MASH1 Monoclonal Antibody (24B72D11), eBioscience™ | Invitrogen 14-5794-80 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

MASH1 Monoclonal Antibody (24B72D11), eBioscience™

catalog :

14-5794-80

quantity :

25 µg

price :

US 309.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

24B72D11

reactivity :

mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; 1:100; fig s8	Liu Q, Sanai N, Jin W, La Cava A, Van Kaer L, Shi F. Neural stem cells sustain natural killer cells that dictate recovery from brain inflammation. Nat Neurosci. 2016;19:243-52 pubmed publisher
	Stupnikov M, Yang Y, Mori M, LU J, Cardoso W. Jagged and Delta-like ligands control distinct events during airway progenitor cell differentiation. elife. 2019;8: pubmed publisher
	Wagner A, Devarakonda S, Skidmore Z, Krysiak K, Ramu A, Trani L, et al. Recurrent WNT pathway alterations are frequent in relapsed small cell lung cancer. Nat Commun. 2018;9:3787 pubmed publisher
	Brzezinski J, Kim E, Johnson J, Reh T. Ascl1 expression defines a subpopulation of lineage-restricted progenitors in the mammalian retina. Development. 2011;138:3519-31 pubmed publisher
	Nefzger C, Haynes J, Pouton C. Directed expression of Gata2, Mash1, and Foxa2 synergize to induce the serotonergic neuron phenotype during in vitro differentiation of embryonic stem cells. Stem Cells. 2011;29:928-39 pubmed publisher
	Yun K, Fischman S, Johnson J, Hrabe de Angelis M, Weinmaster G, Rubenstein J. Modulation of the notch signaling by Mash1 and Dlx1/2 regulates sequential specification and differentiation of progenitor cell types in the subcortical telencephalon. Development. 2002;129:5029-40 pubmed

product information

Product Type :

Antibody

Product Name :

MASH1 Monoclonal Antibody (24B72D11), eBioscience™

Catalog # :

14-5794-80

Quantity :

25 µg

Price :

US 309.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Mouse, Rat

Applications :

Immunocytochemistry: 20 µg/mL, Immunohistochemistry (Frozen): Assay-Dependent, Western Blot: 5 µg/mL

Species :

Mouse, Rat

Clone :

24B72D11

Isotype :

IgG1, kappa

Storage :

4° C

Description :

ASCL1 (also known as ASH1) is a basic helix-loop-helix transcription factor that is required for early development of the nervous system. Expressed in fetal brain, ASCL1 is essential for the proper development of autonomic neurons and for the survival of subsets of autonomic neurons. ASCL1 interaction with MEF-2A may regulate the expression of specific genes that are critical for the formation of distinct neuronal circuits within the central nervous system. The high level of ASCL1 expression in neuroendocrine tumors, such as medullary thyroid cancer, small cell lung cancer and lung cancer with neuroendocrine features may provide a useful marker for cancers with neuroendocrine features. Mapping to human chromosome 12, the ASCL1 gene contains a trinucleotide repeat region, making this locus a candidate for inherited disease.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 20 µg/mL, Immunohistochemistry (Frozen): Assay-Dependent, Western Blot: 5 µg/mL

Aliases :

achaete scute protein; achaete-scute complex homolog 1; achaete-scute complex homolog 1 (Drosophila); achaete-scute complex homolog-like 1; achaete-scute complex-like 1; achaete-scute complex-like protein 1; achaete-scute family bHLH transcription factor 1; achaete-scute homolog 1; AI225900; Ascl1; ASH1; ASH-1; bHLHa46; Class A basic helix-loop-helix protein 46; HASH1; KMT2H; mammalian achaete scute homolog 1; Mash1; mASH-1

more info or order :

Invitrogen product webpage