Lactoferrin Monoclonal Antibody (B97), eBioscience | Invitrogen 14-6604-82 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Lactoferrin Monoclonal Antibody (B97), eBioscience

catalog :

14-6604-82

quantity :

100 ug

price :

US 313.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

B97

The same clone is also sold as:

Santa Cruz Biotechnology: sc-53498 HRP, sc-53498, sc-53498 AC

reactivity :

human

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 4

Reference
Actor J, Hwang S, Kruzel M. Lactoferrin as a natural immune modulator. Curr Pharm Des. 2009;15:1956-73 pubmed
Siebert P, Huang B. Identification of an alternative form of human lactoferrin mRNA that is expressed differentially in normal tissues and tumor-derived cell lines. Proc Natl Acad Sci U S A. 1997;94:2198-203 pubmed
Green I, Kirkpatrick C, Dale D. Lactoferrin--specific localization in the nuclei of human polymorphonuclear neutrophilic leukocytes. Proc Soc Exp Biol Med. 1971;137:1311-7 pubmed
Butler T, Grossi C, Canessa A, Pistoia V, Barton J. Immunoreactive lactoferrin in resting, activated, and neoplastic lymphocytes. Leuk Res. 1990;14:441-7 pubmed

product information

Product Type :

Antibody

Product Name :

Lactoferrin Monoclonal Antibody (B97), eBioscience

Catalog # :

14-6604-82

Quantity :

100 ug

Price :

US 313.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Immunohistochemistry (Paraffin): Assay-Dependent, Western Blot: 10 ug/mL

Species :

Human

Clone :

B97

Isotype :

IgG1

Storage :

4 C

Description :

Lactoferrin (LF) is an iron binding glycoprotein. LF consists of a single polypeptide chain (approximately 80 kDa) folded into two structurally homologous lobes, each of which can reversibly bind one ferric ion (Fe3+). LF is found in external fluids, including milk and mucosal secretions, and is a prominent component of secondary granuals of neutrophils. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. LTF acts as a major first line defense against microbial infections, partly due to its ability to efficiently bind to and hence remove Fe3+ from the environment, but studies have also shown that LTF possesses bactericidal properties and proteolytic activity, capable of cleaving arginine-rich sequences within microbial proteins. Three isoforms of LTF have been identified: LTF-alpha, LTF-beta and LTF-gamma and receptors for LTF are expressed in the gastrointestinal tract, by macrophages, lymphocytes, neutrophils and platelets and also by some bacteria.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): Assay-Dependent, Western Blot: 10 ug/mL

Aliases :

Bovine Lactoferrin; CKRX; Csp82; epididymis luminal protein 110; GIG12; Growth-inhibiting protein 12; HEL110; HLF2; Kaliocin 1; Kaliocin1; kaliocin-1; lactoferricin; Lactoferricin H; Lactoferricin-B; Lactoferricin-H; Lactoferrin; lactoferroxin; LactoferroxinA; Lactoferroxin-A; LactoferroxinB; Lactoferroxin-B; LactoferroxinC; Lactoferroxin-C; Lactotransferrin; LF; Lfcin H; Lfcin-B; LfcinH; Lfcin-H; LTF; minisatellite 10r detected by probe MMS10; MMS10R; Ms10r; N lobe; neutrophil lactoferrin; talalactoferrin