product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Galectin 3 Monoclonal Antibody (eBioM3/38 (M3/38)), eBioscience™
catalog :
14-5301-82
quantity :
100µg
price :
US 174
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
eBioM3/38 (M3/38)
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 22
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 2a
Quenum Zangbede F, Chauhan A, Sharma J, Mishra B. Galectin-3 in M2 Macrophages Plays a Protective Role in Resolution of Neuropathology in Brain Parasitic Infection by Regulating Neutrophil Turnover. J Neurosci. 2018;38:6737-6750 pubmed publisher
Noguchi K, Tomita H, Kanayama T, Niwa A, Hatano Y, Hoshi M, et al. Time-course analysis of cardiac and serum galectin-3 in viral myocarditis after an encephalomyocarditis virus inoculation. PLoS ONE. 2019;14:e0210971 pubmed publisher
Tomita K, Kohli R, MacLaurin B, Hirsova P, Guo Q, Sanchez L, et al. Mixed-lineage kinase 3 pharmacological inhibition attenuates murine nonalcoholic steatohepatitis. JCI Insight. 2017;2: pubmed publisher
Soofi A, Wolf K, Emont M, Qi N, Martinez Santibañez G, Grimley E, et al. The kielin/chordin-like protein (KCP) attenuates high-fat diet-induced obesity and metabolic syndrome in mice. J Biol Chem. 2017;292:9051-9062 pubmed publisher
Sun X, Li C, Liu Y, Du L, Zeng M, Zheng X, et al. T-Cell Mineralocorticoid Receptor Controls Blood Pressure by Regulating Interferon-Gamma. Circ Res. 2017;120:1584-1597 pubmed publisher
Companioni Nápoles O, Tsao A, Sanz Anquela J, Sala N, Bonet C, Pardo M, et al. SCHLAFEN 5 expression correlates with intestinal metaplasia that progresses to gastric cancer. J Gastroenterol. 2017;52:39-49 pubmed publisher
Ilmer M, Mazurek N, Byrd J, Ramirez K, Hafley M, Alt E, et al. Cell surface galectin-3 defines a subset of chemoresistant gastrointestinal tumor-initiating cancer cells with heightened stem cell characteristics. Cell Death Dis. 2016;7:e2337 pubmed publisher
Hisamatsu K, Niwa M, Kobayashi K, Miyazaki T, Hirata A, Hatano Y, et al. Galectin-3 expression in hippocampal CA2 following transient forebrain ischemia and its inhibition by hypothermia or antiapoptotic agents. Neuroreport. 2016;27:311-7 pubmed publisher
Xie C, Ginet V, Sun Y, Koike M, Zhou K, Li T, et al. Neuroprotection by selective neuronal deletion of Atg7 in neonatal brain injury. Autophagy. 2016;12:410-23 pubmed publisher
Smolders S, Smolders S, Swinnen N, Gärtner A, Rigo J, Legendre P, et al. Maternal immune activation evoked by polyinosinic:polycytidylic acid does not evoke microglial cell activation in the embryo. Front Cell Neurosci. 2015;9:301 pubmed publisher
Lawler C, Milho R, May J, Stevenson P. Rhadinovirus host entry by co-operative infection. PLoS Pathog. 2015;11:e1004761 pubmed publisher
Endo J, Sano M, Isobe Y, Fukuda K, Kang J, Arai H, et al. 18-HEPE, an n-3 fatty acid metabolite released by macrophages, prevents pressure overload-induced maladaptive cardiac remodeling. J Exp Med. 2014;211:1673-87 pubmed publisher
Martinez Santibañez G, Cho K, Lumeng C. Imaging white adipose tissue with confocal microscopy. Methods Enzymol. 2014;537:17-30 pubmed publisher
Mishra B, Li Q, Steichen A, Binstock B, Metzger D, Teale J, et al. Galectin-3 functions as an alarmin: pathogenic role for sepsis development in murine respiratory tularemia. PLoS ONE. 2013;8:e59616 pubmed publisher
