Chromogranin A Monoclonal Antibody (LK2H10), eBioscience™ | Invitrogen 14-6549-93 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Chromogranin A Monoclonal Antibody (LK2H10), eBioscience™

catalog :

14-6549-93

quantity :

100µl

price :

US 229.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

LK2H10

reactivity :

human

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 5

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 1c	Maina P, Shao P, Liu Q, Fazli L, Tyler S, Nasir M, et al. c-MYC drives histone demethylase PHF8 during neuroendocrine differentiation and in castration-resistant prostate cancer. Oncotarget. 2016;7:75585-75602 pubmed publisher
	Hedborg F, Fischer Colbrie R, Ostlin N, Sandstedt B, Tran M, Maxwell P. Differentiation in neuroblastoma: diffusion-limited hypoxia induces neuro-endocrine secretory protein 55 and other markers of a chromaffin phenotype. PLoS ONE. 2010;5: pubmed publisher
	Wilson B, Lloyd R. Detection of chromogranin in neuroendocrine cells with a monoclonal antibody. Am J Pathol. 1984;115:458-68 pubmed
	Chang T, Li C, Smithson W. Immunocytochemical study of small round cell tumors in routinely processed specimens. Arch Pathol Lab Med. 1989;113:1343-8 pubmed
	Wirnsberger G, Becker H, Ziervogel K, Hofler H. Diagnostic immunohistochemistry of neuroblastic tumors. Am J Surg Pathol. 1992;16:49-57 pubmed

product information

Product Type :

Antibody

Product Name :

Chromogranin A Monoclonal Antibody (LK2H10), eBioscience™

Catalog # :

14-6549-93

Quantity :

100µl

Price :

US 229.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Immunohistochemistry (Paraffin): 1:1000, Western Blot: Assay-Dependent

Species :

Human

Clone :

LK2H10

Isotype :

IgG1, kappa

Storage :

4° C

Description :

Chromogranin A (CHGA) is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocine cells. CHGA is a precursor to three biologically active peptides: vasostatin, pancreastatin, and parastatin. These peptides act as autocine or paracrine negative modulators of the neuroendocrine system. CHGA is an excellent marker for carcinoid tumors, pheo-chromocytomas, paragangliomas, and other neuro-endocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:1000, Western Blot: Assay-Dependent

Aliases :

CTNNB, DKFZp686D02253, FLJ25606, FLJ37923