product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Endomucin Monoclonal Antibody (eBioV.7C7 (V.7C7)), eBioscience
catalog :
14-5851-85
quantity :
500 µg
price :
US 263
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
eBioV.7C7 (V.7C7)
reactivity :
mouse
application :
western blot, immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 41
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:100; loading ...; fig 9a
Quijada P, Trembley M, Misra A, Myers J, Baker C, Pérez Hernández M, et al. Coordination of endothelial cell positioning and fate specification by the epicardium. Nat Commun. 2021;12:4155 pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig 7d
Maruyama K, Naemura K, Arima Y, Uchijima Y, Nagao H, Yoshihara K, et al. Semaphorin3E-PlexinD1 signaling in coronary artery and lymphatic vessel development with clinical implications in myocardial recovery. iScience. 2021;24:102305 pubmed publisher
  • immunohistochemistry; mouse; 1:400; fig 1c
Hosaka K, Yang Y, Seki T, Fischer C, Dubey O, Fredlund E, et al. Pericyte-fibroblast transition promotes tumor growth and metastasis. Proc Natl Acad Sci U S A. 2016;113:E5618-27 pubmed publisher
  • immunohistochemistry; mouse; 1:150; fig 4
Sun H, Zhang X, Zhao L, Zhen X, Huang S, Wang S, et al. Attenuation of atherosclerotic lesions in diabetic apolipoprotein E-deficient mice using gene silencing of macrophage migration inhibitory factor. J Cell Mol Med. 2015;19:836-49 pubmed publisher
Jia W, Kong L, Kidoya H, Naito H, Muramatsu F, Hayashi Y, et al. Indispensable role of Galectin-3 in promoting quiescence of hematopoietic stem cells. Nat Commun. 2021;12:2118 pubmed publisher
Cha B, Ho Y, Geng X, Mahamud M, Chen L, Kim Y, et al. YAP and TAZ maintain PROX1 expression in the developing lymphatic and lymphovenous valves in response to VEGF-C signaling. Development. 2020;147: pubmed publisher
Gillich A, Zhang F, Farmer C, Travaglini K, Tan S, Gu M, et al. Capillary cell-type specialization in the alveolus. Nature. 2020;586:785-789 pubmed publisher
Nandadasa S, Szafron J, Pathak V, Murtada S, Kraft C, O Donnell A, et al. Vascular dimorphism ensured by regulated proteoglycan dynamics favors rapid umbilical artery closure at birth. elife. 2020;9: pubmed publisher
Pflügler S, Svinka J, Scharf I, Crncec I, Filipits M, Charoentong P, et al. IDO1+ Paneth cells promote immune escape of colorectal cancer. Commun Biol. 2020;3:252 pubmed publisher
Lu Z, Dmitriev I, Brough D, Kashentseva E, Li J, Curiel D. A New Gorilla Adenoviral Vector with Natural Lung Tropism Avoids Liver Toxicity and Is Amenable to Capsid Engineering and Vector Retargeting. J Virol. 2020;94: pubmed publisher
Jiang H, Zhang L, Liu X, Sun W, Kato K, Chen C, et al. Angiocrine FSTL1 (Follistatin-Like Protein 1) Insufficiency Leads to Atrial and Venous Wall Fibrosis via SMAD3 Activation. Arterioscler Thromb Vasc Biol. 2020;40:958-972 pubmed publisher
Vila Ellis L, Cain M, Hutchison V, Flodby P, Crandall E, Borok Z, et al. Epithelial Vegfa Specifies a Distinct Endothelial Population in the Mouse Lung. Dev Cell. 2020;52:617-630.e6 pubmed publisher
Dumas S, Meta E, Borri M, Goveia J, Rohlenova K, Conchinha N, et al. Single-Cell RNA Sequencing Reveals Renal Endothelium Heterogeneity and Metabolic Adaptation to Water Deprivation. J Am Soc Nephrol. 2020;31:118-138 pubmed publisher
