Published Application/Species/Sample/Dilution | Reference |
---|
- flow cytometry; mouse; loading ...; fig 2k
| Leone R, Zhao L, Englert J, Sun I, Oh M, Sun I, et al. Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion. Science. 2019;366:1013-1021 pubmed publisher
|
- flow cytometry; mouse; loading ...; fig s5a
| Kawalkowska J, Ogbechi J, Venables P, Williams R. cIAP1/2 inhibition synergizes with TNF inhibition in autoimmunity by down-regulating IL-17A and inducing Tregs. Sci Adv. 2019;5:eaaw5422 pubmed publisher
|
- flow cytometry; human; loading ...; fig 1b
| Remmerswaal E, Hombrink P, Nota B, Pircher H, ten Berge I, van Lier R, et al. Expression of IL-7Rα and KLRG1 defines functionally distinct CD8+ T-cell populations in humans. Eur J Immunol. 2019;49:694-708 pubmed publisher
|
- flow cytometry; mouse; loading ...; fig 2d, 4g
| Karmaus P, Chen X, Lim S, Herrada A, Nguyen T, Xu B, et al. Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity. Nature. 2019;565:101-105 pubmed publisher
|
- flow cytometry; mouse; loading ...; fig 7c
| Li F, Zeng Z, Xing S, Gullicksrud J, Shan Q, Choi J, et al. Ezh2 programs TFH differentiation by integrating phosphorylation-dependent activation of Bcl6 and polycomb-dependent repression of p19Arf. Nat Commun. 2018;9:5452 pubmed publisher
|
- flow cytometry; mouse; loading ...; fig 5a
| Jogdand G, Sengupta S, Bhattacharya G, Singh S, Barik P, Devadas S. Inducible Costimulator Expressing T Cells Promote Parasitic Growth During Blood Stage Plasmodium berghei ANKA Infection. Front Immunol. 2018;9:1041 pubmed publisher
|
- flow cytometry; mouse; loading ...; fig 1g
| Omilusik K, Nadjsombati M, Shaw L, Yu B, Milner J, Goldrath A. Sustained Id2 regulation of E proteins is required for terminal differentiation of effector CD8+ T cells. J Exp Med. 2018;215:773-783 pubmed publisher
|
- flow cytometry; mouse; fig s6c
| Danahy D, Anthony S, Jensen I, Hartwig S, Shan Q, Xue H, et al. Polymicrobial sepsis impairs bystander recruitment of effector cells to infected skin despite optimal sensing and alarming function of skin resident memory CD8 T cells. PLoS Pathog. 2017;13:e1006569 pubmed publisher
|
- flow cytometry; human; fig 1b
| Kyoizumi S, Kubo Y, Kajimura J, Yoshida K, Hayashi T, Nakachi K, et al. Fate Decision Between Group 3 Innate Lymphoid and Conventional NK Cell Lineages by Notch Signaling in Human Circulating Hematopoietic Progenitors. J Immunol. 2017;199:2777-2793 pubmed publisher
|
- flow cytometry; mouse; loading ...; fig 2d
| Billerbeck E, Wolfisberg R, Fahnøe U, Xiao J, Quirk C, Luna J, et al. Mouse models of acute and chronic hepacivirus infection. Science. 2017;357:204-208 pubmed publisher
|
- flow cytometry; mouse; loading ...; fig 7c
| Daley D, Mani V, Mohan N, Akkad N, Pandian G, Savadkar S, et al. NLRP3 signaling drives macrophage-induced adaptive immune suppression in pancreatic carcinoma. J Exp Med. 2017;214:1711-1724 pubmed publisher
|
- flow cytometry; mouse; loading ...; fig 5g
| Daley D, Mani V, Mohan N, Akkad N, Ochi A, Heindel D, et al. Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance. Nat Med. 2017;23:556-567 pubmed publisher
|
- flow cytometry; mouse; loading ...; fig s1h
| Bouziat R, Hinterleitner R, Brown J, Stencel Baerenwald J, Ikizler M, Mayassi T, et al. Reovirus infection triggers inflammatory responses to dietary antigens and development of celiac disease. Science. 2017;356:44-50 pubmed publisher
|
- flow cytometry; human; loading ...; fig 2a
| Collins A, Rothman N, Liu K, Reiner S. Eomesodermin and T-bet mark developmentally distinct human natural killer cells. JCI Insight. 2017;2:e90063 pubmed publisher
|
- flow cytometry; mouse; loading ...; fig 1
| Rubtsova K, Rubtsov A, Thurman J, Mennona J, Kappler J, Marrack P. B cells expressing the transcription factor T-bet drive lupus-like autoimmunity. J Clin Invest. 2017;127:1392-1404 pubmed publisher
|
- flow cytometry; mouse; fig 3B
| Rampoldi F, Brunk F, Bonrouhi M, Federico G, Krunic D, Porubsky S, et al. Deficiency of N-myristoylation reveals calcineurin activity as regulator of IFN-?-producing ?? T cells. J Leukoc Biol. 2017;101:1005-1014 pubmed publisher
|
- flow cytometry; mouse; loading ...; fig 6b
| Hashimoto Hill S, Friesen L, Kim M, Kim C. Contraction of intestinal effector T cells by retinoic acid-induced purinergic receptor P2X7. Mucosal Immunol. 2017;10:912-923 pubmed publisher
|
- flow cytometry; mouse; fig 9d
| Cummings R, Barbet G, Bongers G, Hartmann B, Gettler K, Muniz L, et al. Different tissue phagocytes sample apoptotic cells to direct distinct homeostasis programs. Nature. 2016;539:565-569 pubmed publisher
