CD357 (AITR/GITR) Monoclonal Antibody (eBioAITR), eBioscience™ | Invitrogen 14-5875-80 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD357 (AITR/GITR) Monoclonal Antibody (eBioAITR), eBioscience™

catalog :

14-5875-80

quantity :

25µg

price :

US 109

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

eBioAITR

reactivity :

human

application :

western blot, ELISA, flow cytometry

more info or order :

Invitrogen product webpage

citations: 12

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig s3a	Williams P, Basu S, Garcia Manero G, Hourigan C, Oetjen K, Cortes J, et al. The distribution of T-cell subsets and the expression of immune checkpoint receptors and ligands in patients with newly diagnosed and relapsed acute myeloid leukemia. Cancer. 2019;125:1470-1481 pubmed publisher
flow cytometry; human; loading ...; fig 6a	Komdeur F, Wouters M, Workel H, Tijans A, Terwindt A, Brunekreeft K, et al. CD103+ intraepithelial T cells in high-grade serous ovarian cancer are phenotypically diverse TCRÎ±Î²+ CD8Î±Î²+ T cells that can be targeted for cancer immunotherapy. Oncotarget. 2016;7:75130-75144 pubmed publisher
flow cytometry; human; loading ...; fig 3b	Kobayashi S, Watanabe T, Suzuki R, Furu M, Ito H, Ito J, et al. TGF-Î² induces the differentiation of human CXCL13-producing CD4(+) T cells. Eur J Immunol. 2016;46:360-71 pubmed publisher
	Miles B, Miller S, Folkvord J, Levy D, Rakasz E, Skinner P, et al. Follicular Regulatory CD8 T Cells Impair the Germinal Center Response in SIV and Ex Vivo HIV Infection. PLoS Pathog. 2016;12:e1005924 pubmed publisher
	Liu X, Gao N, Li M, Xu D, Hou Y, Wang Q, et al. Elevated levels of CD4(+)CD25(+)FoxP3(+) T cells in systemic sclerosis patients contribute to the secretion of IL-17 and immunosuppression dysfunction. PLoS ONE. 2013;8:e64531 pubmed publisher
	Satou Y, Utsunomiya A, Tanabe J, Nakagawa M, Nosaka K, Matsuoka M. HTLV-1 modulates the frequency and phenotype of FoxP3+CD4+ T cells in virus-infected individuals. Retrovirology. 2012;9:46 pubmed publisher
	Peng R, Huang Z, Zhang Y, Yuan Z, Xia Y, Jiang W, et al. Circulating and tumor-infiltrating Foxp3⁺ regulatory T cell subset in Chinese patients with extranodal NK/T cell lymphoma. Int J Biol Sci. 2011;7:1027-36 pubmed
	Yamagiwa T, Fukunishi S, Tachibana T, Okamura H, Yoshiya S, Kashiwamura S. Abrogation of Treg function deteriorates rheumatoid arthritis. Mod Rheumatol. 2012;22:80-8 pubmed publisher
	Lechner M, Megiel C, Russell S, Bingham B, Arger N, Woo T, et al. Functional characterization of human Cd33+ and Cd11b+ myeloid-derived suppressor cell subsets induced from peripheral blood mononuclear cells co-cultured with a diverse set of human tumor cell lines. J Transl Med. 2011;9:90 pubmed publisher
	Green A, Mattila J, Bigbee C, Bongers K, Lin P, Flynn J. CD4(+) regulatory T cells in a cynomolgus macaque model of Mycobacterium tuberculosis infection. J Infect Dis. 2010;202:533-41 pubmed publisher
	Nagata S, Ise T, Pastan I. Fc receptor-like 3 protein expressed on IL-2 nonresponsive subset of human regulatory T cells. J Immunol. 2009;182:7518-26 pubmed publisher
	Horlock C, Stott B, Dyson P, Morishita M, Coombes R, Savage P, et al. The effects of trastuzumab on the CD4+CD25+FoxP3+ and CD4+IL17A+ T-cell axis in patients with breast cancer. Br J Cancer. 2009;100:1061-7 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD357 (AITR/GITR) Monoclonal Antibody (eBioAITR), eBioscience™

Catalog # :

14-5875-80

Quantity :

25µg

Price :

US 109

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: Assay-Dependent, Flow Cytometry: 0.125 µg/test, Western Blot: Assay-Dependent

Species :

Human

Clone :

eBioAITR

Isotype :

IgG1, kappa

Storage :

4° C

Description :

Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also called GITR or AITR is a protein that in humans is encoded by the TNFRSF18 gene. It is mapped to 1p36.33. This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+)CD4 (+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-Dependent, Flow Cytometry: 0.125 µg/test, Western Blot: Assay-Dependent

Aliases :

Activation-inducible TNFR family receptor; AITR; CD357; GITR; GITR-D; Glucocorticoid-induced TNFR-related protein; PRO364; TNF receptor superfamily activation-inducible protein; TNF receptor superfamily member 18; TNFRSF18; Tumor necrosis factor receptor superfamily member 18; tumor necrosis factor receptor superfamily, member 18; UNQ319; UNQ319/PRO364

more info or order :

Invitrogen product webpage