CD272 (BTLA) Monoclonal Antibody (6G3), eBioscience | Invitrogen 14-5955-82 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD272 (BTLA) Monoclonal Antibody (6G3), eBioscience

catalog :

14-5955-82

quantity :

100 ug

price :

US 345.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6G3

reactivity :

mouse

application :

flow cytometry

citations: 3

Reference
Hurchla M, Sedy J, Gavrieli M, Gavrielli M, Drake C, Murphy T, et al. B and T lymphocyte attenuator exhibits structural and expression polymorphisms and is highly Induced in anergic CD4+ T cells. J Immunol. 2005;174:3377-85 pubmed
Sedy J, Gavrieli M, Potter K, Hurchla M, Lindsley R, Hildner K, et al. B and T lymphocyte attenuator regulates T cell activation through interaction with herpesvirus entry mediator. Nat Immunol. 2005;6:90-8 pubmed
Watanabe N, Gavrieli M, Sedy J, Yang J, Fallarino F, Loftin S, et al. BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1. Nat Immunol. 2003;4:670-9 pubmed

product information

Product Type :

Antibody

Product Name :

CD272 (BTLA) Monoclonal Antibody (6G3), eBioscience

Catalog # :

14-5955-82

Quantity :

100 ug

Price :

US 345.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.25 ug/test

Species :

Mouse

Clone :

6G3

Isotype :

IgG1, kappa

Storage :

4 C

Description :

BTLA or B and T-lymphocyte attenuator is a member of the co-inhibitory receptors of the CD28 superfamily. BTLA is a lymphocyte inhibitory receptor which inhibits lymphocytes during immunes responses. BTLA is constitutively expressed on most CD4+ and CD8+ T cells and its expression progressively decreases upon T cell activation. It remains expressed on Th1 cells, but not Th2 cells. BTLA is a unique co-receptor that interacts with the tumor necrosis factor receptor superfamily member herpesvirus entry mediator (HVEM). This interation is an important pathway regulating lymphocyte activation and/or homeostasis in the immune response.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.25 ug/test

Aliases :

A630002H24; B and T lymphocyte associated; B and T lymphocyte associated protein; B and T lymphocyte attenuator; B- and T-lymphocyte attenuator; B- and T-lymphocyte-associated protein; BTLA; BTLA_HUMAN; BTLA1; CD272; CD272 antigen; FLJ16065; MGC129743