|
- flow cytometry; human; fig 1b
| Cuff A, Robertson F, Stegmann K, Pallett L, Maini M, Davidson B, et al. Eomeshi NK Cells in Human Liver Are Long-Lived and Do Not Recirculate but Can Be Replenished from the Circulation. J Immunol. 2016;197:4283-4291 pubmed
|
- flow cytometry; mouse; loading ...; fig 2e
| Butcher M, Filipowicz A, Waseem T, McGary C, Crow K, Magilnick N, et al. Atherosclerosis-Driven Treg Plasticity Results in Formation of a Dysfunctional Subset of Plastic IFN?+ Th1/Tregs. Circ Res. 2016;119:1190-1203 pubmed publisher
|
- flow cytometry; human; loading ...; fig 5a
| Demers K, Makedonas G, Buggert M, Eller M, Ratcliffe S, Goonetilleke N, et al. Temporal Dynamics of CD8+ T Cell Effector Responses during Primary HIV Infection. PLoS Pathog. 2016;12:e1005805 pubmed publisher
|
- flow cytometry; mouse; loading ...; fig 5a
| Hwang S, Cobb D, Bhadra R, Youngblood B, Khan I. Blimp-1-mediated CD4 T cell exhaustion causes CD8 T cell dysfunction during chronic toxoplasmosis. J Exp Med. 2016;213:1799-818 pubmed publisher
|
- flow cytometry; mouse; loading ...; fig 5C
| Veinotte L, Gebremeskel S, Johnston B. CXCL16-positive dendritic cells enhance invariant natural killer T cell-dependent IFN? production and tumor control. Oncoimmunology. 2016;5:e1160979 pubmed publisher
|
- flow cytometry; human; fig s9
| Li W, Liu L, Gomez A, Zhang J, Ramadan A, Zhang Q, et al. Proteomics analysis reveals a Th17-prone cell population in presymptomatic graft-versus-host disease. JCI Insight. 2016;1: pubmed publisher
|
- flow cytometry; mouse; fig s1b, s5c
| Gomez de Agüero M, Ganal Vonarburg S, Fuhrer T, Rupp S, Uchimura Y, Li H, et al. The maternal microbiota drives early postnatal innate immune development. Science. 2016;351:1296-302 pubmed publisher
|
- flow cytometry; mouse; loading ...; fig 4
| Frodermann V, Van Duijn J, van Puijvelde G, van Santbrink P, Lagraauw H, de Vries M, et al. Heat-killed Staphylococcus aureus reduces atherosclerosis by inducing anti-inflammatory macrophages. J Intern Med. 2016;279:592-605 pubmed publisher
|
- flow cytometry; mouse; fig s4
| Kuipers H, Rieck M, Gurevich I, Nagy N, Butte M, Negrin R, et al. Hyaluronan synthesis is necessary for autoreactive T-cell trafficking, activation, and Th1 polarization. Proc Natl Acad Sci U S A. 2016;113:1339-44 pubmed publisher
|
- flow cytometry; mouse; loading ...; fig 3a
- immunocytochemistry; mouse; loading ...; fig 2c
| Metz P, Lopez J, Kim S, Akimoto K, Ohno S, Chang J. Regulation of Asymmetric Division by Atypical Protein Kinase C Influences Early Specification of CD8(+) T Lymphocyte Fates. Sci Rep. 2016;6:19182 pubmed publisher
|
- flow cytometry; mouse; fig 3
| Moretto M, Khan I. IL-21 Is Important for Induction of KLRG1+ Effector CD8 T Cells during Acute Intracellular Infection. J Immunol. 2016;196:375-84 pubmed publisher
|
- western blot; mouse; fig 4
| Hukelmann J, Anderson K, Sinclair L, Grzes K, Murillo A, Hawkins P, et al. The cytotoxic T cell proteome and its shaping by the kinase mTOR. Nat Immunol. 2016;17:104-12 pubmed publisher
|
- flow cytometry; human; loading ...; fig 2a
| Simonetta F, Pradier A, Bosshard C, Masouridi Levrat S, Chalandon Y, Roosnek E. NK Cell Functional Impairment after Allogeneic Hematopoietic Stem Cell Transplantation Is Associated with Reduced Levels of T-bet and Eomesodermin. J Immunol. 2015;195:4712-20 pubmed publisher
|
| Pearce V, Bouabe H, MacQueen A, Carbonaro V, Okkenhaug K. PI3Kδ Regulates the Magnitude of CD8+ T Cell Responses after Challenge with Listeria monocytogenes. J Immunol. 2015;195:3206-17 pubmed publisher
|
- flow cytometry; mouse; loading ...; fig 2e
| Ngiow S, Young A, Jacquelot N, Yamazaki T, Enot D, Zitvogel L, et al. A Threshold Level of Intratumor CD8+ T-cell PD1 Expression Dictates Therapeutic Response to Anti-PD1. Cancer Res. 2015;75:3800-11 pubmed publisher
|
- flow cytometry; mouse; loading ...; fig s2
| Kim M, Taparowsky E, Kim C. Retinoic Acid Differentially Regulates the Migration of Innate Lymphoid Cell Subsets to the Gut. Immunity. 2015;43:107-19 pubmed publisher
|
- flow cytometry; mouse; fig 4b
| Weigelin B, Bolaños E, Teijeira A, Martinez Forero I, Labiano S, Azpilikueta A, et al. Focusing and sustaining the antitumor CTL effector killer response by agonist anti-CD137 mAb. Proc Natl Acad Sci U S A. 2015;112:7551-6 pubmed publisher
|
- flow cytometry; mouse; fig 5
| Holm J, Sorobetea D, Kiilerich P, Ramayo Caldas Y, Estellé J, Ma T, et al. Chronic Trichuris muris Infection Decreases Diversity of the Intestinal Microbiota and Concomitantly Increases the Abundance of Lactobacilli. PLoS ONE. 2015;10:e0125495 pubmed publisher