Unterleuthner D, Neuhold P, Schwarz K, Janker L, Neuditschko B, Nivarthi H, et al. Cancer-associated fibroblast-derived WNT2 increases tumor angiogenesis in colon cancer. Angiogenesis. 2020;23:159-177 pubmed publisher
Ji G, Xu R, Niu Y, Li N, Ivashkiv L, Bostrom M, et al. Vascular endothelial growth factor pathway promotes osseointegration and CD31hiEMCNhi endothelium expansion in a mouse tibial implant model: an animal study. Bone Joint J. 2019;101-B:108-114 pubmed publisher
Oz Levi D, Olender T, Bar Joseph I, Zhu Y, Marek Yagel D, Barozzi I, et al. Noncoding deletions reveal a gene that is critical for intestinal function. Nature. 2019;: pubmed publisher
Frisch B, Hoffman C, Latchney S, Lamere M, Myers J, Ashton J, et al. Aged marrow macrophages expand platelet-biased hematopoietic stem cells via Interleukin1B. JCI Insight. 2019;5: pubmed publisher
Wang B, Kaufmann B, Engleitner T, Lu M, Mogler C, Olsavszky V, et al. Brg1 promotes liver regeneration after partial hepatectomy via regulation of cell cycle. Sci Rep. 2019;9:2320 pubmed publisher
Xu R, Yallowitz A, Qin A, Wu Z, Shin D, Kim J, et al. Targeting skeletal endothelium to ameliorate bone loss. Nat Med. 2018;24:823-833 pubmed publisher
Rohr Udilova N, Bauer E, Timelthaler G, Eferl R, Stolze K, Pinter M, et al. Impact of glutathione peroxidase 4 on cell proliferation, angiogenesis and cytokine production in hepatocellular carcinoma. Oncotarget. 2018;9:10054-10068 pubmed publisher
Crncec I, Modak M, Gordziel C, Svinka J, Scharf I, Moritsch S, et al. STAT1 is a sex-specific tumor suppressor in colitis-associated colorectal cancer. Mol Oncol. 2018;12:514-528 pubmed publisher
Xiang F, Fang M, Yutzey K. Loss of ?-catenin in resident cardiac fibroblasts attenuates fibrosis induced by pressure overload in mice. Nat Commun. 2017;8:712 pubmed publisher
Sun J, Sun B, Sun R, Zhu D, Zhao X, Zhang Y, et al. HMGA2 promotes vasculogenic mimicry and tumor aggressiveness by upregulating Twist1 in gastric carcinoma. Sci Rep. 2017;7:2229 pubmed publisher
Yang X, Sui W, Dong M, Lim S, Seki T, Guo Z, et al. Switching harmful visceral fat to beneficial energy combustion improves metabolic dysfunctions. JCI Insight. 2017;2:e89044 pubmed publisher
Daniels B, Jujjavarapu H, Durrant D, Williams J, Green R, White J, et al. Regional astrocyte IFN signaling restricts pathogenesis during neurotropic viral infection. J Clin Invest. 2017;127:843-856 pubmed publisher
Martino V, Sabljic T, Deschamps P, Green R, Akula M, Peacock E, et al. Conditional deletion of AP-2? in mouse cranial neural crest results in anterior segment dysgenesis and early-onset glaucoma. Dis Model Mech. 2016;9:849-61 pubmed publisher
Lim S, Hosaka K, Nakamura M, Cao Y. Co-option of pre-existing vascular beds in adipose tissue controls tumor growth rates and angiogenesis. Oncotarget. 2016;7:38282-38291 pubmed publisher
Wirrig E, Gomez M, Hinton R, Yutzey K. COX2 inhibition reduces aortic valve calcification in vivo. Arterioscler Thromb Vasc Biol. 2015;35:938-47 pubmed publisher
Lim S, Zhang Y, Zhang D, Chen F, Hosaka K, Feng N, et al. VEGFR2-mediated vascular dilation as a mechanism of VEGF-induced anemia and bone marrow cell mobilization. Cell Rep. 2014;9:569-80 pubmed publisher
