Cytochrome C Monoclonal Antibody (6H2), eBioscience | Invitrogen 14-6601-82 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Cytochrome C Monoclonal Antibody (6H2), eBioscience

catalog :

14-6601-82

quantity :

100 ug

price :

US 233.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6H2

The same clone is also sold as:

Santa Cruz Biotechnology: sc-13561 AC, sc-13561

reactivity :

human, mouse, rat

application :

immunoprecipitation, flow cytometry

citations: 4

Reference
Cooley J, Javkhlan N, Wilson J, Foster D, Edelman B, Ortiz L, et al. Inhibition of antiapoptotic BCL-2 proteins with ABT-263 induces fibroblast apoptosis, reversing persistent pulmonary fibrosis. JCI Insight. 2023;8: pubmed publisher
Moretti F, Giardino G, Attenborough T, Gkazi A, Margetts B, la Marca G, et al. Metabolite and thymocyte development defects in ADA-SCID mice receiving enzyme replacement therapy. Sci Rep. 2021;11:23221 pubmed publisher
Mohapatra A, Kumar S, Satapathy A, Ravindran B. Caspase dependent programmed cell death in developing embryos: a potential target for therapeutic intervention against pathogenic nematodes. PLoS Negl Trop Dis. 2011;5:e1306 pubmed publisher
Goshorn S, Retzel E, Jemmerson R. Common structural features among monoclonal antibodies binding the same antigenic region of cytochrome c. J Biol Chem. 1991;266:2134-42 pubmed

product information

Product Type :

Antibody

Product Name :

Cytochrome C Monoclonal Antibody (6H2), eBioscience

Catalog # :

14-6601-82

Quantity :

100 ug

Price :

US 233.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

Flow Cytometry: Assay-Dependent, Immunoprecipitation: Assay-Dependent

Species :

Human, Mouse, Rat

Clone :

6H2

Isotype :

IgG1, kappa

Storage :

4 C

Description :

Cytochrome C is an electron transporting protein that resides within the intermembrane space of the mitochondria, where it plays a critical role in oxidative phosphorylation and the production of cellular ATP. Release of cytochrome C from the mitochondria to the cytosol is triggered by apoptotic stimuli. In the cytoplasm, the cytochrome C binds apoptotic protease activating factor which activates the apoptotic initiator procaspase 9. Cytosolic cytochrome C functions in the activation of caspase 3, an ICE family molecule that is a key effector of apoptosis.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-Dependent, Immunoprecipitation: Assay-Dependent

Aliases :

CG17903; CG17903-PA; CG17903-PB; CRF; CYC; CYC2; Cycs; CYCSA; Cyct-c-p; Cyt c; cyt c-p; cyt.c; CytC; Cyt-c; CYTC2; Cyt-c2; CytC-2; cyt-c-p; cytC-p; Cyt-c-p-PA; Cyt-c-p-PB; Cytochrome c; cytochrome c DC4; Cytochrome c proximal; Cytochrome C, expressed in somatic tissues; cytochrome c, somatic; Cytochrome c-2; cytochrome c-like; cytochrome c-like protein; Cytochrome c-proximal; cytochrome-c-p; Cytochrome-c-proximal; DC4; dCyt.C-p; DMc01; Dmel CG17903; Dmel_CG17903; hc1; HCS; l(2)k13905; lethal (2) k13905; LOC100341175; LOC100357840; MGC128356 protein; pDMc01; RH17228p; THC4