MICA/B Monoclonal Antibody (6D4), eBioscience | Invitrogen 14-5788-80 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

MICA/B Monoclonal Antibody (6D4), eBioscience

catalog :

14-5788-80

quantity :

25 µg

price :

US 96

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6D4

reactivity :

human

application :

immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry

citations: 8

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human immunohistochemistry; human	Ikeshita S, Miyatake Y, Otsuka N, Kasahara M. MICA/B expression in macrophage foam cells infiltrating atherosclerotic plaques. Exp Mol Pathol. 2014;97:171-5 pubmed publisher
	Shimizu T, Tomogane M, Miyashita M, Ukimura O, Ashihara E. Low dose gemcitabine increases the cytotoxicity of human Vγ9Vδ2 T cells in bladder cancer cells in vitro and in an orthotopic xenograft model. Oncoimmunology. 2018;7:e1424671 pubmed publisher
	Yin X, Lu X, Xiuwen Z, Min Z, Xiao R, Mao Z, et al. Role of NKG2D in cytokine-induced killer cells against lung cancer. Oncol Lett. 2017;13:3139-3143 pubmed publisher
	Xia M, Guerra N, Sukhova G, Yang K, Miller C, Shi G, et al. Immune activation resulting from NKG2D/ligand interaction promotes atherosclerosis. Circulation. 2011;124:2933-43 pubmed publisher
	Takao S, Ishikawa T, Yamashita K, Uchiyama T. The rapid induction of HLA-E is essential for the survival of antigen-activated naive CD4 T cells from attack by NK cells. J Immunol. 2010;185:6031-40 pubmed publisher
	Paschen A, Sucker A, Hill B, Moll I, Zapatka M, Nguyen X, et al. Differential clinical significance of individual NKG2D ligands in melanoma: soluble ULBP2 as an indicator of poor prognosis superior to S100B. Clin Cancer Res. 2009;15:5208-15 pubmed publisher
	Uzunel M, Kasimu H, Joshi M, Ge X, Liu J, Xu B, et al. Evidence for no relevance of anti-major histocompatibility complex class I-related chain a antibodies in liver transplantation. Liver Transpl. 2008;14:1793-802 pubmed publisher
	Groh V, Steinle A, Bauer S, Spies T. Recognition of stress-induced MHC molecules by intestinal epithelial gammadelta T cells. Science. 1998;279:1737-40 pubmed

product information

Product Type :

Antibody

Product Name :

MICA/B Monoclonal Antibody (6D4), eBioscience

Catalog # :

14-5788-80

Quantity :

25 µg

Price :

US 96

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 0.5 µg/test, Functional Assay: Assay-Dependent, Immunohistochemistry: Assay-Dependent, Immunoprecipitation: Assay-Dependent

Species :

Human

Clone :

6D4

Isotype :

IgG2a, kappa

Storage :

4° C

Description :

MICA encodes the higly polymorphic MHC (HLA) class I chain-related gene A. The protein product is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.5 µg/test, Functional Assay: Assay-Dependent, Immunohistochemistry: Assay-Dependent, Immunoprecipitation: Assay-Dependent

Aliases :

HLA class I antigen; MHC class I chain-related protein A; MHC class I chain-related protein B; MHC class I mic-B antigen; MHC class I polypeptide-related sequence A; MHC class I polypeptide-related sequence B; MHC class I related sequence A; MHC class I-like molecule PERB11.2-IMX; MICA; MIC-A; MICB; MIC-B; PERB11.1; PERB11.2; sMICA; sMICB; soluble MICA; soluble MICB; stress inducible class I homolog; truncated MHC class I polypeptide-related sequence A