product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
EOMES Monoclonal Antibody (Dan11mag), eBioscience™
catalog :
14-4875-82
quantity :
100 µg
price :
US 309.00
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
Dan11mag
reactivity :
black flying fox, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 127
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:400; loading ...; fig s3j
  • immunocytochemistry; mouse; 1:400; fig s1f
Mukhtar T, Breda J, Grison A, Karimaddini Z, Grobecker P, Iber D, et al. Tead transcription factors differentially regulate cortical development. Sci Rep. 2020;10:4625 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 3a, 3b
Parisi G, Saco J, Salazar F, Tsoi J, Krystofinski P, Puig Saus C, et al. Persistence of adoptively transferred T cells with a kinetically engineered IL-2 receptor agonist. Nat Commun. 2020;11:660 pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; fig 2i
Panagiotakos G, Haveles C, Arjun A, Petrova R, Rana A, Portmann T, et al. Aberrant calcium channel splicing drives defects in cortical differentiation in Timothy syndrome. elife. 2019;8: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2k, s3n
Leone R, Zhao L, Englert J, Sun I, Oh M, Sun I, et al. Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion. Science. 2019;366:1013-1021 pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; fig 1s2a1b
S nchez Guardado L, Lois C. Lineage does not regulate the sensory synaptic input of projection neurons in the mouse olfactory bulb. elife. 2019;8: pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 1u
Nakagawa N, Plestant C, Yabuno Nakagawa K, Li J, Lee J, Huang C, et al. Memo1-Mediated Tiling of Radial Glial Cells Facilitates Cerebral Cortical Development. Neuron. 2019;: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3f
Khan O, Giles J, McDonald S, Manne S, Ngiow S, Patel K, et al. TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion. Nature. 2019;: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1b
Li J, He Y, Hao J, Ni L, Dong C. High Levels of Eomes Promote Exhaustion of Anti-tumor CD8+ T Cells. Front Immunol. 2018;9:2981 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5e
Tilstra J, Avery L, Menk A, Gordon R, Smita S, Kane L, et al. Kidney-infiltrating T cells in murine lupus nephritis are metabolically and functionally exhausted. J Clin Invest. 2018;128:4884-4897 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 7a
Singh M, Ni M, Sullivan J, Hamerman J, Campbell D. B cell adaptor for PI3-kinase (BCAP) modulates CD8+ effector and memory T cell differentiation. J Exp Med. 2018;215:2429-2443 pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig 3c
Zhu L, Xie X, Zhang L, Wang H, Jie Z, Zhou X, et al. TBK-binding protein 1 regulates IL-15-induced autophagy and NKT cell survival. Nat Commun. 2018;9:2812 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 4e
Wang B, Joo J, Mount R, Teubner B, Krenzer A, Ward A, et al. The COPII cargo adapter SEC24C is essential for neuronal homeostasis. J Clin Invest. 2018;128:3319-3332 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4e
Khan A, Carpenter B, Santos e Sousa P, Pospori C, Khorshed R, Griffin J, et al. Redirection to the bone marrow improves T cell persistence and antitumor functions. J Clin Invest. 2018;128:2010-2024 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig s6a
Silva C, Peyre E, Adhikari M, Tielens S, Tanco S, Van Damme P, et al. Cell-Intrinsic Control of Interneuron Migration Drives Cortical Morphogenesis. Cell. 2018;172:1063-1078.e19 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1g
Omilusik K, Nadjsombati M, Shaw L, Yu B, Milner J, Goldrath A. Sustained Id2 regulation of E proteins is required for terminal differentiation of effector CD8+ T cells. J Exp Med. 2018;215:773-783 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 6a
Kotov D, Kotov J, Goldberg M, Jenkins M. Many Th Cell Subsets Have Fas Ligand-Dependent Cytotoxic Potential. J Immunol. 2018;200:2004-2012 pubmed publisher
  • flow cytometry; mouse; fig s6c
Danahy D, Anthony S, Jensen I, Hartwig S, Shan Q, Xue H, et al. Polymicrobial sepsis impairs bystander recruitment of effector cells to infected skin despite optimal sensing and alarming function of skin resident memory CD8 T cells. PLoS Pathog. 2017;13:e1006569 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s12a
Billerbeck E, Wolfisberg R, Fahnøe U, Xiao J, Quirk C, Luna J, et al. Mouse models of acute and chronic hepacivirus infection. Science. 2017;357:204-208 pubmed publisher
  • flow cytometry; mouse; fig s3b
Knudson K, Pritzl C, Saxena V, Altman A, Daniels M, Teixeiro E. NFκB-Pim-1-Eomesodermin axis is critical for maintaining CD8 T-cell memory quality. Proc Natl Acad Sci U S A. 2017;114:E1659-E1667 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s7
Chamoto K, Chowdhury P, Kumar A, Sonomura K, Matsuda F, Fagarasan S, et al. Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity. Proc Natl Acad Sci U S A. 2017;114:E761-E770 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 2c
Ohs I, Van Den Broek M, Nussbaum K, MUNZ C, Arnold S, Quezada S, et al. Interleukin-12 bypasses common gamma-chain signalling in emergency natural killer cell lymphopoiesis. Nat Commun. 2016;7:13708 pubmed publisher
  • flow cytometry; black flying fox; 0.7 ug/ml; loading ...; fig 1b
Martínez Gómez J, Periasamy P, Dutertre C, Irving A, Ng J, Crameri G, et al. Phenotypic and functional characterization of the major lymphocyte populations in the fruit-eating bat Pteropus alecto. Sci Rep. 2016;6:37796 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4i
Hu Y, Kim J, He K, Wan Q, Kim J, Flach M, et al. Scramblase TMEM16F terminates T cell receptor signaling to restrict T cell exhaustion. J Exp Med. 2016;213:2759-2772 pubmed
  • immunohistochemistry; mouse; 1:200; loading ...; fig s9
Broix L, Jagline H, Ivanova E, Schmucker S, Drouot N, Clayton Smith J, et al. Mutations in the HECT domain of NEDD4L lead to AKT-mTOR pathway deregulation and cause periventricular nodular heterotopia. Nat Genet. 2016;48:1349-1358 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2f
Hoegl S, Ehrentraut H, Brodsky K, Victorino F, Golden Mason L, Eltzschig H, et al. NK cells regulate CXCR2+ neutrophil recruitment during acute lung injury. J Leukoc Biol. 2017;101:471-480 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2d
Lewis G, Wehrens E, Labarta Bajo L, Streeck H, Zuniga E. TGF-? receptor maintains CD4 T helper cell identity during chronic viral infections. J Clin Invest. 2016;126:3799-3813 pubmed publisher
  • flow cytometry; mouse; loading ...
Ladle B, Li K, Phillips M, Pucsek A, Haile A, Powell J, et al. De novo DNA methylation by DNA methyltransferase 3a controls early effector CD8+ T-cell fate decisions following activation. Proc Natl Acad Sci U S A. 2016;113:10631-6 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5a
Hwang S, Cobb D, Bhadra R, Youngblood B, Khan I. Blimp-1-mediated CD4 T cell exhaustion causes CD8 T cell dysfunction during chronic toxoplasmosis. J Exp Med. 2016;213:1799-818 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:250; loading ...; fig s2b
Wang L, Hou S, Han Y. Hedgehog signaling promotes basal progenitor expansion and the growth and folding of the neocortex. Nat Neurosci. 2016;19:888-96 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5a
Xu A, Bhanumathy K, Wu J, Ye Z, Freywald A, Leary S, et al. IL-15 signaling promotes adoptive effector T-cell survival and memory formation in irradiation-induced lymphopenia. Cell Biosci. 2016;6:30 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2c
Kurtulus S, Sakuishi K, Ngiow S, Joller N, Tan D, Teng M, et al. TIGIT predominantly regulates the immune response via regulatory T cells. J Clin Invest. 2015;125:4053-62 pubmed publisher
  • flow cytometry; mouse
Pearce V, Bouabe H, MacQueen A, Carbonaro V, Okkenhaug K. PI3Kδ Regulates the Magnitude of CD8+ T Cell Responses after Challenge with Listeria monocytogenes. J Immunol. 2015;195:3206-17 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2f
Ngiow S, Young A, Jacquelot N, Yamazaki T, Enot D, Zitvogel L, et al. A Threshold Level of Intratumor CD8+ T-cell PD1 Expression Dictates Therapeutic Response to Anti-PD1. Cancer Res. 2015;75:3800-11 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s2
Kim M, Taparowsky E, Kim C. Retinoic Acid Differentially Regulates the Migration of Innate Lymphoid Cell Subsets to the Gut. Immunity. 2015;43:107-19 pubmed publisher
  • flow cytometry; mouse; fig 1
Wensveen F, Jelenčić V, Valentić S, Šestan M, Wensveen T, Theurich S, et al. NK cells link obesity-induced adipose stress to inflammation and insulin resistance. Nat Immunol. 2015;16:376-85 pubmed publisher
  • flow cytometry; mouse
Dobenecker M, Kim J, Marcello J, Fang T, Prinjha R, Bosselut R, et al. Coupling of T cell receptor specificity to natural killer T cell development by bivalent histone H3 methylation. J Exp Med. 2015;212:297-306 pubmed publisher
  • flow cytometry; mouse
Spada R, Rojas J, Pérez Yagüe S, Mulens V, Cannata Ortiz P, Bragado R, et al. NKG2D ligand overexpression in lupus nephritis correlates with increased NK cell activity and differentiation in kidneys but not in the periphery. J Leukoc Biol. 2015;97:583-98 pubmed publisher
  • flow cytometry; mouse
Stoycheva D, Deiser K, Stärck L, Nishanth G, Schlüter D, Uckert W, et al. IFN-γ regulates CD8+ memory T cell differentiation and survival in response to weak, but not strong, TCR signals. J Immunol. 2015;194:553-9 pubmed publisher
  • flow cytometry; mouse
Hosking M, Flynn C, Whitton J. Antigen-specific naive CD8+ T cells produce a single pulse of IFN-γ in vivo within hours of infection, but without antiviral effect. J Immunol. 2014;193:1873-85 pubmed publisher
  • flow cytometry; mouse
Smith N, Wissink E, Wang J, Pinello J, Davenport M, Grimson A, et al. Rapid proliferation and differentiation impairs the development of memory CD8+ T cells in early life. J Immunol. 2014;193:177-84 pubmed publisher
  • flow cytometry; mouse
Lee J, Walsh M, Hoehn K, James D, Wherry E, Choi Y. Regulator of fatty acid metabolism, acetyl coenzyme a carboxylase 1, controls T cell immunity. J Immunol. 2014;192:3190-9 pubmed publisher
  • flow cytometry; mouse
Zhang N, Bevan M. TGF-? signaling to T cells inhibits autoimmunity during lymphopenia-driven proliferation. Nat Immunol. 2012;13:667-73 pubmed publisher
  • flow cytometry; mouse; fig 8
Marshall H, Prince A, Berg L, Welsh R. IFN-alpha beta and self-MHC divert CD8 T cells into a distinct differentiation pathway characterized by rapid acquisition of effector functions. J Immunol. 2010;185:1419-28 pubmed publisher
Kischel A, Audouard C, Fawal M, Davy A. Ephrin-B2 paces neuronal production in the developing neocortex. BMC Dev Biol. 2020;20:12 pubmed publisher
Nelson B, Hodge R, Daza R, Tripathi P, Arnold S, Millen K, et al. Intermediate progenitors support migration of neural stem cells into dentate gyrus outer neurogenic niches. elife. 2020;9: pubmed publisher
