IKAROS Monoclonal Antibody (2A9-mIkaros), eBioscience | Invitrogen 14-5780-82 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

IKAROS Monoclonal Antibody (2A9-mIkaros), eBioscience

catalog :

14-5780-82

quantity :

100 ug

price :

US 404.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2A9-mIkaros

reactivity :

mouse

application :

western blot

citations: 6

Reference
Harman C, Bailis W, Zhao J, Hill L, Qu R, Jackson R, et al. An in vivo screen of noncoding loci reveals that Daedalus is a gatekeeper of an Ikaros-dependent checkpoint during haematopoiesis. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
Liu S, Sun Q. Sex differences, endogenous sex-hormone hormones, sex-hormone binding globulin, and exogenous disruptors in diabetes and related metabolic outcomes. J Diabetes. 2018;10:428-441 pubmed publisher
John L, Ward A. The Ikaros gene family: transcriptional regulators of hematopoiesis and immunity. Mol Immunol. 2011;48:1272-8 pubmed publisher
Jeannet R, Mastio J, Macias Garcia A, Oravecz A, Ashworth T, Geimer Le Lay A, et al. Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL. Blood. 2010;116:5443-54 pubmed publisher
Cobb B, Morales Alcelay S, Kleiger G, Brown K, Fisher A, Smale S. Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding. Genes Dev. 2000;14:2146-60 pubmed
Georgopoulos K, Moore D, Derfler B. Ikaros, an early lymphoid-specific transcription factor and a putative mediator for T cell commitment. Science. 1992;258:808-12 pubmed

product information

Product Type :

Antibody

Product Name :

IKAROS Monoclonal Antibody (2A9-mIkaros), eBioscience

Catalog # :

14-5780-82

Quantity :

100 ug

Price :

US 404.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Mouse

Applications :

Western Blot: 1-5 ug/mL

Species :

Mouse

Clone :

2A9-mIkaros

Isotype :

IgG1

Storage :

4 C

Description :

DNA-binding protein IKAROS functions in the specification and the maturation of the T lymphocyte. It also interacts with a critical control element in the terminal deoxynucleotidyl transferase promoter as well as with the promoters for other genes expressed during early stages of B-cell and T-cell development.

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1-5 ug/mL

Aliases :

5832432G11Rik; CLL-associated antigen KW-6; CVID13; DNA-binding protein Ikaros; hIk-1; hlk-1; Hs.54452; IK1; IKAROS; IKAROS family zinc finger 1; IKAROS family zinc finger 1 (Ikaros); ikaros family zinc finger protein 1; IKZF1; KAROS family zinc finger 1 (Ikaros); LYF1; LyF-1; Lymphoid transcription factor LyF-1; mKIAA4227; PPP1R92; PRO0758; protein phosphatase 1, regulatory subunit 92; RGD1562979; Zfpn1a1; zinc finger containing transcription factor; zinc finger protein, subfamily 1A, 1 (Ikaros); Znfn1a1