phospho-Tyrosine Monoclonal Antibody (pY20), eBioscience | Invitrogen 14-5001-37 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

phospho-Tyrosine Monoclonal Antibody (pY20), eBioscience

catalog :

14-5001-37

quantity :

2 mg

price :

US 1482.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

PY20

application :

western blot, immunoprecipitation, flow cytometry

citations: 4

Reference
Oseguera López I, Pérez Cerezales S, Ortiz Sánchez P, Mondragon Payne O, Sanchez Sanchez R, Jiménez Morales I, et al. Perfluorooctane Sulfonate (PFOS) and Perfluorohexane Sulfonate (PFHxS) Alters Protein Phosphorylation, Increase ROS Levels and DNA Fragmentation during In Vitro Capacitation of Boar Spermatozoa. Animals (Basel). 2020;10: pubmed publisher
Ruiz Díaz S, Oseguera López I, De La Cuesta Díaz D, García López B, Serres C, Sanchez Calabuig M, et al. The Presence of D-Penicillamine during the In Vitro Capacitation of Stallion Spermatozoa Prolongs Hyperactive-Like Motility and Allows for Sperm Selection by Thermotaxis. Animals (Basel). 2020;10: pubmed publisher
Majkowski M, Laszkiewicz A, Sniezewski L, Grzmil P, Pawlicka B, Tomczyk I, et al. Lack of NWC protein (c11orf74 homolog) in murine spermatogenesis results in reduced sperm competitiveness and impaired ability to fertilize egg cells in vitro. PLoS ONE. 2018;13:e0208649 pubmed publisher
Yamakawa N, Tsuchida K, Sugino H. The rasGAP-binding protein, Dok-1, mediates activin signaling via serine/threonine kinase receptors. EMBO J. 2002;21:1684-94 pubmed

product information

Product Type :

Antibody

Product Name :

phospho-Tyrosine Monoclonal Antibody (pY20), eBioscience

Catalog # :

14-5001-37

Quantity :

2 mg

Price :

US 1482.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Chemical

Applications :

Flow Cytometry: Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: Assay-Dependent

Species :

Chemical

Clone :

pY20

Isotype :

IgG2b, kappa

Storage :

4 C

Description :

The role of tyrosine phosphorylation in transduction of the mitogenic signal from transmembrane receptors and in transformation by oncogene tyrosine kinases has been the subject of intense investigation for several years. While the phosphorylation of specific tyrosine residues has been shown to be a primary mechanism of signal transduction during normal mitogenesis, cell cycle progression and oncogenic transformation, its role in other areas such as differentiation and gap junction communication, is a matter of active and ongoing research. Antibodies that specifically recognize phosphorylated tyrosine residues have proved to be invaluable to the study of tyrosine -phosphorylated proteins and the biochemical pathways in which they function. The fluorescein (FITC) conjugate of clone PY20 anti-phosphotyrosine is especially useful for the detection of these P-Tyr proteins in immunohistochemical and immunocytochemical protocols in situations wherein the use of a secondary antibody would complicate detection of the protein(s) of interest.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: Assay-Dependent

Aliases :

Phosphotyrosine; pTyr; pY