SOX10 Monoclonal Antibody (20B7), eBioscience | Invitrogen 14-5923-82 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SOX10 Monoclonal Antibody (20B7), eBioscience

catalog :

14-5923-82

quantity :

100 ug

price :

US 471.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

20B7

The same clone is also sold as:

R&D Systems: NL2864R, MAB2864

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 4

Reference
Leopardo N, Vitullo A. Early embryonic development and spatiotemporal localization of mammalian primordial germ cell-associated proteins in the basal rodent Lagostomus maximus. Sci Rep. 2017;7:594 pubmed publisher
Ferletta M, Uhrbom L, Olofsson T, Ponten F, Westermark B. Sox10 has a broad expression pattern in gliomas and enhances platelet-derived growth factor-B--induced gliomagenesis. Mol Cancer Res. 2007;5:891-7 pubmed
Kim J, Lo L, Dormand E, Anderson D. SOX10 maintains multipotency and inhibits neuronal differentiation of neural crest stem cells. Neuron. 2003;38:17-31 pubmed
Lo L, Dormand E, Greenwood A, Anderson D. Comparison of the generic neuronal differentiation and neuron subtype specification functions of mammalian achaete-scute and atonal homologs in cultured neural progenitor cells. Development. 2002;129:1553-67 pubmed

product information

Product Type :

Antibody

Product Name :

SOX10 Monoclonal Antibody (20B7), eBioscience

Catalog # :

14-5923-82

Quantity :

100 ug

Price :

US 471.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 5 - 10 ug/mL, Immunohistochemistry (Frozen): 10 ug/mL, Immunohistochemistry (Paraffin): 10 ug/mL, Western Blot: 1 ug/ml

Species :

Human, Mouse, Rat

Clone :

20B7

Isotype :

IgG1, kappa

Storage :

4 C

Description :

SOX10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. This protein may act as a transcriptional activator after forming a protein complex with other proteins. It acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 5 - 10 ug/mL, Immunohistochemistry (Frozen): 10 ug/mL, Immunohistochemistry (Paraffin): 10 ug/mL, Western Blot: 1 ug/ml

Aliases :

cls; cls/sox10; colorless; colourless; colourless/sox10; DOM; dominant megacolon; dominant megacolon, mouse, human homolog of; golas; gos; HMG-box transcription factor Sox10; MGC15649; PCWH; Protein SOX-21; SOX10; Sox-10; sox10 protein; sox10b; Sox21; SOX9; SRY; SRY (sex determining region Y)-box 10; SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal); SRY box 10; SRY-box 10; SRY-box containing gene 10; SRY-box containing protein 10; SRY-box transcription factor 10; SRY-related HMG-box gene 10; transcription factor SOX-10; Transcription factor SOX-M; WS2E; WS4; WS4C; zgc:100757