Lu Z, Kaliberov S, Zhang J, Muz B, Azab A, Sohn R, et al. The myeloid-binding peptide adenoviral vector enables multi-organ vascular endothelial gene targeting. Lab Invest. 2014;94:881-92 pubmed publisher
Prahst C, Kasaai B, Moraes F, Jahnsen E, Larrivee B, Villegas D, et al. The H2.0-like homeobox transcription factor modulates yolk sac vascular remodeling in mouse embryos. Arterioscler Thromb Vasc Biol. 2014;34:1468-76 pubmed publisher
Lu Z, Kaliberov S, Sohn R, Kaliberova L, Curiel D, Arbeit J. Transcriptional targeting of primary and metastatic tumor neovasculature by an adenoviral type 5 roundabout4 vector in mice. PLoS ONE. 2013;8:e83933 pubmed publisher
Geng Y, Li L, Dong Y, Liu X, Li X, Ning W. Impaired elastin deposition in Fstl1-/- lung allograft under the renal capsule. PLoS ONE. 2013;8:e81368 pubmed publisher
Tan X, Carretero J, Chen Z, Zhang J, Wang Y, Chen J, et al. Loss of p53 attenuates the contribution of IL-6 deletion on suppressed tumor progression and extended survival in Kras-driven murine lung cancer. PLoS ONE. 2013;8:e80885 pubmed publisher
Hosaka K, Yang Y, Seki T, Nakamura M, Andersson P, Rouhi P, et al. Tumour PDGF-BB expression levels determine dual effects of anti-PDGF drugs on vascular remodelling and metastasis. Nat Commun. 2013;4:2129 pubmed publisher
Gay L, Miller M, Ventura P, Devasthali V, Vue Z, Thompson H, et al. Mouse TU tagging: a chemical/genetic intersectional method for purifying cell type-specific nascent RNA. Genes Dev. 2013;27:98-115 pubmed publisher
Zhang Q, He X, Chen L, Zhang C, Gao X, Yang Z, et al. Synergistic regulation of p53 by Mdm2 and Mdm4 is critical in cardiac endocardial cushion morphogenesis during heart development. J Pathol. 2012;228:416-28 pubmed publisher
Schachterle W, Rojas A, Xu S, Black B. ETS-dependent regulation of a distal Gata4 cardiac enhancer. Dev Biol. 2012;361:439-49 pubmed publisher
Feng Q, Di R, Tao F, Chang Z, Lu S, Fan W, et al. PDK1 regulates vascular remodeling and promotes epithelial-mesenchymal transition in cardiac development. Mol Cell Biol. 2010;30:3711-21 pubmed publisher
Matsubara A, Iwama A, Yamazaki S, Furuta C, Hirasawa R, Morita Y, et al. Endomucin, a CD34-like sialomucin, marks hematopoietic stem cells throughout development. J Exp Med. 2005;202:1483-92 pubmed
Morgan S, Samulowitz U, Darley L, Simmons D, Vestweber D. Biochemical characterization and molecular cloning of a novel endothelial-specific sialomucin. Blood. 1999;93:165-75 pubmed
product information
Product Type :
Antibody
Product Name :
Endomucin Monoclonal Antibody (eBioV.7C7 (V.7C7)), eBioscience
Catalog # :
14-5851-85
Quantity :
500 µg
Price :
US 263
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 1 µg/test, Immunohistochemistry (Paraffin): Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: 1:1,000
Species :
Mouse
Clone :
eBioV.7C7 (V.7C7)
Isotype :
IgG2a, kappa
Storage :
4° C
Description :
Endomucin (EMCN) also known as endothelial sialomucin or mucin-like sialoglycoprotein interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1 µg/test, Immunohistochemistry (Paraffin): Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: 1:1,000
Aliases :
0610012K22Rik; AI315669; Emcn; EMCN2; Endomucin; endomucin-1; endomucin-1/2; Endomucin-2; gastric cancer antigen Ga34; Muc14; MUC-14; mucin 14, endothelial; mucin-14; sialomucin
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA