Integrin beta 7 Monoclonal Antibody (FIB504), eBioscience | Invitrogen 14-5867-37 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Integrin beta 7 Monoclonal Antibody (FIB504), eBioscience

catalog :

14-5867-37

quantity :

2 mg

price :

US 1474.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

FIB504

The same clone is also sold as:

BioLegend: 321248, 321227, 321241, 321244, 321246, 321213, 321212, 321221, 321208, 321222, 321243, 321240, 321249, 321229, 321203, 321250, 321214, 321207, 321247, 321202, 321204, 321220, 321236, 321209, 321226, 321234, 321231, 321237, 321238, 321235, 321223, 321239, 321233, 321225, 321242, 321219, 321245, 321224
Santa Cruz Biotechnology: sc-23919 AC, sc-23919 L, sc-23919 HRP, sc-23919
BD Biosciences: 555945, 551059
ichorbio: ICH1108, ICH1034
Bio X Cell: BE0062-50MG, BE0062-5MG, BE0062-1MG, BE0062-100MG, BE0062-25MG
Abcam: ab95816

reactivity :

human, mouse

application :

flow cytometry

citations: 3

Reference
Alhaj Hussen K, Chabaane E, Nelson E, Lekiashvili S, Diop S, Keita S, et al. Multimodal cartography of human lymphopoiesis reveals B and T/NK/ILC lineages are subjected to differential regulation. iScience. 2023;26:107890 pubmed publisher
Buscher K, Wang H, Zhang X, Striewski P, Wirth B, Saggu G, et al. Protection from septic peritonitis by rapid neutrophil recruitment through omental high endothelial venules. Nat Commun. 2016;7:10828 pubmed publisher
Hovhannisyan Z, Treatman J, Littman D, Mayer L. Characterization of interleukin-17-producing regulatory T cells in inflamed intestinal mucosa from patients with inflammatory bowel diseases. Gastroenterology. 2011;140:957-65 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Integrin beta 7 Monoclonal Antibody (FIB504), eBioscience

Catalog # :

14-5867-37

Quantity :

2 mg

Price :

US 1474.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Human, Mouse

Applications :

Flow Cytometry: 0.125 ug/test, Functional Assay: Assay-Dependent

Species :

Human, Mouse

Clone :

FIB504

Isotype :

IgG2a, kappa

Storage :

4 C

Description :

Integrin beta 7 associates with integrin alpha 4 (CD49d) to form the alpha 4 beta 7 integrin LPAM-1, expressed on intraepithelial lymphocytes. It also associates with alpha E (CD103) to form the alpha E beta 7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Ligands for LPAM-1 include VCAM-1 (CD106), MAdCAM-1 and fibronectin, while the ligand of HML-1 is E-cadherin (CD324). Integrin beta 7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.125 ug/test, Functional Assay: Assay-Dependent

Aliases :

Gut homing receptor beta subunit; integrin beta 7; integrin beta 7 subunit; integrin beta-7; Integrin beta-P; integrin subunit beta 7; integrin, beta 7; ITGB7; Ly69; M290 IEL antigen