Ephrin B1 Monoclonal Antibody (25H11), eBioscience | Invitrogen 14-5300-80 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Ephrin B1 Monoclonal Antibody (25H11), eBioscience

catalog :

14-5300-80

quantity :

25 ug

price :

US 124.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

25H11

reactivity :

mouse

application :

immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - frozen section

citations: 4

Reference
Arthur A, Zannettino A, Panagopoulos R, Koblar S, Sims N, Stylianou C, et al. EphB/ephrin-B interactions mediate human MSC attachment, migration and osteochondral differentiation. Bone. 2011;48:533-42 pubmed publisher
Ogawa K, Wada H, Okada N, Harada I, Nakajima T, Pasquale E, et al. EphB2 and ephrin-B1 expressed in the adult kidney regulate the cytoarchitecture of medullary tubule cells through Rho family GTPases. J Cell Sci. 2006;119:559-70 pubmed
Davy A, Aubin J, Soriano P. Ephrin-B1 forward and reverse signaling are required during mouse development. Genes Dev. 2004;18:572-83 pubmed
Stuckmann I, Weigmann A, Shevchenko A, Mann M, Huttner W. Ephrin B1 is expressed on neuroepithelial cells in correlation with neocortical neurogenesis. J Neurosci. 2001;21:2726-37 pubmed

product information

Product Type :

Antibody

Product Name :

Ephrin B1 Monoclonal Antibody (25H11), eBioscience

Catalog # :

14-5300-80

Quantity :

25 ug

Price :

US 124.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Immunocytochemistry: 10 ug/mL, Immunohistochemistry (Frozen): 10 ug/mL, Immunoprecipitation: Assay-Dependent

Species :

Mouse

Clone :

25H11

Isotype :

IgG2a, kappa

Storage :

4 C

Description :

Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 10 ug/mL, Immunohistochemistry (Frozen): 10 ug/mL, Immunoprecipitation: Assay-Dependent

Aliases :

CEK5 ligand; CEK5 receptor ligand; CEK5-L; CEL5-L; CFND; CFNS; EFB1; EFL3; EFL-3; EFL6; EFNB1; EFNB3; ELK ligand; ELK-L; EPH-related receptor tyrosine kinase ligand 2; ephrin B1; Ephrin B3; EphrinB1; ephrin-B1; Ephrin-B1 C-terminal fragment; Ephrin-B1 CTF; Ephrin-B1 ICD; Ephrin-B1 intracellular domain; Ephrin-B1 precursor; Epl2; EPLG2; EPLG8; kinase ephrin-B1; Lerk2; LERK-2; LERK8; Stimulated by retinoic acid gene 1 protein; Stra1; STRA1 protein; transmembrane ligand