This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD314 (NKG2D) Monoclonal Antibody (5C6), eBioscience
catalog :
14-5879-82
quantity :
100 ug
price :
US 261.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
5C6

The same clone is also sold as:
reactivity :
human
application :
immunohistochemistry, neutralization, immunoprecipitation, flow cytometry
citations: 4
Reference
Lim S, Kim T, Lee J, Sonn C, Kim K, Kim J, et al. Ex vivo expansion of highly cytotoxic human NK cells by cocultivation with irradiated tumor cells for adoptive immunotherapy. Cancer Res. 2013;73:2598-607 pubmed publisher
Seiler M, Brabcova I, Viklicky O, Hribova P, Rosenberger C, Pratschke J, et al. Heightened expression of the cytotoxicity receptor NKG2D correlates with acute and chronic nephropathy after kidney transplantation. Am J Transplant. 2007;7:423-33 pubmed
Bauer S, Groh V, Wu J, Steinle A, Phillips J, Lanier L, et al. Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. Science. 1999;285:727-9 pubmed
Groh V, Steinle A, Bauer S, Spies T. Recognition of stress-induced MHC molecules by intestinal epithelial gammadelta T cells. Science. 1998;279:1737-40 pubmed
product information
Product Type :
Antibody
Product Name :
CD314 (NKG2D) Monoclonal Antibody (5C6), eBioscience
Catalog # :
14-5879-82
Quantity :
100 ug
Price :
US 261.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 0.5 ug/test, Functional Assay: Assay-Dependent, Immunohistochemistry: Assay-Dependent, Immunoprecipitation: Assay-Dependent, Neutralization: Assay-Dependent
Species :
Human
Clone :
5C6
Isotype :
IgG2a
Storage :
4 C
Description :
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. NK cells can regulate specific humoral and cell-mediated immunity, and preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The NK gene encodes a member of the NKG2 family, and the encoded transmembrane protein is characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.5 ug/test, Functional Assay: Assay-Dependent, Immunohistochemistry: Assay-Dependent, Immunoprecipitation: Assay-Dependent, Neutralization: Assay-Dependent
Aliases :
CD314; D12S2489E; D6H12S2489E; killer cell lectin like receptor K1; Killer cell lectin-like receptor subfamily K member 1; killer cell lectin-like receptor subfamily K, member 1; KLR; Klrk1; natural killer cell group 2D; natural killer cell receptor; NK cell receptor D; NK lectin-like receptor; Nkg2d; NKG2-D; NKG2-D type II integral membrane protein; NKG2-D-activating NK receptor; NKLLR; Nkrp2; NKR-P2; NKR-P2, ortholog of human NKG2D
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA