, Immunohistochemistry (Frozen): Assay-Dependent
Aliases :
STRO1
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA