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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
EOMES Monoclonal Antibody (21Mags8), eBioscience™
catalog :
14-4876-82
quantity :
100µg
price :
US 249
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
21Mags8
reactivity :
human, mouse
application :
western blot, immunocytochemistry, flow cytometry
more info or order :
citations: 9
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; fig 4a
Weigelin B, Bolaños E, Teijeira A, Martinez Forero I, Labiano S, Azpilikueta A, et al. Focusing and sustaining the antitumor CTL effector killer response by agonist anti-CD137 mAb. Proc Natl Acad Sci U S A. 2015;112:7551-6 pubmed publisher
  • immunocytochemistry; mouse; 1:200; loading ...; fig 2e
Weidgang C, Russell R, Tata P, Kühl S, Illing A, Muller M, et al. TBX3 Directs Cell-Fate Decision toward Mesendoderm. Stem Cell Reports. 2013;1:248-65 pubmed publisher
Krausgruber T, Schiering C, Adelmann K, Harrison O, Chomka A, Pearson C, et al. T-bet is a key modulator of IL-23-driven pathogenic CD4(+) T cell responses in the intestine. Nat Commun. 2016;7:11627 pubmed publisher
Cho J, Kim H, Kim K, Yang D, Surh C, Sprent J. Unique features of naive CD8+ T cell activation by IL-2. J Immunol. 2013;191:5559-73 pubmed publisher
Edwards L, Haluszczak C, Kedl R. Phenotype and function of protective, CD4-independent CD8 T cell memory. Immunol Res. 2013;55:135-45 pubmed publisher
Wang C, Lee J, Kim C. Optimal population of FoxP3+ T cells in tumors requires an antigen priming-dependent trafficking receptor switch. PLoS ONE. 2012;7:e30793 pubmed publisher
Costello I, Pimeisl I, Dräger S, Bikoff E, Robertson E, Arnold S. The T-box transcription factor Eomesodermin acts upstream of Mesp1 to specify cardiac mesoderm during mouse gastrulation. Nat Cell Biol. 2011;13:1084-91 pubmed publisher
Bhadra R, Guan H, Khan I. Absence of both IL-7 and IL-15 severely impairs the development of CD8 T cell response against Toxoplasma gondii. PLoS ONE. 2010;5:e10842 pubmed publisher
Intlekofer A, Banerjee A, Takemoto N, Gordon S, Dejong C, Shin H, et al. Anomalous type 17 response to viral infection by CD8+ T cells lacking T-bet and eomesodermin. Science. 2008;321:408-11 pubmed publisher
product information
Product Type :
Antibody
Product Name :
EOMES Monoclonal Antibody (21Mags8), eBioscience™
Catalog # :
14-4876-82
Quantity :
100µg
Price :
US 249
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Human, Mouse
Applications :
Flow Cytometry: Assay-Dependent, Western Blot: 2 µg/mL
Species :
Human, Mouse
Clone :
21Mags8
Isotype :
IgG2a, kappa
Storage :
4° C
Description :
TBR2 is a member of a conserved protein family that shares a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similiar protein disrupted in mice is shown to be essential during trophoblast development and gastrulation. TBR2 plays a role in brain development and is required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: Assay-Dependent, Western Blot: 2 µg/mL
Aliases :
BOS_20809; C77258; Eomes; eomesodermin; Eomesodermin homolog; eomesodermin homolog (Xenopus laevis); T-box brain protein 2; Tbr2; TBR-2; T-brain-2
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA