This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
RIP3 Polyclonal Antibody, eBioscience™
catalog :
14-6048-82
quantity :
100 µg
price :
US 309.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
mouse, rat
application :
western blot, immunohistochemistry
product information
Product Type :
Antibody
Product Name :
RIP3 Polyclonal Antibody, eBioscience™
Catalog # :
14-6048-82
Quantity :
100 µg
Price :
US 309.00
Clonality :
Polyclonal
Purity :
Affinity chromatography
Host :
Rabbit
Reactivity :
Mouse, Rat
Applications :
Immunohistochemistry: Assay-Dependent, Western Blot: 0.5-4 µg/mL
Species :
Mouse, Rat
Isotype :
IgG
Storage :
4° C
Description :
RIP3 is a novel member of RIP Ser/Thr kinase family. It is a potent inducer of apoptosis and is an important component of TNFR1 signaling complex. RIP3 consists of an N-terminal RIP-like-Kinase domain and a unique, non-homologous C-terminus responsible for caspase activation and apoptosis induction. RIP3 is expressed in multiple tissues including hematopoietic cells and plays a functional role in the regulation of apoptosis and NF-kB signaling. It is recruited to the TNFR1 signaling complex in a RIP-dependant manner where it induces apoptosis by activating caspases and/or inhibiting TNFR1-induced NF-kB activation. RIP3 negatively regulates the TLR3-Trif-mediated NF-kB signaling pathway by competing with the binding of Trif to RIP1. The human RIP3 gene is localized in the chromosomal region 14q11.2.
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry: Assay-Dependent, Western Blot: 0.5-4 µg/mL
Aliases :
2610528K09Rik; AW107945; Hcyp2; Homocysteine respondent protein HCYP2; mRIP3; receptor interacting protein 3; receptor interacting serine/threonine kinase 3; receptor-interacting protein 3; receptor-interacting serine/threonine-protein kinase 3; receptor-interacting serine-threonine kinase 3; Rip3; RIP-3; Ripk3; RIP-like protein kinase 3
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA