EOMES Monoclonal Antibody (21Mags8), eBioscience™ | Invitrogen 14-4876-80 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

EOMES Monoclonal Antibody (21Mags8), eBioscience™

catalog :

14-4876-80

quantity :

25µg

price :

US 117

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

21Mags8

reactivity :

human, mouse

application :

western blot, flow cytometry

more info or order :

Invitrogen product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:500; fig 5	Krausgruber T, Schiering C, Adelmann K, Harrison O, Chomka A, Pearson C, et al. T-bet is a key modulator of IL-23-driven pathogenic CD4(+) T cell responses in the intestine. Nat Commun. 2016;7:11627 pubmed publisher
flow cytometry; mouse; fig 4a	Weigelin B, BolaÃ±os E, Teijeira A, Martinez Forero I, Labiano S, Azpilikueta A, et al. Focusing and sustaining the antitumor CTL effector killer response by agonist anti-CD137 mAb. Proc Natl Acad Sci U S A. 2015;112:7551-6 pubmed publisher
	Weidgang C, Russell R, Tata P, Kühl S, Illing A, Muller M, et al. TBX3 Directs Cell-Fate Decision toward Mesendoderm. Stem Cell Reports. 2013;1:248-65 pubmed publisher
	Cho J, Kim H, Kim K, Yang D, Surh C, Sprent J. Unique features of naive CD8+ T cell activation by IL-2. J Immunol. 2013;191:5559-73 pubmed publisher
	Edwards L, Haluszczak C, Kedl R. Phenotype and function of protective, CD4-independent CD8 T cell memory. Immunol Res. 2013;55:135-45 pubmed publisher
	Wang C, Lee J, Kim C. Optimal population of FoxP3+ T cells in tumors requires an antigen priming-dependent trafficking receptor switch. PLoS ONE. 2012;7:e30793 pubmed publisher
	Costello I, Pimeisl I, DrÃ¤ger S, Bikoff E, Robertson E, Arnold S. The T-box transcription factor Eomesodermin acts upstream of Mesp1 to specify cardiac mesoderm during mouse gastrulation. Nat Cell Biol. 2011;13:1084-91 pubmed publisher
	Bhadra R, Guan H, Khan I. Absence of both IL-7 and IL-15 severely impairs the development of CD8 T cell response against Toxoplasma gondii. PLoS ONE. 2010;5:e10842 pubmed publisher
	Intlekofer A, Banerjee A, Takemoto N, Gordon S, Dejong C, Shin H, et al. Anomalous type 17 response to viral infection by CD8+ T cells lacking T-bet and eomesodermin. Science. 2008;321:408-11 pubmed publisher

product information

Product Type :

Antibody

Product Name :

EOMES Monoclonal Antibody (21Mags8), eBioscience™

Catalog # :

14-4876-80

Quantity :

25µg

Price :

US 117

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Human, Mouse

Applications :

Flow Cytometry: Assay-Dependent, Western Blot: 2 µg/mL

Species :

Human, Mouse

Clone :

21Mags8

Isotype :

IgG2a, kappa

Storage :

4° C

Description :

TBR2 is a member of a conserved protein family that shares a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similiar protein disrupted in mice is shown to be essential during trophoblast development and gastrulation. TBR2 plays a role in brain development and is required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-Dependent, Western Blot: 2 µg/mL

Aliases :

BOS_20809; C77258; Eomes; eomesodermin; Eomesodermin homolog; eomesodermin homolog (Xenopus laevis); T-box brain protein 2; Tbr2; TBR-2; T-brain-2

more info or order :

Invitrogen product webpage