|
| Thiault N, Darrigues J, Adoue V, Gros M, Binet B, Pérals C, et al. Peripheral regulatory T lymphocytes recirculating to the thymus suppress the development of their precursors. Nat Immunol. 2015;16:628-34 pubmed publisher
|
| Dahlgren M, Gustafsson Hedberg T, Livingston M, Cucak H, Alsén S, Yrlid U, et al. T follicular helper, but not Th1, cell differentiation in the absence of conventional dendritic cells. J Immunol. 2015;194:5187-99 pubmed publisher
|
- flow cytometry; mouse; fig 7
| Van Den Ham K, Shio M, Rainone A, Fournier S, Krawczyk C, Olivier M. Iron prevents the development of experimental cerebral malaria by attenuating CXCR3-mediated T cell chemotaxis. PLoS ONE. 2015;10:e0118451 pubmed publisher
|
- flow cytometry; mouse; fig 1
| Wensveen F, JelenÄić V, Valentić S, Å estan M, Wensveen T, Theurich S, et al. NK cells link obesity-induced adipose stress to inflammation and insulin resistance. Nat Immunol. 2015;16:376-85 pubmed publisher
|
| Dobenecker M, Kim J, Marcello J, Fang T, Prinjha R, Bosselut R, et al. Coupling of T cell receptor specificity to natural killer T cell development by bivalent histone H3 methylation. J Exp Med. 2015;212:297-306 pubmed publisher
|
- flow cytometry; human; fig 5
| Dimova T, Brouwer M, Gosselin F, Tassignon J, Leo O, Donner C, et al. Effector Vγ9Vδ2 T cells dominate the human fetal γδ T-cell repertoire. Proc Natl Acad Sci U S A. 2015;112:E556-65 pubmed publisher
|
- flow cytometry; mouse; fig s2
| Clouthier D, Zhou A, Wortzman M, Luft O, Levy G, Watts T. GITR intrinsically sustains early type 1 and late follicular helper CD4 T cell accumulation to control a chronic viral infection. PLoS Pathog. 2015;11:e1004517 pubmed publisher
|
| Spada R, Rojas J, Pérez Yagüe S, Mulens V, Cannata Ortiz P, Bragado R, et al. NKG2D ligand overexpression in lupus nephritis correlates with increased NK cell activity and differentiation in kidneys but not in the periphery. J Leukoc Biol. 2015;97:583-98 pubmed publisher
|
- flow cytometry; mouse; fig 5
| Teixeira L, Moreira J, Melo J, Bezerra F, Marques R, Ferreirinha P, et al. Immune response in the adipose tissue of lean mice infected with the protozoan parasite Neospora caninum. Immunology. 2015;145:242-57 pubmed publisher
|
- flow cytometry; mouse; fig s5
| Shrestha S, Yang K, Guy C, Vogel P, Neale G, Chi H. Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses. Nat Immunol. 2015;16:178-87 pubmed publisher
|
- flow cytometry; human; fig 4
- western blot; human; 1:250
| Bürgler S, Gimeno A, Parente Ribes A, Wang D, Os A, Devereux S, et al. Chronic lymphocytic leukemia cells express CD38 in response to Th1 cell-derived IFN-γ by a T-bet-dependent mechanism. J Immunol. 2015;194:827-35 pubmed publisher
|
| Stoycheva D, Deiser K, Stärck L, Nishanth G, Schlüter D, Uckert W, et al. IFN-γ regulates CD8+ memory T cell differentiation and survival in response to weak, but not strong, TCR signals. J Immunol. 2015;194:553-9 pubmed publisher
|
| Setoguchi R, Matsui Y, Mouri K. mTOR signaling promotes a robust and continuous production of IFN-γ by human memory CD8+ T cells and their proliferation. Eur J Immunol. 2015;45:893-902 pubmed publisher
|
| Rutz S, Kayagaki N, Phung Q, Eidenschenk C, Noubade R, Wang X, et al. Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells. Nature. 2015;518:417-21 pubmed publisher
|
| Gerner W, Talker S, Koinig H, Sedlak C, Mair K, Saalmüller A. Phenotypic and functional differentiation of porcine αβ T cells: current knowledge and available tools. Mol Immunol. 2015;66:3-13 pubmed publisher
|
- flow cytometry; mouse; fig 6
| Edwards C, Best S, Gun S, Claser C, James K, de Oca M, et al. Spatiotemporal requirements for IRF7 in mediating type I IFN-dependent susceptibility to blood-stage Plasmodium infection. Eur J Immunol. 2015;45:130-41 pubmed publisher
|
- flow cytometry; human; fig 5
| Ziblat A, Domaica C, Spallanzani R, Iraolagoitia X, Rossi L, Avila D, et al. IL-27 stimulates human NK-cell effector functions and primes NK cells for IL-18 responsiveness. Eur J Immunol. 2015;45:192-202 pubmed publisher
|
- flow cytometry; mouse; fig 5
| Donaldson D, Bradford B, Artis D, Mabbott N. Reciprocal regulation of lymphoid tissue development in the large intestine by IL-25 and IL-23. Mucosal Immunol. 2015;8:582-95 pubmed publisher
|
| Vogelzang A, Perdomo C, Zedler U, Kuhlmann S, Hurwitz R, Gengenbacher M, et al. Central memory CD4+ T cells are responsible for the recombinant Bacillus Calmette-Guérin ?ureC::hly vaccine's superior protection against tuberculosis. J Infect Dis. 2014;210:1928-37 pubmed publisher
