CD357 (AITR/GITR) Monoclonal Antibody (eBioAITR), eBioscience™ | Invitrogen 14-5875-37 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD357 (AITR/GITR) Monoclonal Antibody (eBioAITR), eBioscience™

catalog :

14-5875-37

quantity :

2 mg

price :

1200.00 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

eBioAITR

reactivity :

human

application :

western blot, ELISA, flow cytometry

more info or order :

Invitrogen product webpage

citations: 4

Reference
Miles B, Miller S, Folkvord J, Levy D, Rakasz E, Skinner P, et al. Follicular Regulatory CD8 T Cells Impair the Germinal Center Response in SIV and Ex Vivo HIV Infection. PLoS Pathog. 2016;12:e1005924 pubmed publisher
Komdeur F, Wouters M, Workel H, Tijans A, Terwindt A, Brunekreeft K, et al. CD103+ intraepithelial T cells in high-grade serous ovarian cancer are phenotypically diverse TCRÎ±Î²+ CD8Î±Î²+ T cells that can be targeted for cancer immunotherapy. Oncotarget. 2016;7:75130-75144 pubmed publisher
Satou Y, Utsunomiya A, Tanabe J, Nakagawa M, Nosaka K, Matsuoka M. HTLV-1 modulates the frequency and phenotype of FoxP3+CD4+ T cells in virus-infected individuals. Retrovirology. 2012;9:46 pubmed publisher
Green A, Mattila J, Bigbee C, Bongers K, Lin P, Flynn J. CD4(+) regulatory T cells in a cynomolgus macaque model of Mycobacterium tuberculosis infection. J Infect Dis. 2010;202:533-41 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD357 (AITR/GITR) Monoclonal Antibody (eBioAITR), eBioscience™

Catalog # :

14-5875-37

Quantity :

2 mg

Price (USD) :

1200.00 USD

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: Assay-Dependent, Flow Cytometry: 0.125 µg/test, Western Blot: Assay-Dependent

Species :

Human

Clone :

eBioAITR

Isotype :

IgG1, kappa

Storage :

4° C

Description :

Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also called GITR or AITR is a protein that in humans is encoded by the TNFRSF18 gene. It is mapped to 1p36.33. This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+)CD4 (+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-Dependent, Flow Cytometry: 0.125 µg/test, Western Blot: Assay-Dependent

Aliases :

Activation-inducible TNFR family receptor; AITR; CD357; Gitr; GITR-D; glucocorticoid-induced TNFR-related protein; PRO364; TNF receptor superfamily activation-inducible protein; TNF receptor superfamily member 18; Tnfrsf18; Tumor necrosis factor receptor superfamily member 18; tumor necrosis factor receptor superfamily, member 18; UNQ319; UNQ319/PRO364

more info or order :

Invitrogen product webpage