CD8b Monoclonal Antibody (SIDI8BEE), eBioscience | Invitrogen 14-5273-37 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD8b Monoclonal Antibody (SIDI8BEE), eBioscience

catalog :

14-5273-37

quantity :

2 mg

price :

US 1492.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

SIDI8BEE

reactivity :

human

application :

western blot, immunoprecipitation, flow cytometry

citations: 6

Reference
Statzu M, Jin W, Fray E, Wong A, Kumar M, Ferrer E, et al. CD8+ lymphocytes do not impact SIV reservoir establishment under ART. Nat Microbiol. 2023;8:299-308 pubmed publisher
Strittmatter Keller U, Walter C, Rauld C, Egli N, Regairaz C, Rabe S, et al. Fingerprints of CD8+ T cells on human pre-plasma and memory B cells. PLoS ONE. 2018;13:e0208187 pubmed publisher
Van Caeneghem Y, De Munter S, Tieppo P, Goetgeluk G, Weening K, Verstichel G, et al. Antigen receptor-redirected T cells derived from hematopoietic precursor cells lack expression of the endogenous TCR/CD3 receptor and exhibit specific antitumor capacities. Oncoimmunology. 2017;6:e1283460 pubmed publisher
Komdeur F, Wouters M, Workel H, Tijans A, Terwindt A, Brunekreeft K, et al. CD103+ intraepithelial T cells in high-grade serous ovarian cancer are phenotypically diverse TCRÎ±Î²+ CD8Î±Î²+ T cells that can be targeted for cancer immunotherapy. Oncotarget. 2016;7:75130-75144 pubmed publisher
Beura L, Hamilton S, Bi K, Schenkel J, Odumade O, Casey K, et al. Normalizing the environment recapitulates adult human immune traits in laboratory mice. Nature. 2016;532:512-6 pubmed publisher
Van de Walle I, Dolens A, Durinck K, De Mulder K, Van Loocke W, Damle S, et al. GATA3 induces human T-cell commitment by restraining Notch activity and repressing NK-cell fate. Nat Commun. 2016;7:11171 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD8b Monoclonal Antibody (SIDI8BEE), eBioscience

Catalog # :

14-5273-37

Quantity :

2 mg

Price :

US 1492.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human, Non-human primate

Applications :

Flow Cytometry: 0.125 ug/test, Immunoprecipitation: Assay-Dependent, Western Blot: Assay-Dependent

Species :

Human, Non-human primate

Clone :

SIDI8BEE

Isotype :

IgG1, kappa

Storage :

4 C

Description :

The CD8B antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.125 ug/test, Immunoprecipitation: Assay-Dependent, Western Blot: Assay-Dependent

Aliases :

CD8; CD8 antigen 37 kDa chain; CD8 antigen beta polypeptide; CD8 antigen beta polypeptide precursor; CD8 antigen beta-chain; CD8 antigen, beta chain; CD8 antigen, beta chain 1; CD8 antigen, beta polypeptide 1 (p37); CD8 antigen, beta-chain; CD8 beta; CD8 beta chain; CD8a; CD8alpha; CD8B; CD8b antigen; CD8b molecule; CD8b molecule pseudogene; CD8B1; CD8beta; CD8BP; LEU2; Leu-2; LY3; Ly-3; Ly-C; Lymphocyte antigen 3; Lyt3; Lyt-3; MAL; OX-8 membrane antigen; p32; P37; T lymphocyte surface glycoprotein beta chain; T-cell membrane glycoprotein Ly-3; T-cell surface glycoprotein; T-cell surface glycoprotein CD8 beta chain; T-cell surface glycoprotein Lyt-3