Kim K, Park S, Park S, Kim G, Park S, Cho J, et al. Single-cell transcriptome analysis reveals TOX as a promoting factor for T cell exhaustion and a predictor for anti-PD-1 responses in human cancer. Genome Med. 2020;12:22 pubmed publisher
Vacchio M, Ciucci T, Gao Y, Watanabe M, Balmaceno Criss M, McGinty M, et al. A Thpok-Directed Transcriptional Circuitry Promotes Bcl6 and Maf Expression to Orchestrate T Follicular Helper Differentiation. Immunity. 2019;51:465-478.e6 pubmed publisher
Ponzetta A, Carriero R, Carnevale S, Barbagallo M, Molgora M, Perucchini C, et al. Neutrophils Driving Unconventional T Cells Mediate Resistance against Murine Sarcomas and Selected Human Tumors. Cell. 2019;178:346-360.e24 pubmed publisher
Mielke L, Liao Y, Clemens E, Firth M, Duckworth B, Huang Q, et al. TCF-1 limits the formation of Tc17 cells via repression of the MAF-RORγt axis. J Exp Med. 2019;: pubmed publisher
Roy A, Murphy R, Deng M, MacDonald J, Bammler T, Aldinger K, et al. PI3K-Yap activity drives cortical gyrification and hydrocephalus in mice. elife. 2019;8: pubmed publisher
Zhou L, Chu C, Teng F, Bessman N, Goc J, Santosa E, et al. Innate lymphoid cells support regulatory T cells in the intestine through interleukin-2. Nature. 2019;568:405-409 pubmed publisher
Lavado A, Park J, Pare J, Finkelstein D, Pan H, Xu B, et al. The Hippo Pathway Prevents YAP/TAZ-Driven Hypertranscription and Controls Neural Progenitor Number. Dev Cell. 2018;47:576-591.e8 pubmed publisher
Rolot M, Dougall A, Chetty A, Javaux J, Chen T, Xiao X, et al. Helminth-induced IL-4 expands bystander memory CD8+ T cells for early control of viral infection. Nat Commun. 2018;9:4516 pubmed publisher
Lee S, Park H, Cheon J, Wu L, Van Kaer L, Hong S. iNKT Cells Suppress Pathogenic NK1.1+CD8+ T Cells in DSS-Induced Colitis. Front Immunol. 2018;9:2168 pubmed publisher
Almeida F, Tognarelli S, Marcais A, Kueh A, Friede M, Liao Y, et al. A point mutation in the Ncr1 signal peptide impairs the development of innate lymphoid cell subsets. Oncoimmunology. 2018;7:e1475875 pubmed publisher
Chowdhury P, Chamoto K, Kumar A, Honjo T. PPAR-Induced Fatty Acid Oxidation in T Cells Increases the Number of Tumor-Reactive CD8+ T Cells and Facilitates Anti-PD-1 Therapy. Cancer Immunol Res. 2018;6:1375-1387 pubmed publisher
Maurice D, Costello P, Sargent M, Treisman R. ERK Signaling Controls Innate-like CD8+ T Cell Differentiation via the ELK4 (SAP-1) and ELK1 Transcription Factors. J Immunol. 2018;201:1681-1691 pubmed publisher
Vitali I, Fièvre S, Telley L, Oberst P, Bariselli S, Frangeul L, et al. Progenitor Hyperpolarization Regulates the Sequential Generation of Neuronal Subtypes in the Developing Neocortex. Cell. 2018;174:1264-1276.e15 pubmed publisher
Noguchi N, Nakamura R, Hatano S, Yamada H, Sun X, Ohara N, et al. Interleukin-21 Induces Short-Lived Effector CD8+ T Cells but Does Not Inhibit Their Exhaustion after Mycobacterium bovis BCG Infection in Mice. Infect Immun. 2018;86: pubmed publisher
Drobek A, Moudra A, Mueller D, Huranová M, Horková V, Pribikova M, et al. Strong homeostatic TCR signals induce formation of self-tolerant virtual memory CD8 T cells. EMBO J. 2018;37: pubmed publisher
Hailemichael Y, Woods A, Fu T, He Q, Nielsen M, Hasan F, et al. Cancer vaccine formulation dictates synergy with CTLA-4 and PD-L1 checkpoint blockade therapy. J Clin Invest. 2018;128:1338-1354 pubmed publisher
Cuenca M, Puñet Ortiz J, Ruart M, Terhorst C, Engel P. Ly9 (SLAMF3) receptor differentially regulates iNKT cell development and activation in mice. Eur J Immunol. 2018;48:99-105 pubmed publisher
Hope J, Stairiker C, Spantidea P, Gracias D, Carey A, Fike A, et al. The Transcription Factor T-Bet Is Regulated by MicroRNA-155 in Murine Anti-Viral CD8+ T Cells via SHIP-1. Front Immunol. 2017;8:1696 pubmed publisher
Quatrini L, Wieduwild E, Guia S, Bernat C, Glaichenhaus N, Vivier E, et al. Host resistance to endotoxic shock requires the neuroendocrine regulation of group 1 innate lymphoid cells. J Exp Med. 2017;214:3531-3541 pubmed publisher
Wasiuk A, Testa J, Weidlick J, Sisson C, Vitale L, Widger J, et al. CD27-Mediated Regulatory T Cell Depletion and Effector T Cell Costimulation Both Contribute to Antitumor Efficacy. J Immunol. 2017;199:4110-4123 pubmed publisher
Delpoux A, Lai C, Hedrick S, Doedens A. FOXO1 opposition of CD8+ T cell effector programming confers early memory properties and phenotypic diversity. Proc Natl Acad Sci U S A. 2017;114:E8865-E8874 pubmed publisher
Wang H, Li J, Han Q, Yang F, Xiao Y, Xiao M, et al. IL-12 Influence mTOR to Modulate CD8+ T Cells Differentiation through T-bet and Eomesodermin in Response to Invasive Pulmonary Aspergillosis. Int J Med Sci. 2017;14:977-983 pubmed publisher
Chen Z, Stelekati E, Kurachi M, Yu S, Cai Z, Manne S, et al. miR-150 Regulates Memory CD8 T Cell Differentiation via c-Myb. Cell Rep. 2017;20:2584-2597 pubmed publisher
Zhang Y, Kurupati R, Liu L, Zhou X, Zhang G, Hudaihed A, et al. Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy. Cancer Cell. 2017;32:377-391.e9 pubmed publisher
Huber M, Suprunenko T, Ashhurst T, Marbach F, Raifer H, Wolff S, et al. IRF9 Prevents CD8+ T Cell Exhaustion in an Extrinsic Manner during Acute Lymphocytic Choriomeningitis Virus Infection. J Virol. 2017;91: pubmed publisher
Hosomi S, Grootjans J, Tschurtschenthaler M, Krupka N, Matute J, Flak M, et al. Intestinal epithelial cell endoplasmic reticulum stress promotes MULT1 up-regulation and NKG2D-mediated inflammation. J Exp Med. 2017;214:2985-2997 pubmed publisher
Nussbaum K, Burkhard S, Ohs I, Mair F, Klose C, Arnold S, et al. Tissue microenvironment dictates the fate and tumor-suppressive function of type 3 ILCs. J Exp Med. 2017;214:2331-2347 pubmed publisher
Gullicksrud J, Li F, Xing S, Zeng Z, Peng W, Badovinac V, et al. Differential Requirements for Tcf1 Long Isoforms in CD8+ and CD4+ T Cell Responses to Acute Viral Infection. J Immunol. 2017;199:911-919 pubmed publisher
Ghoneim H, Fan Y, Moustaki A, Abdelsamed H, Dash P, Dogra P, et al. De Novo Epigenetic Programs Inhibit PD-1 Blockade-Mediated T Cell Rejuvenation. Cell. 2017;170:142-157.e19 pubmed publisher
Probst S, Daza R, Bader N, Hummel J, Weiß M, Tanriver Y, et al. A dual-fluorescence reporter in the Eomes locus for live imaging and medium-term lineage tracing. Genesis. 2017;55: pubmed publisher
Neal L, Qiu Y, Chung J, Xing E, Cho W, Malachowski A, et al. T Cell-Restricted Notch Signaling Contributes to Pulmonary Th1 and Th2 Immunity during Cryptococcus neoformans Infection. J Immunol. 2017;199:643-655 pubmed publisher
Shan Q, Zeng Z, Xing S, Li F, Hartwig S, Gullicksrud J, et al. The transcription factor Runx3 guards cytotoxic CD8+ effector T cells against deviation towards follicular helper T cell lineage. Nat Immunol. 2017;18:931-939 pubmed publisher
Vasanthakumar A, Xu D, Lun A, Kueh A, van Gisbergen K, Iannarella N, et al. A non-canonical function of Ezh2 preserves immune homeostasis. EMBO Rep. 2017;18:619-631 pubmed publisher
Marshall N, Vong A, Devarajan P, Brauner M, Kuang Y, Nayar R, et al. NKG2C/E Marks the Unique Cytotoxic CD4 T Cell Subset, ThCTL, Generated by Influenza Infection. J Immunol. 2017;198:1142-1155 pubmed publisher
Haushalter C, Schuhbaur B, Dolle P, Rhinn M. Meningeal retinoic acid contributes to neocortical lamination and radial migration during mouse brain development. Biol Open. 2017;6:148-160 pubmed publisher
Utzschneider D, Alfei F, Roelli P, Barras D, Chennupati V, Darbre S, et al. High antigen levels induce an exhausted phenotype in a chronic infection without impairing T cell expansion and survival. J Exp Med. 2016;213:1819-34 pubmed publisher
Fame R, MacDonald J, Dunwoodie S, Takahashi E, Macklis J. Cited2 Regulates Neocortical Layer II/III Generation and Somatosensory Callosal Projection Neuron Development and Connectivity. J Neurosci. 2016;36:6403-19 pubmed publisher
Takeo Y, Kurabayashi N, Nguyen M, Sanada K. The G protein-coupled receptor GPR157 regulates neuronal differentiation of radial glial progenitors through the Gq-IP3 pathway. Sci Rep. 2016;6:25180 pubmed publisher
Rabacal W, Pabbisetty S, Hoek K, Cendron D, Guo Y, Maseda D, et al. Transcription factor KLF2 regulates homeostatic NK cell proliferation and survival. Proc Natl Acad Sci U S A. 2016;113:5370-5 pubmed publisher
Boulenouar S, Doisne J, Sferruzzi Perri A, Gaynor L, Kieckbusch J, Balmas E, et al. The Residual Innate Lymphoid Cells in NFIL3-Deficient Mice Support Suboptimal Maternal Adaptations to Pregnancy. Front Immunol. 2016;7:43 pubmed publisher
Hamblet C, Makowski S, Tritapoe J, Pomerantz J. NK Cell Maturation and Cytotoxicity Are Controlled by the Intramembrane Aspartyl Protease SPPL3. J Immunol. 2016;196:2614-26 pubmed publisher
Lin C, Erkek S, Tong Y, Yin L, Federation A, Zapatka M, et al. Active medulloblastoma enhancers reveal subgroup-specific cellular origins. Nature. 2016;530:57-62 pubmed publisher
Mackay L, Wynne Jones E, Freestone D, Pellicci D, Mielke L, Newman D, et al. T-box Transcription Factors Combine with the Cytokines TGF-β and IL-15 to Control Tissue-Resident Memory T Cell Fate. Immunity. 2015;43:1101-11 pubmed publisher
Luci C, Bekri S, Bihl F, Pini J, Bourdely P, Nouhen K, et al. NKp46+ Innate Lymphoid Cells Dampen Vaginal CD8 T Cell Responses following Local Immunization with a Cholera Toxin-Based Vaccine. PLoS ONE. 2015;10:e0143224 pubmed publisher
Gupta P, Godec J, Wolski D, Adland E, Yates K, Pauken K, et al. CD39 Expression Identifies Terminally Exhausted CD8+ T Cells. PLoS Pathog. 2015;11:e1005177 pubmed publisher
Pollizzi K, Patel C, Sun I, Oh M, Waickman A, Wen J, et al. mTORC1 and mTORC2 selectively regulate CD8⁺ T cell differentiation. J Clin Invest. 2015;125:2090-108 pubmed publisher
Pascutti M, Geerman S, Slot E, van Gisbergen K, Boon L, Arens R, et al. Enhanced CD8 T cell responses through GITR-mediated costimulation resolve chronic viral infection. PLoS Pathog. 2015;11:e1004675 pubmed publisher
Miyazaki M, Miyazaki K, Chen S, Chandra V, Wagatsuma K, Agata Y, et al. The E-Id protein axis modulates the activities of the PI3K-AKT-mTORC1-Hif1a and c-myc/p19Arf pathways to suppress innate variant TFH cell development, thymocyte expansion, and lymphomagenesis. Genes Dev. 2015;29:409-25 pubmed publisher
Yang M, Li D, Chang Z, Yang Z, Tian Z, Dong Z. PDK1 orchestrates early NK cell development through induction of E4BP4 expression and maintenance of IL-15 responsiveness. J Exp Med. 2015;212:253-65 pubmed publisher
Buchan S, Manzo T, Flutter B, Rogel A, Edwards N, Zhang L, et al. OX40- and CD27-mediated costimulation synergizes with anti-PD-L1 blockade by forcing exhausted CD8+ T cells to exit quiescence. J Immunol. 2015;194:125-133 pubmed publisher
Nair S, Fang M, Sigal L. The natural killer cell dysfunction of aged mice is due to the bone marrow stroma and is not restored by IL-15/IL-15Rα treatment. Aging Cell. 2015;14:180-90 pubmed publisher
Iwashita M, Kataoka N, Toida K, Kosodo Y. Systematic profiling of spatiotemporal tissue and cellular stiffness in the developing brain. Development. 2014;141:3793-8 pubmed publisher
Seillet C, Huntington N, Gangatirkar P, Axelsson E, Minnich M, Brady H, et al. Differential requirement for Nfil3 during NK cell development. J Immunol. 2014;192:2667-76 pubmed publisher
Mollo S, Ingram J, Kress R, Zajac A, Harrington L. Virus-specific CD4 and CD8 T cell responses in the absence of Th1-associated transcription factors. J Leukoc Biol. 2014;95:705-713 pubmed
Cho J, Kim H, Kim K, Yang D, Surh C, Sprent J. Unique features of naive CD8+ T cell activation by IL-2. J Immunol. 2013;191:5559-73 pubmed publisher
Hosking M, Flynn C, Botten J, Whitton J. CD8+ memory T cells appear exhausted within hours of acute virus infection. J Immunol. 2013;191:4211-22 pubmed publisher
Zumwalde N, Domae E, Mescher M, Shimizu Y. ICAM-1-dependent homotypic aggregates regulate CD8 T cell effector function and differentiation during T cell activation. J Immunol. 2013;191:3681-93 pubmed publisher
Knudson K, Goplen N, Cunningham C, Daniels M, Teixeiro E. Low-affinity T cells are programmed to maintain normal primary responses but are impaired in their recall to low-affinity ligands. Cell Rep. 2013;4:554-65 pubmed publisher
Yousefi M, Duplay P. CD28 controls the development of innate-like CD8+ T cells by promoting the functional maturation of NKT cells. Eur J Immunol. 2013;43:3017-27 pubmed publisher
Tejera M, Kim E, Sullivan J, Plisch E, Suresh M. FoxO1 controls effector-to-memory transition and maintenance of functional CD8 T cell memory. J Immunol. 2013;191:187-99 pubmed publisher
Sandy A, Chung J, Toubai T, Shan G, Tran I, Friedman A, et al. T cell-specific notch inhibition blocks graft-versus-host disease by inducing a hyporesponsive program in alloreactive CD4+ and CD8+ T cells. J Immunol. 2013;190:5818-28 pubmed publisher
Tse S, Cockburn I, Zhang H, Scott A, Zavala F. Unique transcriptional profile of liver-resident memory CD8+ T cells induced by immunization with malaria sporozoites. Genes Immun. 2013;14:302-9 pubmed publisher
Amoah S, Holbrook B, Yammani R, Alexander Miller M. High viral burden restricts short-lived effector cell number at late times postinfection through increased natural regulatory T cell expansion. J Immunol. 2013;190:5020-9 pubmed publisher
Masson F, Minnich M, Olshansky M, Bilic I, Mount A, Kallies A, et al. Id2-mediated inhibition of E2A represses memory CD8+ T cell differentiation. J Immunol. 2013;190:4585-94 pubmed publisher
Jia Y, Takeda K, Han J, Joetham A, Marcus R, Lucas J, et al. Stepwise epigenetic and phenotypic alterations poise CD8+ T cells to mediate airway hyperresponsiveness and inflammation. J Immunol. 2013;190:4056-65 pubmed publisher
Daudelin J, Mathieu M, Boulet S, Labrecque N. IL-6 production by dendritic cells is dispensable for CD8+ memory T-cell generation. Biomed Res Int. 2013;2013:126189 pubmed publisher
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product information
Product Type :
Antibody
Product Name :
EOMES Monoclonal Antibody (Dan11mag), eBioscience™
Catalog # :
14-4875-82
Quantity :
100 µg
Price :
US 309.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: Assay-Dependent, Immunohistochemistry (Paraffin): 5 µg/mL, Western Blot: 5 µg/mL
Species :
Mouse
Clone :
Dan11mag
Isotype :
IgG2a, kappa
Storage :
4° C
Description :
TBR2 is a member of a conserved protein family that shares a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similiar protein disrupted in mice is shown to be essential during trophoblast development and gastrulation. TBR2 plays a role in brain development and is required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: Assay-Dependent, Immunohistochemistry (Paraffin): 5 µg/mL, Western Blot: 5 µg/mL
Aliases :
C77258; EOMES; eomesodermin; eomesodermin homolog; eomesodermin homolog (Xenopus laevis); T-box brain protein 2; T-box transcription factor; TBR2; TBR-2; T-brain-2
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA