This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Synaptophysin Monoclonal Antibody (EP10), eBioscience
catalog :
14-6525-37
quantity :
2 mg
price :
US 1474.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
EP10
reactivity :
Chinese hamsters, human
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 4
Reference
Wilson M, Thunemann M, Liu X, Lu Y, Puppo F, Adams J, et al. Multimodal monitoring of human cortical organoids implanted in mice reveal functional connection with visual cortex. Nat Commun. 2022;13:7945 pubmed publisher
Giandomenico S, Mierau S, Gibbons G, Wenger L, Masullo L, Sit T, et al. Cerebral organoids at the air-liquid interface generate diverse nerve tracts with functional output. Nat Neurosci. 2019;22:669-679 pubmed publisher
Dell Anno M, Wang X, Onorati M, Li M, Talpo F, Sekine Y, et al. Human neuroepithelial stem cell regional specificity enables spinal cord repair through a relay circuit. Nat Commun. 2018;9:3419 pubmed publisher
Arthur C, Stowell M. Structure of synaptophysin: a hexameric MARVEL-domain channel protein. Structure. 2007;15:707-14 pubmed
product information
Product Type :
Antibody
Product Name :
Synaptophysin Monoclonal Antibody (EP10), eBioscience
Catalog # :
14-6525-37
Quantity :
2 mg
Price :
US 1474.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Hamster, Human
Applications :
Immunocytochemistry: Assay-Dependent, Immunohistochemistry (Paraffin): 5 ug/mL, Immunoprecipitation: Assay-Dependent, Western Blot: 5 ug/mL
Species :
Hamster, Human
Clone :
EP10
Isotype :
IgG1, kappa
Storage :
4 C
Description :
Synaptophysin is a calcium-binding and integral membrane glycoprotein present in presynaptic vesicles in almost all neurons. Synaptophysin has four transmembrane domains and it forms a complex with dynamin at high calcium concentrations suggesting an involvement in synaptic vesicle endocytosis. It is also involved in the regulation of short-term and long-term synaptic plasticity. Synaptophysin is currently the most widely used marker for nerve terminals and for differentiating neuroendocrine tumors. Mutations in the gene can result in mental retardation, X-linked 96.
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: Assay-Dependent, Immunohistochemistry (Paraffin): 5 ug/mL, Immunoprecipitation: Assay-Dependent, Western Blot: 5 ug/mL
Aliases :
A230093K24Rik; AI848995; BM89 antigen; I79_012252; Major synaptic vesicle protein p38; MRX96; MRXSYP; p38; Syn; Synaptophysin; Syp; Syp I; Syp1
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA