Embigin Monoclonal Antibody (G7.43.1), eBioscience | Invitrogen 14-5839-85 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Embigin Monoclonal Antibody (G7.43.1), eBioscience

catalog :

14-5839-85

quantity :

500 ug

price :

US 420.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

G7.43.1

reactivity :

mouse

application :

immunohistochemistry, flow cytometry, immunohistochemistry - frozen section

citations: 5

Reference
Talvi S, Jokinen J, Sipil xe4 K, Rappu P, Zhang F, Poutanen M, et al. Embigin deficiency leads to delayed embryonic lung development and high neonatal mortality in mice. iScience. 2024;27:108914 pubmed publisher
Newton S, Aguilar C, Bunton Stasyshyn R, Flook M, Stewart M, Marcotti W, et al. Absence of Embigin accelerates hearing loss and causes sub-viability, brain and heart defects in C57BL/6N mice due to interaction with Cdh23ahl. iScience. 2023;26:108056 pubmed publisher
Severe N, Karabacak N, Gustafsson K, Baryawno N, Courties G, Kfoury Y, et al. Stress-Induced Changes in Bone Marrow Stromal Cell Populations Revealed through Single-Cell Protein Expression Mapping. Cell Stem Cell. 2019;25:570-583.e7 pubmed publisher
Pridans C, Holmes M, Polli M, Wettenhall J, Dakic A, Corcoran L, et al. Identification of Pax5 target genes in early B cell differentiation. J Immunol. 2008;180:1719-28 pubmed
Huang R, Ozawa M, Kadomatsu K, Muramatsu T. Embigin, a member of the immunoglobulin superfamily expressed in embryonic cells, enhances cell-substratum adhesion. Dev Biol. 1993;155:307-14 pubmed

product information

Product Type :

Antibody

Product Name :

Embigin Monoclonal Antibody (G7.43.1), eBioscience

Catalog # :

14-5839-85

Quantity :

500 ug

Price :

US 420.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.25 ug/test, Immunohistochemistry (Frozen): Assay-Dependent

Species :

Mouse

Clone :

G7.43.1

Isotype :

IgG2b, kappa

Storage :

4 C

Description :

Embigin is a 327 amino acid regulatory protein belonging to the immunoglobulin superfamily class of CAMs, and has two Ig-like (immunoglobulin-like) V- type domains. In situ hybridization analysis shows that Embigin has specific carbohydrate epitopes and plays an important role in early postimplantation embryogenesis. A highly glycosylated transmembrane glycoprotein, Embigin acts as a regulator of cell/ECM interactions during development and homeostasis of normal adult tissues. Transfection studies suggest its role in promotion of integrin-mediated cell-substratum adhesion. Widely expressed in most of the tissues and embryonal carcinoma cells, prostate and mammary cancer cell lines, it may also help in the classification of human carcinomas.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.25 ug/test, Immunohistochemistry (Frozen): Assay-Dependent

Aliases :

AL022799; EMB; Embigin; embigin homolog; glycoprotein 70; Gp70; Teratocarcinoma glycoprotein Gp-70