|
| Smith N, Wissink E, Wang J, Pinello J, Davenport M, Grimson A, et al. Rapid proliferation and differentiation impairs the development of memory CD8+ T cells in early life. J Immunol. 2014;193:177-84 pubmed publisher
|
| Deng N, Weaver J, Mosmann T. Cytokine diversity in the Th1-dominated human anti-influenza response caused by variable cytokine expression by Th1 cells, and a minor population of uncommitted IL-2+IFN?- Thpp cells. PLoS ONE. 2014;9:e95986 pubmed publisher
|
- flow cytometry; mouse; fig 3
| Samuelson E, Laird R, Papillion A, Tatum A, Princiotta M, Hayes S. Reduced B lymphoid kinase (Blk) expression enhances proinflammatory cytokine production and induces nephrosis in C57BL/6-lpr/lpr mice. PLoS ONE. 2014;9:e92054 pubmed publisher
|
- immunocytochemistry; mouse
| Jung H, Song K, Chang J, Doh J. Geometrically controlled asymmetric division of CD4+ T cells studied by immunological synapse arrays. PLoS ONE. 2014;9:e91926 pubmed publisher
|
| Lee J, Walsh M, Hoehn K, James D, Wherry E, Choi Y. Regulator of fatty acid metabolism, acetyl coenzyme a carboxylase 1, controls T cell immunity. J Immunol. 2014;192:3190-9 pubmed publisher
|
- flow cytometry; human; tbl 1
| Magri G, Miyajima M, Bascones S, Mortha A, Puga I, Cassis L, et al. Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells. Nat Immunol. 2014;15:354-364 pubmed publisher
|
| Kim E, Gasper D, Lee S, Plisch E, Svaren J, Suresh M. Bach2 regulates homeostasis of Foxp3+ regulatory T cells and protects against fatal lung disease in mice. J Immunol. 2014;192:985-95 pubmed publisher
|
| Sambucci M, Laudisi F, Novelli F, Bennici E, Rosado M, Pioli C. Effects of PARP-1 deficiency on Th1 and Th2 cell differentiation. ScientificWorldJournal. 2013;2013:375024 pubmed publisher
|
| Powell N, Walker A, Stolarczyk E, Canavan J, Gökmen M, Marks E, et al. The transcription factor T-bet regulates intestinal inflammation mediated by interleukin-7 receptor+ innate lymphoid cells. Immunity. 2012;37:674-84 pubmed publisher
|
| Zhang N, Bevan M. TGF-? signaling to T cells inhibits autoimmunity during lymphopenia-driven proliferation. Nat Immunol. 2012;13:667-73 pubmed publisher
|
| Randall K, Chan S, Ma C, Fung I, Mei Y, Yabas M, et al. DOCK8 deficiency impairs CD8 T cell survival and function in humans and mice. J Exp Med. 2011;208:2305-20 pubmed publisher
|
| Kim D, Park H, Lim S, Koo J, Lee H, Choi J, et al. Regulation of chitinase-3-like-1 in T cell elicits Th1 and cytotoxic responses to inhibit lung metastasis. Nat Commun. 2018;9:503 pubmed publisher
|
| Gaya M, Barral P, Burbage M, Aggarwal S, Montaner B, Warren Navia A, et al. Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells. Cell. 2018;172:517-533.e20 pubmed publisher
|
| Brownlie R, Garcia C, Ravasz M, Zehn D, Salmond R, Zamoyska R. Resistance to TGFβ suppression and improved anti-tumor responses in CD8+ T cells lacking PTPN22. Nat Commun. 2017;8:1343 pubmed publisher
|
| Minter M, Hinterleitner R, Meisel M, Zhang C, Leone V, Zhang X, et al. Antibiotic-induced perturbations in microbial diversity during post-natal development alters amyloid pathology in an aged APPSWE/PS1ΔE9 murine model of Alzheimer's disease. Sci Rep. 2017;7:10411 pubmed publisher
|
| Cuff A, Male V. Conventional NK cells and ILC1 are partially ablated in the livers of Ncr1 iCreTbx21 fl/fl mice. Wellcome Open Res. 2017;2:39 pubmed publisher
|
| Vasanthakumar A, Xu D, Lun A, Kueh A, van Gisbergen K, Iannarella N, et al. A non-canonical function of Ezh2 preserves immune homeostasis. EMBO Rep. 2017;18:619-631 pubmed publisher
|
| Roberts E, Carnathan D, Li H, Shaw G, Silvestri G, Betts M. Collapse of Cytolytic Potential in SIV-Specific CD8+ T Cells Following Acute SIV Infection in Rhesus Macaques. PLoS Pathog. 2016;12:e1006135 pubmed publisher
|
| Martínez Gómez J, Periasamy P, Dutertre C, Irving A, Ng J, Crameri G, et al. Phenotypic and functional characterization of the major lymphocyte populations in the fruit-eating bat Pteropus alecto. Sci Rep. 2016;6:37796 pubmed publisher
|
| Li K, Baird M, Yang J, Jackson C, Ronchese F, Young S. Conditions for the generation of cytotoxic CD4(+) Th cells that enhance CD8(+) CTL-mediated tumor regression. Clin Transl Immunology. 2016;5:e95 pubmed publisher
|
| Clever D, Roychoudhuri R, Constantinides M, Askenase M, Sukumar M, Klebanoff C, et al. Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche. Cell. 2016;166:1117-1131.e14 pubmed publisher
|
| O Leary C, Riling C, Spruce L, Ding H, Kumar S, Deng G, et al. Ndfip-mediated degradation of Jak1 tunes cytokine signalling to limit expansion of CD4+ effector T cells. Nat Commun. 2016;7:11226 pubmed publisher
|
| Shen W, Hixon J, McLean M, Li W, Durum S. IL-22-Expressing Murine Lymphocytes Display Plasticity and Pathogenicity in Reporter Mice. Front Immunol. 2015;6:662 pubmed publisher
|
| Younis R, Han K, Webb T. Human Head and Neck Squamous Cell Carcinoma-Associated Semaphorin 4D Induces Expansion of Myeloid-Derived Suppressor Cells. J Immunol. 2016;196:1419-29 pubmed publisher
|
| Mackay L, Wynne Jones E, Freestone D, Pellicci D, Mielke L, Newman D, et al. T-box Transcription Factors Combine with the Cytokines TGF-β and IL-15 to Control Tissue-Resident Memory T Cell Fate. Immunity. 2015;43:1101-11 pubmed publisher
|
| Carrascal J, Carrillo J, Arpa B, Egia Mendikute L, Rosell Mases E, Pujol Autonell I, et al. B-cell anergy induces a Th17 shift in a novel B lymphocyte transgenic NOD mouse model, the 116C-NOD mouse. Eur J Immunol. 2016;46:593-608 pubmed publisher
|
| Luci C, Bekri S, Bihl F, Pini J, Bourdely P, Nouhen K, et al. NKp46+ Innate Lymphoid Cells Dampen Vaginal CD8 T Cell Responses following Local Immunization with a Cholera Toxin-Based Vaccine. PLoS ONE. 2015;10:e0143224 pubmed publisher
|
| Hoffmann M, Molina Mendiola C, Nelson A, Parks C, Reyes E, Hansen M, et al. Co-potentiation of antigen recognition: A mechanism to boost weak T cell responses and provide immunotherapy in vivo. Sci Adv. 2015;1:e1500415 pubmed publisher
|
| Omilusik K, Best J, Yu B, Goossens S, Weidemann A, Nguyen J, et al. Transcriptional repressor ZEB2 promotes terminal differentiation of CD8+ effector and memory T cell populations during infection. J Exp Med. 2015;212:2027-39 pubmed publisher
|
| Deng Y, Yang Y, Wang S, Li F, Liu M, Hua Q, et al. Intranasal Administration of Lentiviral miR-135a Regulates Mast Cell and Allergen-Induced Inflammation by Targeting GATA-3. PLoS ONE. 2015;10:e0139322 pubmed publisher
|
| Goyvaerts C, Broos K, Escors D, Heirman C, Raes G, De Baetselier P, et al. The transduction pattern of IL-12-encoding lentiviral vectors shapes the immunological outcome. Eur J Immunol. 2015;45:3351-61 pubmed publisher
|
| Dey M, Chang A, Miska J, Wainwright D, Ahmed A, Balyasnikova I, et al. Dendritic Cell-Based Vaccines that Utilize Myeloid Rather than Plasmacytoid Cells Offer a Superior Survival Advantage in Malignant Glioma. J Immunol. 2015;195:367-76 pubmed publisher
|
| Kornete M, Mason E, Girouard J, Lafferty E, Qureshi S, Piccirillo C. Th1-Like ICOS+ Foxp3+ Treg Cells Preferentially Express CXCR3 and Home to β-Islets during Pre-Diabetes in BDC2.5 NOD Mice. PLoS ONE. 2015;10:e0126311 pubmed publisher
|
| Pollizzi K, Patel C, Sun I, Oh M, Waickman A, Wen J, et al. mTORC1 and mTORC2 selectively regulate CD8⺠T cell differentiation. J Clin Invest. 2015;125:2090-108 pubmed publisher
|
| Hong M, Sandalova E, Low D, Gehring A, Fieni S, Amadei B, et al. Trained immunity in newborn infants of HBV-infected mothers. Nat Commun. 2015;6:6588 pubmed publisher
|
| Henderson J, Opejin A, Jones A, Gross C, Hawiger D. CD5 instructs extrathymic regulatory T cell development in response to self and tolerizing antigens. Immunity. 2015;42:471-83 pubmed publisher
|
| Yang M, Li D, Chang Z, Yang Z, Tian Z, Dong Z. PDK1 orchestrates early NK cell development through induction of E4BP4 expression and maintenance of IL-15 responsiveness. J Exp Med. 2015;212:253-65 pubmed publisher
|
| Metz P, Arsenio J, Kakaradov B, Kim S, Remedios K, Oakley K, et al. Regulation of asymmetric division and CD8+ T lymphocyte fate specification by protein kinase Cζ and protein kinase Cλ/ι. J Immunol. 2015;194:2249-59 pubmed publisher
|
| Mackley E, Houston S, Marriott C, Halford E, LUCAS B, Cerovic V, et al. CCR7-dependent trafficking of RORγ⺠ILCs creates a unique microenvironment within mucosal draining lymph nodes. Nat Commun. 2015;6:5862 pubmed publisher
|
| Lynch L, Michelet X, Zhang S, Brennan P, Moseman A, Lester C, et al. Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of T(reg) cells and macrophages in adipose tissue. Nat Immunol. 2015;16:85-95 pubmed publisher
|
| Buchan S, Manzo T, Flutter B, Rogel A, Edwards N, Zhang L, et al. OX40- and CD27-mediated costimulation synergizes with anti-PD-L1 blockade by forcing exhausted CD8+ T cells to exit quiescence. J Immunol. 2015;194:125-133 pubmed publisher
|
| Tang W, Wang H, Claudio E, Tassi I, Ha H, Saret S, et al. The oncoprotein and transcriptional regulator Bcl-3 governs plasticity and pathogenicity of autoimmune T cells. Immunity. 2014;41:555-66 pubmed publisher
|
| Linterman M, Denton A, Divekar D, Zvetkova I, Kane L, Ferreira C, et al. CD28 expression is required after T cell priming for helper T cell responses and protective immunity to infection. elife. 2014;3: pubmed publisher
|
| Drummond R, Wallace C, Reid D, Way S, Kaplan D, Brown G. Cutting edge: Failure of antigen-specific CD4+ T cell recruitment to the kidney during systemic candidiasis. J Immunol. 2014;193:5381-5 pubmed publisher
|
| Araya N, Sato T, Ando H, Tomaru U, Yoshida M, Coler Reilly A, et al. HTLV-1 induces a Th1-like state in CD4+CCR4+ T cells. J Clin Invest. 2014;124:3431-42 pubmed publisher
|
| Park J, Kim M, Kang S, Jannasch A, Cooper B, Patterson J, et al. Short-chain fatty acids induce both effector and regulatory T cells by suppression of histone deacetylases and regulation of the mTOR-S6K pathway. Mucosal Immunol. 2015;8:80-93 pubmed publisher
|
| Sarrabayrouse G, Bossard C, Chauvin J, Jarry A, Meurette G, Quévrain E, et al. CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. PLoS Biol. 2014;12:e1001833 pubmed publisher
|
| Heikamp E, Patel C, Collins S, Waickman A, Oh M, Sun I, et al. The AGC kinase SGK1 regulates TH1 and TH2 differentiation downstream of the mTORC2 complex. Nat Immunol. 2014;15:457-64 pubmed publisher
|
| Li C, Mueller E, Bradley L. Islet antigen-specific Th17 cells can induce TNF-?-dependent autoimmune diabetes. J Immunol. 2014;192:1425-32 pubmed publisher
|
| Clancy Thompson E, King L, Nunnley L, Mullins I, Slingluff C, Mullins D. Peptide vaccination in Montanide adjuvant induces and GM-CSF increases CXCR3 and cutaneous lymphocyte antigen expression by tumor antigen-specific CD8 T cells. Cancer Immunol Res. 2013;1:332-9 pubmed publisher
|
| Eberstål S, Sandén E, Fritzell S, Darabi A, Visse E, Siesjo P. Intratumoral COX-2 inhibition enhances GM-CSF immunotherapy against established mouse GL261 brain tumors. Int J Cancer. 2014;134:2748-53 pubmed publisher
|
| Mollo S, Ingram J, Kress R, Zajac A, Harrington L. Virus-specific CD4 and CD8 T cell responses in the absence of Th1-associated transcription factors. J Leukoc Biol. 2014;95:705-713 pubmed
|
| Hu T, Wang H, Simmons A, Bajana S, Zhao Y, Kovats S, et al. Increased level of E protein activity during invariant NKT development promotes differentiation of invariant NKT2 and invariant NKT17 subsets. J Immunol. 2013;191:5065-73 pubmed publisher
|
| KEMP K, Lin Z, Zhao F, Gao B, Song J, Zhang K, et al. The serine-threonine kinase inositol-requiring enzyme 1? (IRE1?) promotes IL-4 production in T helper cells. J Biol Chem. 2013;288:33272-82 pubmed publisher
|
| Carbo A, Bassaganya Riera J, Pedragosa M, Viladomiu M, Marathe M, Eubank S, et al. Predictive computational modeling of the mucosal immune responses during Helicobacter pylori infection. PLoS ONE. 2013;8:e73365 pubmed publisher
|
| Sharma A, Berga Bolaños R, Sultana D, Sen J. IL-4 and IL-4 receptor expression is dispensable for the development and function of natural killer T cells. PLoS ONE. 2013;8:e71872 pubmed publisher
|
| Chen Q, Yan L, Wang C, Wang W, Shi H, Su B, et al. Mesenchymal stem cells alleviate TNBS-induced colitis by modulating inflammatory and autoimmune responses. World J Gastroenterol. 2013;19:4702-17 pubmed publisher
|
| Bailis W, Yashiro Ohtani Y, Fang T, Hatton R, Weaver C, Artis D, et al. Notch simultaneously orchestrates multiple helper T cell programs independently of cytokine signals. Immunity. 2013;39:148-59 pubmed publisher
|
| Tejera M, Kim E, Sullivan J, Plisch E, Suresh M. FoxO1 controls effector-to-memory transition and maintenance of functional CD8 T cell memory. J Immunol. 2013;191:187-99 pubmed publisher
|
| Edwards J, Fujii H, Zhou A, Creemers J, Unutmaz D, Shevach E. Regulation of the expression of GARP/latent TGF-β1 complexes on mouse T cells and their role in regulatory T cell and Th17 differentiation. J Immunol. 2013;190:5506-15 pubmed publisher
|
| Tse S, Cockburn I, Zhang H, Scott A, Zavala F. Unique transcriptional profile of liver-resident memory CD8+ T cells induced by immunization with malaria sporozoites. Genes Immun. 2013;14:302-9 pubmed publisher
|
| Amoah S, Holbrook B, Yammani R, Alexander Miller M. High viral burden restricts short-lived effector cell number at late times postinfection through increased natural regulatory T cell expansion. J Immunol. 2013;190:5020-9 pubmed publisher
|
| Yang M, Sim S, Jeon J, Jeong E, Kim H, Park Y, et al. Mitral and tufted cells are potential cellular targets of nitration in the olfactory bulb of aged mice. PLoS ONE. 2013;8:e59673 pubmed publisher
|
| Filtjens J, Taveirne S, Van Acker A, Van Ammel E, Vanhees M, Kerre T, et al. Abundant stage-dependent Ly49E expression by liver NK cells is not essential for their differentiation and function. J Leukoc Biol. 2013;93:699-711 pubmed publisher
|
| Kleinewietfeld M, Manzel A, Titze J, Kvakan H, Yosef N, Linker R, et al. Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells. Nature. 2013;496:518-22 pubmed publisher
|
| Himmel M, Macdonald K, Garcia R, Steiner T, Levings M. Helios+ and Helios- cells coexist within the natural FOXP3+ T regulatory cell subset in humans. J Immunol. 2013;190:2001-8 pubmed publisher
|
| Sciumè G, Hirahara K, Takahashi H, Laurence A, Villarino A, Singleton K, et al. Distinct requirements for T-bet in gut innate lymphoid cells. J Exp Med. 2012;209:2331-8 pubmed publisher
|
| Patakas A, Benson R, Withers D, Conigliaro P, McInnes I, Brewer J, et al. Th17 effector cells support B cell responses outside of germinal centres. PLoS ONE. 2012;7:e49715 pubmed publisher
|
| Dutra M, Béla S, Peixoto Rangel A, Fakiola M, Cruz A, Gazzinelli A, et al. Association of a NOD2 gene polymorphism and T-helper 17 cells with presumed ocular toxoplasmosis. J Infect Dis. 2013;207:152-63 pubmed publisher
|
| Schroeter M, Ratsch B, Lehmann J, Baumgrass R, Hamann A, Syrbe U. Differential regulation and impact of fucosyltransferase VII and core 2 ?1,6-N-acetyl-glycosaminyltransferase for generation of E-selectin and P-selectin ligands in murine CD4+ T cells. Immunology. 2012;137:294-304 pubmed publisher
|
| Zhao J, Zhao J, Perlman S. Differential effects of IL-12 on Tregs and non-Treg T cells: roles of IFN-?, IL-2 and IL-2R. PLoS ONE. 2012;7:e46241 pubmed publisher
|
| Larochelle C, Cayrol R, Kebir H, Alvarez J, Lécuyer M, Ifergan I, et al. Melanoma cell adhesion molecule identifies encephalitogenic T lymphocytes and promotes their recruitment to the central nervous system. Brain. 2012;135:2906-24 pubmed publisher
|
| Shatynski K, Chen H, Kwon J, Williams M. Decreased STAT5 phosphorylation and GATA-3 expression in NOX2-deficient T cells: role in T helper development. Eur J Immunol. 2012;42:3202-11 pubmed publisher
|
| Weiss R, Hessenberger M, Kitzmüller S, Bach D, Weinberger E, Krautgartner W, et al. Transcutaneous vaccination via laser microporation. J Control Release. 2012;162:391-9 pubmed publisher
|
| Sharma A, Chen Q, Nguyen T, Yu Q, Sen J. T cell factor-1 and β-catenin control the development of memory-like CD8 thymocytes. J Immunol. 2012;188:3859-68 pubmed publisher
|
| Jurado J, Pasquinelli V, Alvarez I, Peña D, Rovetta A, Tateosian N, et al. IL-17 and IFN-? expression in lymphocytes from patients with active tuberculosis correlates with the severity of the disease. J Leukoc Biol. 2012;91:991-1002 pubmed publisher
|
| Li Q, Rao R, Vazzana J, Goedegebuure P, Odunsi K, Gillanders W, et al. Regulating mammalian target of rapamycin to tune vaccination-induced CD8(+) T cell responses for tumor immunity. J Immunol. 2012;188:3080-7 pubmed publisher
|
| Radulovic K, Manta C, Rossini V, Holzmann K, Kestler H, Wegenka U, et al. CD69 regulates type I IFN-induced tolerogenic signals to mucosal CD4 T cells that attenuate their colitogenic potential. J Immunol. 2012;188:2001-13 pubmed publisher
|
| Hansmann L, Schmidl C, Kett J, Steger L, Andreesen R, Hoffmann P, et al. Dominant Th2 differentiation of human regulatory T cells upon loss of FOXP3 expression. J Immunol. 2012;188:1275-82 pubmed publisher
|
| Almolda B, Costa M, Montoya M, Gonzalez B, Castellano B. Increase in Th17 and T-reg lymphocytes and decrease of IL22 correlate with the recovery phase of acute EAE in rat. PLoS ONE. 2011;6:e27473 pubmed publisher
|
| Gordy L, Bezbradica J, Flyak A, Spencer C, Dunkle A, Sun J, et al. IL-15 regulates homeostasis and terminal maturation of NKT cells. J Immunol. 2011;187:6335-45 pubmed publisher
|
| LaCasse C, Janikashvili N, Larmonier C, Alizadeh D, Hanke N, Kartchner J, et al. Th-1 lymphocytes induce dendritic cell tumor killing activity by an IFN-?-dependent mechanism. J Immunol. 2011;187:6310-7 pubmed publisher
|
| Yabas M, Godfrey D, Goodnow C, Hoyne G. Differential requirement for the CD45 splicing regulator hnRNPLL for accumulation of NKT and conventional T cells. PLoS ONE. 2011;6:e26440 pubmed publisher
|
| Nakahira M, Nakanishi K. Requirement of GATA-binding protein 3 for II13 gene expression in IL-18-stimulated Th1 cells. Int Immunol. 2011;23:761-72 pubmed publisher
|
| Qui H, Hagymasi A, Bandyopadhyay S, St Rose M, Ramanarasimhaiah R, Menoret A, et al. CD134 plus CD137 dual costimulation induces Eomesodermin in CD4 T cells to program cytotoxic Th1 differentiation. J Immunol. 2011;187:3555-64 pubmed publisher
|
| Bertossi A, Aichinger M, Sansonetti P, Lech M, Neff F, Pal M, et al. Loss of Roquin induces early death and immune deregulation but not autoimmunity. J Exp Med. 2011;208:1749-56 pubmed publisher
|
| Haque A, Best S, Ammerdorffer A, Desbarrieres L, de Oca M, Amante F, et al. Type I interferons suppress CD4? T-cell-dependent parasite control during blood-stage Plasmodium infection. Eur J Immunol. 2011;41:2688-98 pubmed publisher
|
| Hebenstreit D, Fang M, Gu M, Charoensawan V, van Oudenaarden A, Teichmann S. RNA sequencing reveals two major classes of gene expression levels in metazoan cells. Mol Syst Biol. 2011;7:497 pubmed publisher
|
| Lu Y, Malmhäll C, Sjöstrand M, Radinger M, O Neil S, Lotvall J, et al. Expansion of CD4(+) CD25(+) and CD25(-) T-Bet, GATA-3, Foxp3 and ROR?t cells in allergic inflammation, local lung distribution and chemokine gene expression. PLoS ONE. 2011;6:e19889 pubmed publisher
|
| El Behi M, Ciric B, Dai H, Yan Y, Cullimore M, Safavi F, et al. The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF. Nat Immunol. 2011;12:568-75 pubmed publisher
|
| Gaddis D, Michalek S, Katz J. TLR4 signaling via MyD88 and TRIF differentially shape the CD4+ T cell response to Porphyromonas gingivalis hemagglutinin B. J Immunol. 2011;186:5772-83 pubmed publisher
|
| Erhardt A, Wegscheid C, Claass B, Carambia A, Herkel J, Mittrücker H, et al. CXCR3 deficiency exacerbates liver disease and abrogates tolerance in a mouse model of immune-mediated hepatitis. J Immunol. 2011;186:5284-93 pubmed publisher
|
| Haabeth O, Lorvik K, Hammarstrom C, Donaldson I, Haraldsen G, Bogen B, et al. Inflammation driven by tumour-specific Th1 cells protects against B-cell cancer. Nat Commun. 2011;2:240 pubmed publisher
|
| Lexberg M, Taubner A, Albrecht I, Lepenies I, Richter A, Kamradt T, et al. IFN-? and IL-12 synergize to convert in vivo generated Th17 into Th1/Th17 cells. Eur J Immunol. 2010;40:3017-27 pubmed publisher
|
| Hendricks D, Fink P. Recent thymic emigrants are biased against the T-helper type 1 and toward the T-helper type 2 effector lineage. Blood. 2011;117:1239-49 pubmed publisher
|
| Castillo E, Acero L, Stonier S, Zhou D, Schluns K. Thymic and peripheral microenvironments differentially mediate development and maturation of iNKT cells by IL-15 transpresentation. Blood. 2010;116:2494-503 pubmed publisher
|
| Ness Schwickerath K, Jin C, Morita C. Cytokine requirements for the differentiation and expansion of IL-17A- and IL-22-producing human Vgamma2Vdelta2 T cells. J Immunol. 2010;184:7268-80 pubmed publisher
|
| KEMP K, Levin S, Bryce P, Stein P. Lck mediates Th2 differentiation through effects on T-bet and GATA-3. J Immunol. 2010;184:4178-84 pubmed publisher
|
| Xie Y, Akpinarli A, Maris C, Hipkiss E, Lane M, Kwon E, et al. Naive tumor-specific CD4(+) T cells differentiated in vivo eradicate established melanoma. J Exp Med. 2010;207:651-67 pubmed publisher
|
| Mjösberg J, Berg G, Jenmalm M, Ernerudh J. FOXP3+ regulatory T cells and T helper 1, T helper 2, and T helper 17 cells in human early pregnancy decidua. Biol Reprod. 2010;82:698-705 pubmed publisher
|
| Torii M, Wang L, Ma N, Saito K, Hori T, Sato Ueshima M, et al. Thioredoxin suppresses airway inflammation independently of systemic Th1/Th2 immune modulation. Eur J Immunol. 2010;40:787-96 pubmed publisher
|
| Doisne J, Bartholin L, Yan K, Garcia C, Duarte N, Le Luduec J, et al. iNKT cell development is orchestrated by different branches of TGF-beta signaling. J Exp Med. 2009;206:1365-78 pubmed publisher
|
| Imanguli M, Swaim W, League S, Gress R, Pavletic S, Hakim F. Increased T-bet+ cytotoxic effectors and type I interferon-mediated processes in chronic graft-versus-host disease of the oral mucosa. Blood. 2009;113:3620-30 pubmed publisher
|
| Tschop J, Martignoni A, Reid M, Adediran S, Gardner J, Noel G, et al. Differential immunological phenotypes are exhibited after scald and flame burns. Shock. 2009;31:157-63 pubmed publisher
|
| Usui T, Preiss J, Kanno Y, Yao Z, Bream J, O Shea J, et al. T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription. J Exp Med. 2006;203:755-66 pubmed
|
| Hwang E, Hong J, Glimcher L. IL-2 production in developing Th1 cells is regulated by heterodimerization of RelA and T-bet and requires T-bet serine residue 508. J Exp Med. 2005;202:1289-300 pubmed
|
| Dorfman D, van den Elzen P, Weng A, Shahsafaei A, Glimcher L. Differential expression of T-bet, a T-box transcription factor required for Th1 T-cell development, in peripheral T-cell lymphomas. Am J Clin Pathol. 2003;120:866-73 pubmed
|
| Szabo S, Kim S, Costa G, Zhang X, Fathman C, Glimcher L. A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell. 2000;100:655-69 pubmed
|