This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
alpha-Fetoprotein Monoclonal Antibody (AFP3), eBioscience
catalog :
14-6583-82
quantity :
100 ug
price :
US 520.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
AFP3
reactivity :
human
application :
western blot, immunocytochemistry
citations: 5
Reference
Kamand M, Ilieva M, Forsberg S, Thomassen M, Svenningsen A, Meyer M, et al. Generation of autism spectrum disorder patient-derived iPSC line SDUKIi004-A. Stem Cell Res. 2020;49:102038 pubmed publisher
Wang S, Liu Z, Ye Y, Li B, Liu T, Zhang W, et al. Ectopic hTERT expression facilitates reprograming of fibroblasts derived from patients with Werner syndrome as a WS cellular model. Cell Death Dis. 2018;9:923 pubmed publisher
Liu S, Li N, Yu X, Xiao X, Cheng K, Hu J, et al. Expression of intercellular adhesion molecule 1 by hepatocellular carcinoma stem cells and circulating tumor cells. Gastroenterology. 2013;144:1031-1041.e10 pubmed publisher
Lazarevich N. Molecular mechanisms of alpha-fetoprotein gene expression. Biochemistry (Mosc). 2000;65:117-33 pubmed
Kuo C, Fu J, Yeh M, Su S, Lee C. Generation of monoclonal antibodies to alpha-fetoprotein and application in solid-phase enzyme immunoassay. Biotechnol Appl Biochem. 1989;11:96-104 pubmed
product information
Product Type :
Antibody
Product Name :
alpha-Fetoprotein Monoclonal Antibody (AFP3), eBioscience
Catalog # :
14-6583-82
Quantity :
100 ug
Price :
US 520.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Immunocytochemistry: 1-10 ug/mL, Western Blot: 1-10 ug/mL
Species :
Human
Clone :
AFP3
Isotype :
IgG1, kappa
Storage :
4 C
Description :
AFP (Alpha Fetoprotein) is a major plasma protein produced by the yolk sac, intestinal tract and the liver during fetal life. AFP expression in adults is often associated with hepatoma or teratoma. However, hereditary persistence of AFP may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and AFP and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. AFP is found in monomeric, dimeric, and trimeric forms. AFP can also bind to copper ions, nickel ions, fatty acids and bilirubin. The level of AFP in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. High level of serum AFP has been identified in patients with hepatocellular carcinomas (HCC), teratoblastoma, colorectal cancer, pancreatic cancer, and germ cell neoplasms.
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 1-10 ug/mL, Western Blot: 1-10 ug/mL
Aliases :
a fetoglobulin; a fetoprotein; Afp; AFPD; Alpha fetoglobulin; alpha fetoprotein; alpha-1-fetoprotein; Alpha-fetoglobulin; alpha-fetoprotein; alpha-fetoprotein precursor; alpha-foetoprotein; chloride intracellular channel 6; FETA; fetoglobulin; fetoprotein; HPAFP; a fetoglobulin; a fetoprotein
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA