product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Myosin 4 Monoclonal Antibody (MF20), eBioscience
catalog :
14-6503-82
quantity :
100 µg
price :
US 340.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
MF20
reactivity :
guinea pig, human, mouse, rat, dogs, bovine, chimpanzee, zebrafish , domestic rabbit
application :
western blot, immunocytochemistry, immunohistochemistry - frozen section
more info or order :
citations: 43
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; zebrafish ; 1:75; loading ...; fig s2c
Marín Juez R, Marass M, Gauvrit S, Rossi A, Lai S, Materna S, et al. Fast revascularization of the injured area is essential to support zebrafish heart regeneration. Proc Natl Acad Sci U S A. 2016;113:11237-11242 pubmed
Meng J, Lv Z, Chen X, Sun C, Jin C, Ding K, et al. LBP1C-2 from Lycium barbarum maintains skeletal muscle satellite cell pool by interaction with FGFR1. iScience. 2023;26:106573 pubmed publisher
Xiao C, Hou J, Wang F, Song Y, Zheng J, Luo L, et al. Endothelial Brg1 fine-tunes Notch signaling during zebrafish heart regeneration. NPJ Regen Med. 2023;8:21 pubmed publisher
Juan T, Ribeiro da Silva A, Cardoso B, Lim S, Charteau V, Stainier D. Multiple pkd and piezo gene family members are required for atrioventricular valve formation. Nat Commun. 2023;14:214 pubmed publisher
Zhang Y, Beketaev I, Ma Y, Wang J. Sumoylation-deficient phosphoglycerate mutase 2 impairs myogenic differentiation. Front Cell Dev Biol. 2022;10:1052363 pubmed publisher
Jacquier A, Risson V, Simonet T, Roussange F, Lacoste N, Ribault S, et al. Severe congenital myasthenic syndromes caused by agrin mutations affecting secretion by motoneurons. Acta Neuropathol. 2022;144:707-731 pubmed publisher
Stephan A, Graça F, Hunt L, Demontis F. Electroporation of Small Interfering RNAs into Tibialis Anterior Muscles of Mice. Bio Protoc. 2022;12: pubmed publisher
Al Zaeed N, Budai Z, Szondy Z, Sarang Z. TAM kinase signaling is indispensable for proper skeletal muscle regeneration in mice. Cell Death Dis. 2021;12:611 pubmed publisher
Bassen D, Wang M, Pham D, Sun S, Rao R, Singh R, et al. Hydrostatic mechanical stress regulates growth and maturation of the atrioventricular valve. Development. 2021;148: pubmed publisher
Mantri M, Scuderi G, Abedini Nassab R, Wang M, McKellar D, Shi H, et al. Spatiotemporal single-cell RNA sequencing of developing chicken hearts identifies interplay between cellular differentiation and morphogenesis. Nat Commun. 2021;12:1771 pubmed publisher
Mitsuhashi S, Nakagawa S, Sasaki Honda M, Sakurai H, Frith M, Mitsuhashi H. Nanopore direct RNA sequencing detects DUX4-activated repeats and isoforms in human muscle cells. Hum Mol Genet. 2021;30:552-563 pubmed publisher
Lamotte J, Roquevière S, Gautier H, Raban E, Bouré C, Fonfria E, et al. hiPSC-Derived Neurons Provide a Robust and Physiologically Relevant In Vitro Platform to Test Botulinum Neurotoxins. Front Pharmacol. 2020;11:617867 pubmed publisher
Endo Y, Baldino K, Li B, Zhang Y, Sakthivel D, MacArthur M, et al. Loss of ARNT in skeletal muscle limits muscle regeneration in aging. FASEB J. 2020;34:16086-16104 pubmed publisher
Ferre Fernández J, Sorokina E, Thompson S, Collery R, Nordquist E, Lincoln J, et al. Disruption of foxc1 genes in zebrafish results in dosage-dependent phenotypes overlapping Axenfeld-Rieger syndrome. Hum Mol Genet. 2020;29:2723-2735 pubmed publisher
Sato Y, Tate H, Yoshizawa F, Sato Y. Data on the proliferation and differentiation of C2C12 myoblast treated with branched-chain ketoacid dehydrogenase kinase inhibitor. Data Brief. 2020;31:105766 pubmed publisher
Testa G, Russo M, Di Benedetto G, Barbato M, Parisi S, Pirozzi F, et al. Bmi1 inhibitor PTC-209 promotes Chemically-induced Direct Cardiac Reprogramming of cardiac fibroblasts into cardiomyocytes. Sci Rep. 2020;10:7129 pubmed publisher
Taye N, Stanley S, Hubmacher D. Stable Knockdown of Genes Encoding Extracellular Matrix Proteins in the C2C12 Myoblast Cell Line Using Small-Hairpin (sh)RNA. J Vis Exp. 2020;: pubmed publisher
Hosoyama T. Possible application of muscle specific conditional mouse-derived induced pluripotent stem cells for muscle research. Biochem Biophys Rep. 2020;21:100744 pubmed publisher
Ono Y, Maejima Y, Saito M, Sakamoto K, Horita S, Shimomura K, et al. TAK-242, a specific inhibitor of Toll-like receptor 4 signalling, prevents endotoxemia-induced skeletal muscle wasting in mice. Sci Rep. 2020;10:694 pubmed publisher
Tokutake Y, Yamada K, Hayashi S, Arai W, Watanabe T, Yonekura S. IRE1-XBP1 Pathway of the Unfolded Protein Response Is Required during Early Differentiation of C2C12 Myoblasts. Int J Mol Sci. 2019;21: pubmed publisher
Grajcarek J, Monlong J, Nishinaka Arai Y, Nakamura M, Nagai M, Matsuo S, et al. Genome-wide microhomologies enable precise template-free editing of biologically relevant deletion mutations. Nat Commun. 2019;10:4856 pubmed publisher
Martínez Lagunas K, Yamaguchi Y, Becker C, Geisen C, DeRuiter M, Miura M, et al. In vivo detection of programmed cell death during mouse heart development. Cell Death Differ. 2020;27:1398-1414 pubmed publisher
Li S, Karri D, Sanchez Ortiz E, Jaichander P, Bassel Duby R, Liu N, et al. Sema3a-Nrp1 Signaling Mediates Fast-Twitch Myofiber Specificity of Tw2+ Cells. Dev Cell. 2019;51:89-98.e4 pubmed publisher
Islam R, Yoon H, Shin H, Bae H, Kim B, Yoon W, et al. Peptidyl-prolyl cis-trans isomerase NIMA interacting 1 regulates skeletal muscle fusion through structural modification of Smad3 in the linker region. J Cell Physiol. 2018;233:9390-9403 pubmed publisher
Tsuchiya M, Hara Y, Okuda M, Itoh K, Nishioka R, Shiomi A, et al. Cell surface flip-flop of phosphatidylserine is critical for PIEZO1-mediated myotube formation. Nat Commun. 2018;9:2049 pubmed publisher
Iyer P, Mavoungou L, Ronzoni F, Zemla J, Schmid Siegert E, Antonini S, et al. Autologous Cell Therapy Approach for Duchenne Muscular Dystrophy using PiggyBac Transposons and Mesoangioblasts. Mol Ther. 2018;26:1093-1108 pubmed publisher
Kudou K, Komatsu T, Nogami J, Maehara K, Harada A, Saeki H, et al. The requirement of Mettl3-promoted MyoD mRNA maintenance in proliferative myoblasts for skeletal muscle differentiation. Open Biol. 2017;7: pubmed publisher
Ono Y, Sakamoto K. Lipopolysaccharide inhibits myogenic differentiation of C2C12 myoblasts through the Toll-like receptor 4-nuclear factor-?B signaling pathway and myoblast-derived tumor necrosis factor-?. PLoS ONE. 2017;12:e0182040 pubmed publisher
Wang X, Huang N, Yang M, Wei D, Tai H, Han X, et al. FTO is required for myogenesis by positively regulating mTOR-PGC-1α pathway-mediated mitochondria biogenesis. Cell Death Dis. 2017;8:e2702 pubmed publisher
Fukuda R, Gunawan F, Beisaw A, Jiménez Amilburu V, Maischein H, Kostin S, et al. Proteolysis regulates cardiomyocyte maturation and tissue integration. Nat Commun. 2017;8:14495 pubmed publisher
Pumberger M, Qazi T, Ehrentraut M, Textor M, Kueper J, Stoltenburg Didinger G, et al. Synthetic niche to modulate regenerative potential of MSCs and enhance skeletal muscle regeneration. Biomaterials. 2016;99:95-108 pubmed publisher
Yao J, Wang X, Ren H, Liu G, Lu P. Ultrastructure of medial rectus muscles in patients with intermittent exotropia. Eye (Lond). 2016;30:146-51 pubmed publisher
Albini S, Coutinho Toto P, Dall Agnese A, Malecova B, Cenciarelli C, Felsani A, et al. Brahma is required for cell cycle arrest and late muscle gene expression during skeletal myogenesis. EMBO Rep. 2015;16:1037-50 pubmed publisher
Gibson T, Gersbach C. Single-molecule analysis of myocyte differentiation reveals bimodal lineage commitment. Integr Biol (Camb). 2015;7:663-71 pubmed publisher
Martinez Fernandez A, Nelson T, Reyes S, Alekseev A, Secreto F, Perez Terzic C, et al. iPS cell-derived cardiogenicity is hindered by sustained integration of reprogramming transgenes. Circ Cardiovasc Genet. 2014;7:667-76 pubmed publisher
Ifkovits J, Addis R, Epstein J, Gearhart J. Inhibition of TGF? signaling increases direct conversion of fibroblasts to induced cardiomyocytes. PLoS ONE. 2014;9:e89678 pubmed publisher
Addis R, Ifkovits J, Pinto F, Kellam L, Esteso P, Rentschler S, et al. Optimization of direct fibroblast reprogramming to cardiomyocytes using calcium activity as a functional measure of success. J Mol Cell Cardiol. 2013;60:97-106 pubmed publisher
Lee H, Bae G, Leem Y, Choi H, Kang T, Cho H, et al. Phosphorylation of Stim1 at serine 575 via netrin-2/Cdo-activated ERK1/2 is critical for the promyogenic function of Stim1. Mol Biol Cell. 2012;23:1376-87 pubmed publisher
Stadler G, Chen J, Wagner K, Robin J, Shay J, Emerson C, et al. Establishment of clonal myogenic cell lines from severely affected dystrophic muscles - CDK4 maintains the myogenic population. Skelet Muscle. 2011;1:12 pubmed publisher
Gerhart J, Neely C, Elder J, Pfautz J, Perlman J, Narciso L, et al. Cells that express MyoD mRNA in the epiblast are stably committed to the skeletal muscle lineage. J Cell Biol. 2007;178:649-60 pubmed
Wang Z, Wang D, Pipes G, Olson E. Myocardin is a master regulator of smooth muscle gene expression. Proc Natl Acad Sci U S A. 2003;100:7129-34 pubmed
Sellers J. Myosins: a diverse superfamily. Biochim Biophys Acta. 2000;1496:3-22 pubmed
Bader D, Masaki T, Fischman D. Immunochemical analysis of myosin heavy chain during avian myogenesis in vivo and in vitro. J Cell Biol. 1982;95:763-70 pubmed
product information
Product Type :
Antibody
Product Name :
Myosin 4 Monoclonal Antibody (MF20), eBioscience
Catalog # :
14-6503-82
Quantity :
100 µg
Price :
US 340.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Bovine, Canine, Chicken, Chimpanzee, Feline, Guinea Pig, Human, Mouse, Non-human primate, Rabbit, Rat
Applications :
Immunocytochemistry: 1:100-1:500, Western Blot: 1:500-1:1,000
Species :
Bovine, Canine, Chicken, Chimpanzee, Feline, Guinea Pig, Human, Mouse, Non-human primate, Rabbit, Rat
Clone :
MF20
Isotype :
IgG2b, kappa
Storage :
4° C
Description :
Target protein includes a fast myosin isoform expressed in skeletal muscle and has function involved in Muscle contraction.
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 1:100-1:500, Western Blot: 1:500-1:1,000
Aliases :
2B myosin heavy chain; AI506973; fast myosin heavy chain 2B; LOW QUALITY PROTEIN: myosin-4; MHC; MHC2B; Minimsc; Minmus; MM; MYH1; MYH2B; MYH-2B; myh4; MyHC IIb isoform; myHC-2b; MyHC-IIb; Myhsf; myosin heavy chain; myosin heavy chain 1; myosin heavy chain 2b; myosin heavy chain 2X; myosin heavy chain 4; Myosin heavy chain IIb; myosin heavy chain IIb isoform; myosin heavy chain isoform 2b; myosin heavy chain type IIb; Myosin heavy chain, skeletal muscle; myosin heavy chain, skeletal muscle, fetal; Myosin heavy chain, skeletal muscle, juvenile; myosin, heavy chain 4, skeletal muscle; myosin, heavy polypeptide 4, skeletal muscle; myosin-4; unnamed protein product
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA