Trop2 (EGP-1) Monoclonal Antibody (MR54), eBioscience | Invitrogen 14-6024-82 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Trop2 (EGP-1) Monoclonal Antibody (MR54), eBioscience

catalog :

14-6024-82

quantity :

100 ug

price :

US 366.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MR54

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

citations: 4

Reference
Bauderlique Le Roy H, Vennin C, Brocqueville G, Spruyt N, Adriaenssens E, Bourette R. Enrichment of Human Stem-Like Prostate Cells with s-SHIP Promoter Activity Uncovers a Role in Stemness for the Long Noncoding RNA H19. Stem Cells Dev. 2015;24:1252-62 pubmed publisher
Cubas R, Zhang S, Li M, Chen C, Yao Q. Trop2 expression contributes to tumor pathogenesis by activating the ERK MAPK pathway. Mol Cancer. 2010;9:253 pubmed publisher
Ripani E, Sacchetti A, Corda D, Alberti S. Human Trop-2 is a tumor-associated calcium signal transducer. Int J Cancer. 1998;76:671-6 pubmed
Stein R, Basu A, Goldenberg D, Lloyd K, Mattes M. Characterization of cluster 13: the epithelial/carcinoma antigen recognized by MAb RS7. Int J Cancer Suppl. 1994;8:98-102 pubmed

product information

Product Type :

Antibody

Product Name :

Trop2 (EGP-1) Monoclonal Antibody (MR54), eBioscience

Catalog # :

14-6024-82

Quantity :

100 ug

Price :

US 366.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: Assay-Dependent, Flow Cytometry: Assay-Dependent, Immunocytochemistry: 5 ug/mL, Immunohistochemistry (Paraffin): 5 ug/mL, Immunoprecipitation: Assay-Dependent, Western Blot: Assay-Dependent

Species :

Human

Clone :

MR54

Isotype :

IgG2a, kappa

Storage :

4 C

Description :

TROP2 is a carcinoma-associated antigen defined by the monoclonal antibody GA733. This antigen is a member of a family including at least two type I membrane proteins. It transduces an intracellular calcium signal and acts as a cell surface receptor. Mutations of its gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-Dependent, Flow Cytometry: Assay-Dependent, Immunocytochemistry: 5 ug/mL, Immunohistochemistry (Paraffin): 5 ug/mL, Immunoprecipitation: Assay-Dependent, Western Blot: Assay-Dependent

Aliases :

40kD glycoprotein, identified by monoclonal antibody GA733; C80403; cell surface glycoprotein TROP2; cell surface glycoprotein Trop-2; EGP1; EGP-1; epithelial glycoprotein-1; GA733; GA7331; GA733-1; gastrointestinal tumor-associated antigen GA7331; GP50; Ly97; lymphocyte antigen 97; M1S1; Membrane component chromosome 1 surface marker 1; membrane component, chromosome 1, surface marker 1; pancreatic carcinoma marker protein GA7331; pancreatic carcinoma marker protein GA733-1; parturition-related protein 1; Prp1; TACD2; TACSTD2; Trop2; truncated TACSTD2; tumor-associated calcium signal transducer 2; tunor-associated calcium signal transducer 2