Ryu J, Davidson B, Xie A, Qi Y, Zha D, Belcik J, et al. Molecular imaging of the paracrine proangiogenic effects of progenitor cell therapy in limb ischemia. Circulation. 2013;127:710-9 pubmed publisher
Mueller S, Vanguri V, Ha S, West E, Keir M, Glickman J, et al. PD-L1 has distinct functions in hematopoietic and nonhematopoietic cells in regulating T cell responses during chronic infection in mice. J Clin Invest. 2010;120:2508-15 pubmed publisher
Ilchmann A, Burgdorf S, Scheurer S, Waibler Z, Nagai R, Wellner A, et al. Glycation of a food allergen by the Maillard reaction enhances its T-cell immunogenicity: role of macrophage scavenger receptor class A type I and II. J Allergy Clin Immunol. 2010;125:175-83.e1-11 pubmed publisher
Pilling D, Fan T, Huang D, Kaul B, Gomer R. Identification of markers that distinguish monocyte-derived fibrocytes from monocytes, macrophages, and fibroblasts. PLoS ONE. 2009;4:e7475 pubmed publisher
Southworth R, Kaneda M, Chen J, Zhang L, Zhang H, Yang X, et al. Renal vascular inflammation induced by Western diet in ApoE-null mice quantified by (19)F NMR of VCAM-1 targeted nanobeacons. Nanomedicine. 2009;5:359-67 pubmed publisher
Oliveira F, Frazao P, Chammas R, Hsu D, Liu F, Borojevic R, et al. Kinetics of mobilization and differentiation of lymphohematopoietic cells during experimental murine schistosomiasis in galectin-3 -/- mice. J Leukoc Biol. 2007;82:300-10 pubmed
Joo H, Goedegebuure P, Sadanaga N, Nagoshi M, von Bernstorff W, Eberlein T. Expression and function of galectin-3, a beta-galactoside-binding protein in activated T lymphocytes. J Leukoc Biol. 2001;69:555-64 pubmed
Ho M, Springer T. Mac-2, a novel 32,000 Mr mouse macrophage subpopulation-specific antigen defined by monoclonal antibodies. J Immunol. 1982;128:1221-8 pubmed
product information
Product Type :
Antibody
Product Name :
Galectin 3 Monoclonal Antibody (eBioM3/38 (M3/38)), eBioscience™
Catalog # :
14-5301-82
Quantity :
100µg
Price :
US 174
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Human, Mouse
Applications :
ELISA: Assay-Dependent, Flow Cytometry: 0.25 µg/test, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: Assay-Dependent
Species :
Human, Mouse
Clone :
eBioM3/38 (M3/38)
Isotype :
IgG2a, kappa
Storage :
4° C
Description :
Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
Format :
Liquid
Applications w/Dilutions :
ELISA: Assay-Dependent, Flow Cytometry: 0.25 µg/test, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: Assay-Dependent
Aliases :
35 kDa lectin; advanced glycation end-product receptor 3; AGE-R3; beta-galactosides-binding lectin; Carbohydrate-binding protein 35; CBP 35; CBP30; CBP-30; CBP35; epsilon BP; gal3; Gal-3; Galactose-specific lectin 3; Galactoside-binding protein; GALBP; Galectin3; Galectin-3; GALIG; GBP; IgE binding protein; IgE-binding protein; L-29; L31; L-31; L-34; L-34 galactoside-binding lectin; Laminin-binding protein; lectin galactoside-binding soluble 3 protein; Lectin L-29; lectin, galactose binding, soluble 3; lectin, galactoside binding soluble 3; lectin, galactoside-binding, soluble, 3; lectin, galactoside-binding, soluble, 3 (galectin 3); LGALS2; LGALS3; MAC2; Mac-2; Mac-2 antigen
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA